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Male Infertility

Systems Biology in Reproductive Medicine
According to the World Health Organization (WHO), infertility is the failure of a couple to achieve pregnancy after one year of consistent unprotected sex. Male factors contribute to about 50 percent of all infertility cases. Male infertility is a multifactorial disease that can stem from multiple etiologies which can be congenital or acquired.
Leslie SW, Soon-Sutton TL, Khan MAB.
europepmc   +4 more sources

Lycopene and male infertility

Asian Journal of Andrology, 2014
Excessive amounts of reactive oxygen species (ROS) cause a state of oxidative stress, which result in sperm membrane lipid peroxidation, DNA damage and apoptosis, leading to decreased sperm viability and motility. Elevated levels of ROS are a major cause
Damayanthi Durairajanayagam, Ashok Agarwal, Chloe Ong, Pallavi Prashast   +3 more
doaj   +3 more sources

Sperm Selection by Magnetic-Activated Cell Sorting before Microinjection of Autologous Oocytes Increases Cumulative Live Birth Rates with Limited Clinical Impact: A Retrospective Study in Unselected Males

Biology, 2021
The application of MACS non-apoptotic sperm selection in infertility clinics is controversial since the published literature does not agree on its effect on reproductive outcomes. Therefore, it is not part of the routine clinical practice.
María Gil Juliá, Irene Hervás, Ana Navarro-Gómez Lechón, Fernando Quintana, David Amorós, Alberto Pacheco, Cristina González-Ravina, Rocío Rivera-Egea, Nicolás Garrido   +8 more
doaj   +1 more source

Efficacy of Antioxidant Supplementation on Conventional and Advanced Sperm Function Tests in Patients with Idiopathic Male Infertility

Antioxidants, 2020
Antioxidants are used in the empirical treatment of infertile men. The aim of this study was to evaluate the effects of antioxidant therapy on conventional semen parameters and advanced sperm function tests in men seeking fertility treatment.
Mohamed Arafa, Ashok Agarwal, Ahmad Majzoub, Manesh Kumar Panner Selvam, Saradha Baskaran, Ralf Henkel, Haitham Elbardisi   +6 more
doaj   +1 more source

Effects of antioxidant co‐supplementation therapy on spermatogenesis dysfunction in relation to the basal oxidation–reduction potential levels in spermatozoa: A pilot study

Reproductive Medicine and Biology, 2022
Purpose In this pilot study, the authors compared the effects of antioxidant co‐supplementation therapy and methylcobalamin therapy in patients with impaired semen quality.
Kazumitsu Yamasaki, Masahiro Uchida, Noriko Watanabe, Tatsuji Ihana, Yukari Ishiguro, Shinnosuke Kuroda, Teppei Takeshima, Yasushi Yumura, Makiko Mieno, Kaoru Yoshida, Teruaki Iwamoto, Hiroyuki Nishiyama   +11 more
doaj   +1 more source

Effect of hormonal manipulation using clomiphene citrate prior to microdissection testicular sperm retrieval

Urology Annals, 2021
Introduction: Microdissection Testicular Sperm Extraction (micro-TESE) is a surgical method used for retrieving sperm from men with non-obstructive azoospermia.
Khalid Alrabeeah, Abdulmalik Addar, Ali Alothman, Saad Abu Melha, Abdullah Alkhayal   +4 more
doaj   +1 more source

Chromosomal Abnormalities in Iranian Infertile Males who are Candidates for Assisted Reproductive Techniques [PDF]

International Journal of Fertility and Sterility, 2007
Background: The present study offers our contribution on the topic by a retrospective analysis of the prevalence of chromosomal abnormalities in a population of Iranian infertile men attending assisted reproduction programs.Materials and Methods ...
iman salahshourifar, Mohammad Ali Sadighi Gilani, Najmeh sadat Masoudi, Hamid Gourabi   +3 more
doaj   +1 more source

The Microbiome, an Important Factor That Is Easily Overlooked in Male Infertility

Frontiers in Microbiology, 2022
Humankind has been interested in reproduction for millennia. Infertility, in which male factors contribute to approximately 50%, is estimated to concern over 72 million people worldwide.
Hefeng Wang, Anran Xu, Liping Gong, Zhaowen Chen, Bin Zhang, Xiuyun Li   +5 more
doaj   +1 more source

Impact of Microfluidic Sperm Sorting on Embryonic Euploidy in Infertile Patients with Sperm DNA Damage: A Retrospective Study [PDF]

International Journal of Fertility and Sterility
Background: Sperm DNA fragmentation is an important factor that affects male fertility. This study intends to evaluatethe impact of sperm DNA damage [single-strand breaks (SSB) and double-strand breaks (DSB)] on fertilisationand embryonic euploidy after ...
Sandra Lara-Cerrillo, Ana Raquel Jiménez Macedo, Olga Hortal, Candela Rosado Iglesias, Tania Lacruz Ruiz, Joan Carrera, Agustín García Peiró   +6 more
doaj   +1 more source

Antioxidants and Male Infertility

Antioxidants, 2022
Oxidative stress has been associated with decreased sperm quality and male infertility [...]
Ricardo Silva, David F. Carrageta, Marco G. Alves, Branca M. Silva, Pedro F. Oliveira   +4 more
doaj   +1 more source