Results 111 to 120 of about 1,522,848 (395)

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

open access: yesAdvanced Photonics Research, EarlyView.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka   +5 more
wiley   +1 more source

Role of Biologics in Asthma

open access: yesAmerican Journal of Respiratory and Critical Care Medicine, 2019
&NA; Patients with severe uncontrolled asthma have disproportionally high morbidity and healthcare utilization as compared with their peers with well‐controlled disease.
M. McGregor   +3 more
semanticscholar   +1 more source

A Systematic Approach to Analyze T Cell Migration: Application to Mouse Melanoma Tumors

open access: yesAdvanced Therapeutics, EarlyView.
The results show that a minimum of two migration speeds can be rigorously identified from the data with cells switching between a fast, persistent migratory state, and a slow, random migration state. These results will help in identifying genetic factors that influence rapid migration, among other applications, such as quality control for CAR‐T cell ...
Nikolaos Memmos   +4 more
wiley   +1 more source

Recent advances in understanding rhinovirus immunity [version 1; referees: 4 approved]

open access: yesF1000Research, 2018
Rhinoviruses are the most common cause of upper respiratory tract infections. However, they can induce exacerbations of chronic obstructive pulmonary disease and asthma, bronchiolitis in infants, and significant lower respiratory tract infections in ...
Spyridon Makris, Sebastian Johnston
doaj   +1 more source

GINA 2019: a fundamental change in asthma management

open access: yesEuropean Respiratory Journal, 2019
In April 2019, the Global Initiative for Asthma (GINA) (box 1) published new recommendations that might be considered the most fundamental change in asthma management in 30 years.
H. Reddel   +17 more
semanticscholar   +1 more source

The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma [PDF]

open access: yes, 2016
Chronic asthma is associated with persistent lung inflammation and long-term remodelling of the airways that have proved refractory to conventional treatments such as steroids, despite their efficacy in controlling acute airway contraction and bronchial ...
Al-Riyami, L.   +6 more
core   +1 more source

Asthma in the Elderly

open access: yesClinics in Geriatric Medicine, 2003
The older population has seen the greatest increase in the prevalence of current asthma in recent years. Asthma may begin at any age and when it occurs at an advanced as opposed to a young age, it is often nonatopic, severe, and unremitting. Unfortunately, geriatric-specific guidelines are not available for the diagnosis and treatment of asthma ...
openaire   +5 more sources

M2 Macrophages are Major Mediators of Germline Risk of Endometriosis and Explain Pleiotropy With Comorbid Traits

open access: yesAdvanced Science, EarlyView.
Genes associated with endometriosis risk are highly expressed in M2 macrophages, particularly ligands IL1A and IL1B. Endometrial‐type epithelium and stroma are likely recipients of these ligands. While IL1B treatment disturbs epithelial organization, blockage of the signaling results in a dose‐dependent decrease in spontanesous and evoked pain, reduces
Soledad Ochoa   +15 more
wiley   +1 more source

Environmental public health tracking of childhood asthma using California health interview survey, traffic, and outdoor air pollution data. [PDF]

open access: yes, 2008
BackgroundDespite extensive evidence that air pollution affects childhood asthma, state-level and national-level tracking of asthma outcomes in relation to air pollution is limited.ObjectivesOur goals were to evaluate the feasibility of linking the 2001 ...
Balmes, John   +5 more
core  

Early-Life Air Pollution Exposure, Neighborhood Poverty, and Childhood Asthma in the United States, 1990⁻2014. [PDF]

open access: yes, 2018
Ambient air pollution is a well-known risk factor of various asthma-related outcomes, however, past research has often focused on acute exacerbations rather than asthma development.
Crowder, Kyle   +5 more
core   +3 more sources

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