Results 111 to 120 of about 1,230,724 (345)

Brittle asthma

open access: yesMonaldi Archives for Chest Disease, 2016
Brittle asthma is a clinical phenotype of the disease at the severe end of the spectrum. Type 1 brittle asthma is characterised by a maintained wide PEF variability (> 40% diurnal variation for > 50% of the time over a period of at least 150 days) despite considerable medical therapy including a dose of inhaled steroids of at least 1500 μg of ...
TOUNGOUSSOVA O   +6 more
openaire   +5 more sources

CRISPLD2 Attenuates Intervertebral Disc Degeneration by Suppressing Oxidative Stress‐Induced Ferroptosis through the miR‐548I‐IL17A Axis

open access: yesAdvanced Science, EarlyView.
This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi   +11 more
wiley   +1 more source

Artificial Intelligence‐Driven Soft Bioelectronics for Self‐Powered Respiration Monitoring

open access: yesAdvanced Science, EarlyView.
Artificial intelligence‐driven soft bioelectronics for self powered respiration monitoring based on triboelectric nanogenerators (TENGs), piezoelectric nanogenerators (PENGs), and magnetoelastic generators (MEGs) enable continuous and multi‐scenario respiratory biomechanical data collection. Coupled with machine learning and big data driven diagnostics,
Xinkai Xu, Xiao Xiao, Rui Guo, Jun Chen
wiley   +1 more source

Osthole treatment ameliorates Th2-mediated allergic asthma and exerts immunomodulatory effects on dendritic cell maturation and function [PDF]

open access: bronze, 2017
Chen‐Yuan Chiang   +5 more
openalex   +1 more source

Cell‐Free DNA‐Based Theranostics for Inflammatory Disorders

open access: yesAdvanced Science, EarlyView.
Summary on the dual potential of cfDNA as biomarkers and therapeutic targets for inflammatory disorders. Figure was created with BioRender.com. ABSTRACT Inflammatory disorders are characterized by immune‐mediated inflammatory cascades that can affect multiple organs.
Jiatong Li   +7 more
wiley   +1 more source

Prevalence of Asthma Severities in Children and Adolescents in a Wilmington, DE Hospital [PDF]

open access: yes, 2018
Asthma affects over 24 million individuals in the US and the prevalence of the condition is increasing in the US and worldwide. The prevalence of severe persistent asthma, which incurs a significant health and economic burden, is still poorly understood ...
King, MD, MPH, Katherine   +2 more
core   +1 more source

Oxidative Stress in Asthma

open access: yesWorld Allergy Organization Journal, 2011
Asthma is a chronic inflammatory lung disease that results in airflow limitation, hyperreactivity, and airway remodeling. There is strong evidence that an imbalance between the reducing and oxidizing systems favoring a more oxidative state is present in ...
Umit M. Sahiner, MD   +4 more
doaj   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

open access: yesAdvanced Science, EarlyView.
Laser induced graphene offers a scalable route to flexible, porous gas sensor with tunable properties and self heating functionality. This summarizes the overview of the design and application landscape of LIG‐based wearable gas sensor in healthcare. ABSTRACT Direct laser irradiation of carbonaceous precursors such as polyimide and wood is a scalable ...
Md Abu Sayeed Biswas   +6 more
wiley   +1 more source

Pulmonary microRNA profiles identify involvement of Creb1 and Sec14l3 in bronchial epithelial changes in allergic asthma [PDF]

open access: gold, 2017
Sabine Bartel   +12 more
openalex   +1 more source

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