Results 51 to 60 of about 46,849 (195)

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

open access: yesAdvanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun   +5 more
wiley   +1 more source

Cardiac structure and function after revascularization versus medical therapy for renal artery stenosis: the ASTRAL heart echocardiographic sub-study

open access: yesBMC Nephrology, 2019
Background The ASTRAL trial showed no difference in clinical outcomes between medical therapy and revascularization for atherosclerotic renal vascular disease (ARVD).
Darren Green   +18 more
doaj   +1 more source

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

open access: yesAdvanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding   +10 more
wiley   +1 more source

Mechanisms of spindle positioning. [PDF]

open access: yes, 2013
Accurate positioning of spindles is essential for asymmetric mitotic and meiotic cell divisions that are crucial for animal development and oocyte maturation, respectively.
McNally, Francis J
core   +1 more source

Dynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegans. [PDF]

open access: yes, 2015
Oocyte meiotic spindles orient with one pole juxtaposed to the cortex to facilitate extrusion of chromosomes into polar bodies. In Caenorhabditis elegans, these acentriolar spindles initially orient parallel to the cortex and then rotate to the ...
Andaya, Armann   +9 more
core   +1 more source

Theory of Telepathy: an Alternative Interpretation of Psychotic Experiences and Some Tips for Recovery [PDF]

open access: yes, 2017
This article looks at mental illness, in particular psychotic mental illness, such as schizophrenia, and spirituality. It argues that the phenomenon of ‘voice hearing’, which is present in schizophrenia (but also other mental illnesses) can be understood
Beyer, Anna Cornelia
core   +1 more source

Weighted ASTRID: fast and accurate species trees from weighted internode distances

open access: yesAlgorithms for Molecular Biology, 2023
Background Species tree estimation is a basic step in many biological research projects, but is complicated by the fact that gene trees can differ from the species tree due to processes such as incomplete lineage sorting (ILS), gene duplication and loss (
Baqiao Liu, Tandy Warnow
doaj   +1 more source

An invariant of scale-free graphs [PDF]

open access: yes, 2015
In many applications (including biology and the study of computer networks) graphs are found to be scale-free. It has been argued that this property alone does not tell us much about the structure of the graph.
Vernitski, A
core  

DSK1, a novel kinesin-related protein from the diatom Cylindrotheca fusiformis that is involved in anaphase spindle elongation. [PDF]

open access: yes, 1996
We have identified an 80-kD protein that is involved in mitotic spindle elongation in the diatom Cylindrotheca fusiformis. DSK1 (Diatom Spindle Kinesin 1) was isolated using a peptide antibody raised against a conserved region in the motor domain of the ...
Brady, B   +3 more
core   +2 more sources

THE OEDIPUS MYTH AS MATHEMATICAL ALLEGORY

open access: yesRevista Brasileira de História da Matemática, 2020
We posit that, for many ancient thinkers, mathematical allegory was a fundamental theoretical construct in their understanding of the universe. The procedure is to establish a noteworthy mathematical structure which suggests certain physical or social ...
John A. Fossa, Glenn W. Erickson
doaj   +1 more source

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