Results 131 to 140 of about 57,588 (263)
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot +6 more
wiley +1 more source
IGFBP7+ subpopulation and IGFBP7 risk score in astrocytoma: insights from scRNA-Seq and bulk RNA-Seq
BackgroundGlioma is the predominant malignant brain tumor that lacks effective treatment options due to its shielding by the blood-brain barrier (BBB).
Liang Zhao +8 more
doaj +1 more source
The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo +5 more
wiley +1 more source
CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang +11 more
wiley +1 more source
Glioblastoma (GBM) is a highly aggressive brain tumor with a poor prognosis, driven by abnormal signaling pathways that promote growth and resistance to treatment. Conventional therapies are inadequate, highlighting the need for novel multitargeted approaches.
Mehrukh Zehravi +13 more
wiley +1 more source
Expression of TERRA in Different Grades of Astrocytoma
Background: Brain tumors include burden of mortality from cancers. High grades of brain tumors are more aggressive and have poor prognosis. Introduction telomeres are the ends of linear chromosomes that serve as a protective cap to avoid permanent ...
Sepideh Dashti +2 more
doaj
Study of Adaptive Radiotherapy for High‐Grade Glioma Based on Interfraction MRI
ABSTRACT Background Currently, there is no clear guidance on the appropriate population or timing for adaptive radiotherapy (ART) in high‐grade glioma (HGG) patients. This study aims to provide individualized ART for HGG patients. Methods Participants received standard “radiotherapy combined with temozolomide” and underwent MRI before radiotherapy (FX0)
Shuangshuang He +12 more
wiley +1 more source
ABSTRACT Novel adjuvant hemostatic agents are increasingly used in surgical procedures to achieve hemostasis. We present a case of embolisation of hemostatic agents during a neurosurgical operation, causing massive PE requiring venoarterial extracorporeal membrane oxygenation support, in a 7‐year‐old boy.
Talya Finke +3 more
wiley +1 more source
ABSTRACT Retinal astrocytichamartoma (RAH) is a rare benign glial neoplasm most commonly associated with tuberous sclerosis complex (TSC). Sporadic cases, occurring in the absence of systemic phakomatosis, are uncommon and may closely mimic retinoblastoma, particularly when presenting with a calcified intraocular mass, creating a diagnostic challenge ...
Mesfin Wubishet Gurmu +7 more
wiley +1 more source
Comparison of level of endothelial progenitor cells (epcs) in astrocytoma to adjacent normal brain tissue [PDF]
Introduction: Astrocytomas are the most common primary brain tumors which account for up to two third of all tumors of glial origin and especially the high grade astrocytoma are known to be highly vascularized.
Chee How, Ch’ng
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