Results 131 to 140 of about 87,399 (317)

A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. [PDF]

open access: yes, 2000
A randomized, multicentre, open-label, phase II study compared temozolomide (TMZ), an oral second-generation alkylating agent, and procarbazine (PCB) in 225 patients with glioblastoma multiforme at first relapse.
Albright, RE   +21 more
core  

MAP17 Enhances Chemoresistance and Tumorigenicity of Glioblastoma‐Initiating Cells via the Canonical NF‐кB Pathway

open access: yesCancer Science, EarlyView.
MAP 17 is identified as highly expressed in TMZ‐resistant glioblastoma‐initiating cells (GICs). MAP17 enhances GIC proliferation, TMZ resistance, and tumorigenicity through NF‐κB/RELA‐dependent BCL2 upregulation. ABSTRACT Glioblastoma (GBM) is the most common malignant brain tumor in adults.
Shenshen Dou, You Lee Son, Toru Kondo
wiley   +1 more source

Advances in Molecular Pathology, Diagnosis and Treatment of Spinal Cord Astrocytomas

open access: yesTechnology in Cancer Research & Treatment
Spinal cord astrocytoma (SCA) is a rare subtype of astrocytoma, posing challenges in diagnosis and treatment. Low-grade SCA can achieve long-term survival solely through surgery, while high-grade has a disappointing prognosis even with comprehensive ...
Zijun Zhao MD   +5 more
doaj   +1 more source

Three-dimensional cultured glioma cell lines [PDF]

open access: yes
Three-dimensional glioma spheroids were produced in vitro with size and histological differentiation previously unattained. The spheroids were grown in liquid media suspension in a Johnson Space Center (JSC) Rotating Wall Bioreactor without using support
Gonda, Steve R., Marley, Garry M.
core   +1 more source

A Nationwide Central Diagnosis for Pediatric CNS Tumors in Japan: The JCCG Brain Tumor and Pathology Committees

open access: yesCancer Science, EarlyView.
In this report, we present the results of a nationwide initiative launched by the Japan Children's Cancer Group to provide integrated diagnoses for pediatric central nervous system (CNS) tumors, incorporating central pathological review and molecular profiling.
Yoshiko Nakano   +39 more
wiley   +1 more source

Couple Dynamics Following Brain Cancer Diagnosis: A Scoping Review

open access: yesJournal of Family Theory &Review, EarlyView.
ABSTRACT In this scoping review, we examine the psychosocial impacts and relationship experiences of brain cancer on patients and their romantic partners. We synthesize seven empirical studies published between 2000 and 2024 across the United States (n = 2) and Europe (n = 5).
Nick Frye‐Cox   +4 more
wiley   +1 more source

The Efficacy of Pharmacotherapy Intervention on Anthropometric Outcomes in Survivors of Childhood Brain Tumors: An Updated Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, EarlyView.
ABSTRACT Introduction Many survivors of childhood brain tumors face long‐term adverse health outcomes like obesity. Uncertainties surround the effect of interventions to manage obesity‐related outcomes in survivors of childhood brain tumors. The goal of this updated systematic review and meta‐analysis was to provide the best estimate of the treatment ...
David Hart   +11 more
wiley   +1 more source

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