Results 161 to 170 of about 57,588 (263)

The High Cost of Misdiagnosis: The Challenges of Differentiating Grade-4 Astrocytoma from Glioblastoma in Resource-Constrained Countries. [PDF]

Pak J Med Sci
Saeed H, Qadri HM.
europepmc   +1 more source

Couple Dynamics Following Brain Cancer Diagnosis: A Scoping Review

Journal of Family Theory &Review, Volume 18, Issue 3, Page 737-749, September 2026.
ABSTRACT In this scoping review, we examine the psychosocial impacts and relationship experiences of brain cancer on patients and their romantic partners. We synthesize seven empirical studies published between 2000 and 2024 across the United States (n = 2) and Europe (n = 5).
Nick Frye‐Cox, Zoee Johnson, Olivia Shores, Maria Boccia, Jennifer H. Murillo   +4 more
wiley   +1 more source

Pitfalls in 2HG Detection With TE‐Optimized MRS at 3T

Journal of Neuroimaging, Volume 36, Issue 5, September/October 2026.
ABSTRACT Background and Purpose In vivo MRS of 2‐hydroxyglutarate (2HG) may provide diagnostic and monitoring biomarkers in isocitrate dehydrogenase (IDH)‐mutated glioma. A previous meta‐analysis has shown good diagnostic accuracy of TE‐optimized PRESS for IDH‐mutated glioma, but most studies feature IDH‐wildtype glioma as a comparison.
Seyma Alcicek, Dunja Simicic, Lindsay Blair, Max Saint‐Germain, Helge J. Zöllner, Christopher W. Davies‐Jenkins, Matthias Holdhoff, John Laterra, Chetan Bettegowda, Karisa C. Schreck, Doris D. Lin, Peter B. Barker, David O. Kamson, Georg Oeltzschner   +13 more
wiley   +1 more source

IDH-Mutant Diffuse Glioma: From Metabolic Origins to Targeted Therapy. [PDF]

J Clin Med
Urbanic-Purkart T.
europepmc   +1 more source

Efficacy and Safety of Bariatric Surgery in Acquired Hypothalamic Obesity: A Systematic Review and Individual Patient Data Meta‐Analysis

Obesity Reviews, Volume 27, Issue 9, September 2026.
ABSTRACT Objective This work aimed to investigate the efficacy and safety of Roux‐en‐Y gastric bypass (RYGB) and sleeve gastrectomy (SG) in adults with acquired hypothalamic obesity (HO). Design Systematic review and meta‐analysis. Methods Publications reporting relevant outcomes in patients with HO before and after RYGB or SG were identified through a
Johannes Fessler, Pauline Faucher, Christine Poitou, Carsten Dirksen   +3 more
wiley   +1 more source

The critical issue of grade 2 vs grade 3 in IDH-mutant gliomas. [PDF]

Neuro Oncol
Ng HK.
europepmc   +1 more source

Re‐evaluation of salt of aspartame‐acesulfame (E 962) as food additive

EFSA Journal, Volume 24, Issue 9, September 2026.
Abstract The present opinion deals with the re‐evaluation of salt of aspartame‐acesulfame (E 962) as a food additive. The Panel considered that upon ingestion, E 962 dissociates into aspartame and acesulfame ions which correspond to those of the authorised sweeteners aspartame (E 951) and acesulfame K (E 950). The Panel therefore assessed the safety of
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Rex FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Ellen Bruzell, Cristina Fortes, Kevin James Chipman, Riccardo Crebelli, Peter Fürst, Jean‐Charles Leblanc, Evangelia Ntzani, Andrea Terron, Matthew Wright, Stefania Barmaz, Costanza Bonnici, Consuelo Civitella, Elena Mazzoli, Josef Daniel Rasinger, Ana Rincon, Camilla Smeraldi, Alexandra Tard, Federica Lodi   +34 more
wiley   +1 more source

A MAGIBU-based model for pediatric and juvenile CNS tumors: an in-house epigenetic decision-support framework compared with online DNA methylation classifiers. [PDF]

Free Neuropathol
Mattei G, Giunti L, Scagnet M, Agushi R, Mussa F, Caporalini C, Sardi I, Civale VY, Magi A, Genitori L, Buccoliero AM.   +10 more
europepmc   +1 more source

From Fragments to Function: Novel Hydrazone Derivatives as Monoamine Oxidase Inhibitors

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Twelve N‐acylhydrazone derivatives (5a–f, 6a–f) were synthesized and characterized. Compounds displayed potent submicromolar inhibition against both MAO‐A and MAO‐B. Compound 6e exhibited the strongest activity (IC50 = 0.073 μM for MAO‐A; 0.064 μM for MAO‐B). Kinetic and docking analyses confirmed reversible, competitive inhibition via FAD interaction.
Hasan Erdinç Sellitepe, Ahmet Buğra Aksel, Ezgi Pehlivanlar Yavrucu, Hilal Zıvalı, Begüm Nurpelin Sağlık Özkan, İnci Selin Doğan   +5 more
wiley   +1 more source

Social vulnerability and survival among patients with high-grade glioma treated at a tertiary cancer center. [PDF]

J Neurooncol
Hsi AH, Wathoo C, Campbell E, Nassif M, Buchold GM, Nguyen LH, McNeill LH, Hawk E, Puduvalli VK, Kamiya-Matsuoka C.   +9 more
europepmc   +1 more source