Results 171 to 180 of about 87,399 (317)

Case Report on Anaplastic Astrocytoma: Diagnostic and Therapeutic Challenges [PDF]

Gummalla Prema Florence
openalex   +1 more source

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, Volume 73, Issue 6, June 2026.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Advancements in Glioblastoma Multiforme Treatment: A Comprehensive Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 16, Issue 5, May 2026.
This study is a systematic review and meta‐analysis comparing bevacizumab‐, temozolomide‐, and lomustine‐based treatments for recurrent glioblastoma. The findings suggest that monotherapy, particularly bevacizumab, may provide better clinical outcomes with fewer adverse events than combination regimens. ABSTRACT Background Glioblastoma multiforme (GBM)
Kayode Agboola, Fatemeh Khafaji, Bipin Chaurasia, Kashif Qureshi, Kivanc Yangi, Vishal Chavda, Naci Balak   +6 more
wiley   +1 more source

Transformer‐Based Deep Learning Model for Predicting Recurrence in High‐Grade Glioma

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Introduction The first year after treatment for high‐grade glioma (HGG) is recognized as the peak interval for recurrence. Accurate prediction of recurrence during this period is critical for timely management and early intervention. This study aimed to develop a fusion model that integrates MRI‐derived features with clinical variables ...
Xin Wang, Mingjun Ding, Dan Zong, Pudong Qian, Xia He   +4 more
wiley   +1 more source

Integrated Molecular Profiling Improves Subtype Classification and Reveals Inherited Susceptibility in Medulloblastoma: Insights From a Real‐World Cohort

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Medulloblastoma (MB) is a heterogeneous pediatric brain tumor characterized by distinct molecular subtypes. Although genomics and transcriptomics have improved subtype classification and informed targeted therapies, the clinical utility of integrated molecular profiling in real‐world settings remains incompletely defined. Methods We
Jiwei Song, Tiantian Han, Siqi Chen, Dongsheng Chen, Ziying Liu   +4 more
wiley   +1 more source

MULTIFOCAL GLIOBLASTOMA MULTIFORME PRECEDED BY A GEMISTOCYTIC ASTROCYTOMA AND DYSREGULATED IMMUNE RESPONSE [PDF]

, 2014
Ilian G. Koev, E. Slavov, Hristo Zhelyazkov, D. G. Staikov, Krasimira Halacheva, Victoria Sarafian   +5 more
openalex   +1 more source

Ventriculoperitoneal Shunt Malfunction: The Importance of Topogram Image Observation

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Disconnection of a ventriculoperitoneal shunt is a serious complication. The “sunset eye” sign is an important indicator of hydrocephalus. Observation of a CT topogram is an important diagnostic measure and should not be overlooked, and good care of the ventriculoperitoneal shunt should also be taken.
Yantao Du, Xiongwei Ding, Wenquan Wang, Yanhui Du   +3 more
wiley   +1 more source

Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications

MedComm, Volume 7, Issue 5, May 2026.
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang, Xiaoqing Wang, Kai Luo, Tikam Chand Dakal, He Bai, Caiming Xu, Guixin Zhang   +6 more
wiley   +1 more source

A Case of IDH-Mutant Astrocytoma Harboring an IDH2 R172_H173delinsSN Variant. [PDF]

Neuropathology
Auen T, Chen J, Shonka N, Cathcart S.
europepmc   +1 more source

Spinal astrocytoma

, 2016
Sigmund Stuppner
openalex   +1 more source