Results 61 to 70 of about 834,230 (306)
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Alternative Asymmetric Stochastic Volatility Models [PDF]
The stochastic volatility model usually incorporates asymmetric effects by introducing the negative correlation between the innovations in returns and volatility.
Michael McAleer, Manabu Asai
core +6 more sources
What is (not) asymmetric conflict? From conceptual stretching to conceptual structuring
, 2019 In the second half of the 1990s, the label “asymmetric” conflict rose to prominence among scholars and strategists, as a term for capturing the rising challenge that violent non-state actors posed to the liberal world order.
Berglund, Christofer, +3 more
core +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
, 2017 Asymmetric war can be defined as a way of fighting by a belligerent who rejects the rules of engagement and principles that underlie the strategic culture of its opponent, and uses methods which are unexpected, alien, and not acceptable by the adversary. Thus, it takes advantage of the psychological effects of culture shock and works by defeating one's
openaire +2 more sources
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Analysis and Geometry in Metric Spaces, 2013 Abstract In this paper we discuss asymmetric length structures and asymmetric metric spaces. A length structure induces a (semi)distance function; by using the total variation formula, a (semi)distance function induces a length. In the first part we identify a topology in the set of paths that best describes when the above operations are
openaire +4 more sources
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Nature CommunicationsAsymmetric catalysis for enantioselective intramolecular hydroamination of alkenes is a critical method in the construction of enantioenriched nitrogen-containing rings, often prevalent in biologically active compounds and natural products.
Bin Cui +6 more
doaj +1 more source