Results 71 to 80 of about 1,020,177 (314)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Tuning the properties of coumarin-based small molecule donors via strong acceptor substitution for advanced donor/PCBM organic solar cells

Scientific African
In this study, we designed and evaluated high-efficiency coumarin-based small-molecule donors for organic solar cells (OSCs) using density functional theory (DFT) calculations to address the challenge of improving charge transfer and photovoltaic ...
Walid Taouali, Mourad Chemek, Kamel Alimi   +2 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Modern Approaches for Asymmetric Construction of Carbon−Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

Chemical Reviews, 2018
New methods for preparation of tailormade fluorine-containing compounds are in extremely high demand in nearly every sctor of chemical industry. The asymmetric construction of quaternary C−F stereogenic centers is the most synthetically challenging and ...
Yi Zhu, Jianlin Han, Jiandong Wang, N. Shibata, M. Sodeoka, V. Soloshonok, V. Soloshonok, Jaime A. S. Coelho, F. Toste   +8 more
semanticscholar   +1 more source

Asymmetric War

, 2017
Asymmetric war can be defined as a way of fighting by a belligerent who rejects the rules of engagement and principles that underlie the strategic culture of its opponent, and uses methods which are unexpected, alien, and not acceptable by the adversary. Thus, it takes advantage of the psychological effects of culture shock and works by defeating one's
openaire   +2 more sources

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Carbohydrate-Based Hydrogels: Weaving Nature’s Versatility into Biomedical Innovation

International Journal of Nanomedicine
Camilla Maria Cova, Alessio Zuliani, Noureddine Khiar Asymmetric Synthesis and Nanosystems Group (Art&Fun), Institute for Chemical Research (IIQ), CSIC-University of Seville, Seville, 41092, SpainCorrespondence: Noureddine Khiar, Asymmetric Synthesis
Cova CM, Zuliani A, Khiar N
doaj  

Evaluation of the Heat Transfer Performance of a Device Utilizing an Asymmetric Pulsating Heat Pipe Structure Based on Global and Local Analysis

Energies
PHPs (pulsating heat pipes) are widely used as an efficient heat transfer element in equipment thermal management and waste heat recovery due to their flexibility. The purpose of this study was to design a heat transfer device that utilizes an asymmetric
Dong Liu, Jianhong Liu, Kai Yang, Fumin Shang, Chaofan Zheng, Xin Cao   +5 more
doaj   +1 more source