Results 51 to 60 of about 1,649,451 (289)

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

Left-ventricular geometry in young persons with connective tissue dysplasia

open access: yesЛечащий Врач, 2021
Assessment of left-ventricular geometry in slightly pronounced variants of connective tissue dysplasia (CTD) was done, in order to define a fine dividing line between unconditioned norm and first signs of pathology.
M. I. Shupina   +4 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer

open access: yesNature Communications, 2019
Tumour necrosis factor (TNF) is a cytokine belonging to a family of trimeric proteins; it has been shown to be a key mediator in autoimmune diseases such as rheumatoid arthritis and Crohn’s disease.
J. O’Connell   +17 more
semanticscholar   +1 more source

Adaptive Fuzzy Control for Nontriangular Stochastic High-Order Nonlinear Systems Subject to Asymmetric Output Constraints

open access: yesIEEE Transactions on Cybernetics, 2020
In this article, an adaptive fuzzy control design strategy is presented for $p$ -norm nontriangular stochastic high-order nonlinear systems with asymmetric output constraints and unknown nonlinearities.
Liandi Fang   +3 more
semanticscholar   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Hybrid Cryptography with a One–Time Stamp to Secure Contact Tracing for COVID–19 Infection

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2022
The COVID-19 pandemic changed the lives of millions of citizens worldwide in the manner they live and work to the so-called new norm in social standards.
El-Douh Ahmed Abdel-Rahim   +3 more
doaj   +1 more source

Discrete Semantics-Guided Asymmetric Hashing for Large-Scale Multimedia Retrieval

open access: yesApplied Sciences, 2021
Cross-modal hashing technology is a key technology for real-time retrieval of large-scale multimedia data in real-world applications. Although the existing cross-modal hashing methods have achieved impressive accomplishment, there are still some ...
Jun Long   +3 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

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