Results 61 to 70 of about 9,927,693 (264)

Characterisation of the Interaction among Oil-In-Water Nanocapsules and Mucin

Biomimetics, 2020
Mucins are glycoproteins present in all mucosal surfaces and in secretions such as saliva. Mucins are involved in the mucoadhesion of nanodevices carrying bioactive molecules to their target sites in vivo.
Mar Collado-González, Gurmeet Kaur, Yadira González-Espinosa, Rebecca Brooks, Francisco M. Goycoolea   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Impact of asymmetrical flow field-flow fractionation on protein aggregates stability [PDF]

Journal of Chromatography A, 2016
The impact of asymmetrical flow field-flow fractionation (AF4) on protein aggregate species is investigated with the aid of multiangle light scattering (MALS) and dynamic light scattering (DLS). The experimental parameters probed in this study include aggregate stability in different carrier liquids, shear stress (related to sample injection), sample ...
Carmen R M, Bria, S Kim Ratanathanawongs, Williams   +1 more
openaire   +2 more sources

Increasing the resolution of field flow fractionation with increasing crossflow gradients [PDF]

, 2023
The resolution of flow field flow fractionation (flow FFF) depends primarily on the crossflow rate and its change over time. In this work we demonstrate a method for modulation of the crossflow rate during separation increases the peak-to-peak resolution
George, Bou-Assaf, Nicholas, Larson
core   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

The Contribution of Endmembers to Mixtures of Leaf Leachates and Riverine DOM can be Determined by Measuring Their Size and Fluorescence Properties

Frontiers in Environmental Chemistry, 2022
The molecular mass distribution (MMD) and fluorescence properties of dissolved organic matter (DOM) are important characteristics for tracing and predicting its pathways, processes, and fate in aquatic systems. For the first time, asymmetrical flow field-
C. W. Cuss, C. Guéguen
doaj   +1 more source

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

A comparative analysis of extracellular vesicles (EVs) from human and feline plasma

Scientific Reports, 2022
Extracellular vesicles (EVs) are nanoparticles found in all biological fluids, capable of transporting biological material around the body. Extensive research into the physiological role of EVs has led to the development of the Minimal Information for ...
Jane Howard, Kieran Wynne, Evelin Moldenhauer, Paul Clarke, Ciaran Maguire, Stephanie Bollard, Xiaofei Yin, Lorraine Brennan, Louise Mooney, Stephen Fitzsimons, Melinda Halasz, Ester Rani Aluri, Dermot F. Brougham, Walter Kolch, Róisín M. Dwyer, Shirley Potter, Pamela Kelly, Amanda McCann   +17 more
doaj   +1 more source

Turbulent structures, integral length scale and turbulent kinetic energy (TKE) dissipation rate in compound channel flow [PDF]

, 2017
In the present study, high data rate measurements were obtained for the streamwise and vertical velocity components using 2D Laser Doppler Velocimeter. The turbulent field in a straight compound-channel flow was characterized for three different uniform ...
Roja-Solórzano, Luís R., Bento Leal, João, Ricardo, Azevedo, Azevedo, Ricardo   +3 more
core   +1 more source

Is an Apple an Orange? A Large Language Model Benchmark for Candidate Term Extraction and Subclass Decisions Against Upper Ontologies in Engineering and Materials Science

Advanced Engineering Materials, EarlyView.
Building machine‐readable vocabularies for materials science is slow, expert‐driven work. This study benchmarks 13 large language models on two of its first steps: finding candidate terms in engineering articles and deciding where they belong in a class hierarchy.
Thomas Bjarsch, Maximilian Holland, Klaus Drechsler, Johannes Schilp   +3 more
wiley   +1 more source