Results 121 to 130 of about 64,339 (258)

Repeating Nuclear Transients From Repeating Partial Tidal Disruption Events

Astronomische Nachrichten, EarlyView.
ABSTRACT Extragalactic nuclear transients that exhibit repeating outbursts can be modeled as the repeated dynamical interaction between bound stars and supermassive black holes (SMBHs). A subset of these transients, with recurrence timescales of months‐to‐years, have been explained as accretion flares from the repeated tidal stripping of a star by an ...
Ananya Bandopadhyay, Eric R. Coughlin, Julia Fancher, C. J. Nixon, Dheeraj R. Pasham   +4 more
wiley   +1 more source

Asymptotic analysis of optimal vaccination policies

, 2022
Penn MJ, Donnelly CA.
europepmc   +1 more source

Discrete Element Method Modeling of an Extrusion Process with Recirculation for Dry Manufacturing of Lithium‐Ion Battery Electrodes

Batteries &Supercaps, EarlyView.
On a digitized laboratory extruder, discrete element method modelling is studied, considering two classes of particles representing aggregates of 1) active material and 2) binder and carbon material is studied. Various extrusion scenarios leading to the formation of filaments devoted to the 3D printing of lithium‐ion battery electrodes are studied. The
Pei Sun, Paul Vigneaux, Alejandro A. Franco   +2 more
wiley   +1 more source

Spectral gap of the Erlang A model in the Halfin-Whitt regime

Stochastic Systems, 2012
We consider a hybrid diffusion process that is a combination of two Ornstein-Uhlenbeck processes with different restraining forces. This process serves as the heavy-traffic approximation to the Markovian many-server queue with abandonments in the ...
Johan S.H. van Leeuwaarden, Charles Knessl   +1 more
doaj  

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet, Anna Largajolli, Petra M. Jauslin, Emilie Schindler, Mourad Hamimed, Wannee Kantasiripitak, Antonio Gonçalves, Eline Van Maanen, Khaled Benkali, Tomohisa Saito, Jonathan I. Silverberg, Andreas Wollenberg, Michael Graeber, Liliana Ulianov, Christophe Piketty, Luca Loprete, Vincent Duval, Nathalie Wagner   +17 more
wiley   +1 more source

Innovation Pathways to Carbon Efficiency: Disentangling the Effects of AI, R&D, and Clean Energy Blessings on U.S. Environmental Sustainability

Business Strategy and the Environment, EarlyView.
ABSTRACT The United States (U.S.) faces challenges in achieving its ambitious net‐zero carbon emissions target by 2050, with current emissions having fallen by less than 1% in 2024. Despite an investment of $500 billion in low‐carbon resources while holding the second‐largest green technology patent portfolio globally, it is further imperative to ...
Md Zubair Ahmad, Jewel Rana, Mohammad Fakhrul Islam, Md Nazmul Islam Jihad, Md. Rashed, Md. Kamal Uddin   +5 more
wiley   +1 more source

Performance of large virus removal filters during AAV processing: Influence of flux and process disruptions

Biotechnology Progress, EarlyView.
Abstract As adeno‐associated viral vectors (AAV) continue to advance through the clinical pipeline, effective downstream purification strategies must be developed to ensure bulk drug purity and safety. AAV are produced within mammalian cells, bringing forth risks associated with viral contamination.
Akshay S. Chaubal, Asingsa W. Arachchige, Annabelle J. Zahn, S. Ranil Wickramasinghe, Xianghong Qian, Andrew L. Zydney   +5 more
wiley   +1 more source

Histopathologic Analysis of the Morpho‐Functional Zones of the Human Acetabular Labrum

Clinical Anatomy, EarlyView.
ABSTRACT The structural and functional adaptation of soft tissues to mechanical load controls their ability to withstand injury and influences their capacity for healing. Similar to the knee meniscus, the acetabular labrum exhibits zonal differences in mechanical load distribution, resulting in distinct regions with unique structural and functional ...
Abdulaziz A. Alomiery, Andrew C. Hall, Thomas H. Gillingwater, Afaf Alsolami, Abduelmenem Alashkham   +4 more
wiley   +1 more source

An Asymptotic Analysis of Bivalent Monoclonal Antibody-Antigen Binding. [PDF]

Bull Math Biol
Heirene LA, Byrne HM, Yates JWT, Gaffney EA.   +3 more
europepmc   +1 more source

The Impact of Self‐Checkout Technology on Shopping Behavior in B2B Retail: Evidence From Point‐Of‐Sale Transaction Data

Journal of Consumer Behaviour, EarlyView.
ABSTRACT This study examines the impact of self‐checkout technology implementation on B2B customer shopping behavior using a novel methodological approach that combines propensity score matching with difference‐in‐differences analysis on actual point‐of‐sale transaction data.
Jindřich Špička, Michaela Dvořáková   +1 more
wiley   +1 more source