Results 181 to 190 of about 561,804 (322)

N‐of‐1 trials in clinical research: Methodological foundations, statistical approaches and implementation challenges

British Journal of Clinical Pharmacology, EarlyView.
N‐of‐1 trials offer a unique and rigorous methodology for evaluating individualized treatment responses, particularly within the context of personalized medicine. This article provides a comprehensive explanation of the conceptual and methodological underpinnings of N‐of‐1 trials, with particular emphasis on statistical techniques and considerations ...
Marcos Clint Leal De Carvalho, Matheus de Matos Dourado Simões, Ubiratan Cardinalli Adler, Antonio Brazil Viana Junior, Caren Nádia Soares de Sousa, Lia Lira Olivier Sanders   +5 more
wiley   +1 more source

Lévy Diffusion Under Power-Law Stochastic Resetting. [PDF]

Entropy (Basel)
Liu J, Li Y, Marchesoni F.
europepmc   +1 more source

On asymptotic behavior of work distributions for driven Brownian motion [PDF]

, 2015
Viktor Holubec, Dominik Lips, Artem Ryabov, Petr Chvosta, Philipp Maass   +4 more
openalex   +1 more source

Model‐informed drug development to support nemolizumab clinical development in adults and adolescents with moderate to severe atopic dermatitis

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Population pharmacokinetic (popPK) and pharmacokinetic‐pharmacodynamic (PK/PD) models were developed to support clinical development of nemolizumab, a humanized monoclonal antibody targeting the IL‐31 receptor α, in adolescents and adults with moderate‐to‐severe atopic dermatitis (AD).
Floris Fauchet, Anna Largajolli, Petra M. Jauslin, Emilie Schindler, Mourad Hamimed, Wannee Kantasiripitak, Antonio Gonçalves, Eline Van Maanen, Khaled Benkali, Tomohisa Saito, Jonathan I. Silverberg, Andreas Wollenberg, Michael Graeber, Liliana Ulianov, Christophe Piketty, Luca Loprete, Vincent Duval, Nathalie Wagner   +17 more
wiley   +1 more source

Quantum Unique Ergodicity and the Asymptotic Distribution of Nodal Domains on Hyperbolic Surfaces: A Transfinite Approach

Zen Revista, 10 MFC
openalex   +1 more source

Why we age

Biological Reviews, EarlyView.
ABSTRACT Three categories of explanations exist for why we age: mechanistic theories, which omit reference to evolutionary forces; weakening force of selection theories, which posit that barriers exist that prevent evolutionary forces from optimising fitness in ageing; and optimisation theories, which posit that evolutionary forces actually select for ...
Michael S. Ringel
wiley   +1 more source

Enhanced DEWMA-type control chart for process mean monitoring utilizing auxiliary information. [PDF]

Sci Rep
Masood S, Ibrar K, Movaheedi Z, Jabeen H.   +3 more
europepmc   +1 more source

Extreme eigenvalue distributions of Jacobi ensembles: New exact representations, asymptotics and finite size corrections

, 2019
Laureano Moreno‐Pozas, David Morales‐Jiménez, Matthew R. McKay   +2 more
openalex   +2 more sources

A universal approximate cross-validation criterion and its asymptotic distribution [PDF]

, 2012
Daniel Commenges, Cécile Proust‐Lima, Cécilia Samieri, Benoît Liquet   +3 more
openalex   +1 more source

Does ESG Investing Pay off? Comparing the Performance of ESG and Traditional ETFs Across European and US Markets

Business Strategy and the Environment, EarlyView.
ABSTRACT Investors have long recognized the importance of firms in promoting sustainability, leading to the rise of socially responsible investment (SRI). Specifically, there is a growing preference for exchange‐traded funds (ETFs) that prioritize environmental, social, and governance (ESG) principles.
Sandra Tenorio‐Salgueiro, Andrea Martínez‐Salgueiro, Rubén Lado‐Sestayo, Milagros Vivel‐Búa   +3 more
wiley   +1 more source