Results 141 to 150 of about 634,254 (363)

N‐of‐1 trials in clinical research: Methodological foundations, statistical approaches and implementation challenges

British Journal of Clinical Pharmacology, EarlyView.
N‐of‐1 trials offer a unique and rigorous methodology for evaluating individualized treatment responses, particularly within the context of personalized medicine. This article provides a comprehensive explanation of the conceptual and methodological underpinnings of N‐of‐1 trials, with particular emphasis on statistical techniques and considerations ...
Marcos Clint Leal De Carvalho, Matheus de Matos Dourado Simões, Ubiratan Cardinalli Adler, Antonio Brazil Viana Junior, Caren Nádia Soares de Sousa, Lia Lira Olivier Sanders   +5 more
wiley   +1 more source

Asymptotic Properties of a Statistical Estimator of the Jeffreys Divergence: The Case of Discrete Distributions

Mathematics
We investigate the asymptotic properties of the plug-in estimator for the Jeffreys divergence, the symmetric variant of the Kullback–Leibler (KL) divergence. This study focuses specifically on the divergence between discrete distributions. Traditionally,
Vladimir Glinskiy, Artem Logachov, Olga Logachova, Helder Rojas, Lyudmila Serga, Anatoly Yambartsev   +5 more
doaj   +1 more source

Asymptotic normality of p-norm estimators in multiple regression [PDF]

, 1984
Arjen E. Ronner
openalex   +1 more source

Why we age

Biological Reviews, EarlyView.
ABSTRACT Three categories of explanations exist for why we age: mechanistic theories, which omit reference to evolutionary forces; weakening force of selection theories, which posit that barriers exist that prevent evolutionary forces from optimising fitness in ageing; and optimisation theories, which posit that evolutionary forces actually select for ...
Michael S. Ringel
wiley   +1 more source

MLEce: Statistical inference for asymptotically efficient closed-form estimators in R

SoftwareX
Maximum likelihood estimation is a classical method with useful properties like efficiency, consistency, and asymptotic normality. However, the maximum likelihood estimator (MLE) cannot be in closed form in many distributions.
Jun Zhao, Yu-Kwang Kim, Yu-Hyeong Jang, Jae Ho Chang, Sang Kyu Lee, Hyoung-Moon Kim   +5 more
doaj   +1 more source

Asymptotic normality of improved weighted empirical distribution functions [PDF]

, 2005
Rostyslav Maiboroda, O. Kubaĭchuk
openalex   +1 more source

The Estimators of the Bent, Shape and Scale Parameters of the Gamma-Exponential Distribution and Their Asymptotic Normality [PDF]

, 2022
A. A. Kudryavtsev, О. В. Шестаков   +1 more
openalex   +1 more source

Does ESG Investing Pay off? Comparing the Performance of ESG and Traditional ETFs Across European and US Markets

Business Strategy and the Environment, EarlyView.
ABSTRACT Investors have long recognized the importance of firms in promoting sustainability, leading to the rise of socially responsible investment (SRI). Specifically, there is a growing preference for exchange‐traded funds (ETFs) that prioritize environmental, social, and governance (ESG) principles.
Sandra Tenorio‐Salgueiro, Andrea Martínez‐Salgueiro, Rubén Lado‐Sestayo, Milagros Vivel‐Búa   +3 more
wiley   +1 more source

Asymptotic normality of the test statistics for the unified relative dispersion and relative variation indexes. [PDF]

J Appl Stat, 2020
Touré AY, Dossou-Gbété S, Kokonendji CC.   +2 more
europepmc   +1 more source

Asymptotics for random effects models with serial correlation [PDF]

This paper considers the large sample behavior of the maximum likelihood estimator of random effects models. Consistent estimation and asymptotic normality as N and/or T grows large is established for a comprehensive specification which allows for serial
Jimmy Skoglund, Sune Karlsson
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