Results 191 to 200 of about 401,172 (292)

GlycoMAC: A Multiscale Metabolic‐Glycosylation Framework for Predicting Glycosylation Across Conditions in Mammalian Cell Cultures

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Antibody productivity and glycosylation quality in CHO cell cultures emerge from a dynamically evolving metabolic environment, yet existing models often work in isolation or at a single scale. Here, we present a multiscale mechanistic framework linking molecular, cellular, and macroscopic scales to predict how inputs shape bioprocess ...
Yuming Zeng, Sarah W. Harcum, Jinxiang Pei, Wei Xie   +3 more
wiley   +1 more source

IM-MetaLAB: the first digital laboratory for teaching the fundamental concepts of instrumentation and measurement in metaverse. [PDF]

Sci Rep
Bonavolontà F, Monaco A, Caputo E, Liccardo A.   +3 more
europepmc   +1 more source

Mechanistic Digital Model for Real‐Time Monitoring and Optimization of Adenovirus Production

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Adenoviral vectors are a critical vaccine platform, with billions of vaccine doses administered during the COVID‐19 pandemic. In addition, they are promising therapeutics for cancer treatment. To advance their manufacturing, real‐time monitoring of adenovirus production is essential for process optimization, yield improvement, and product ...
Xingge Xu, Daniel Rüdiger, Jeongbin Shin, Shawninder Chahal, Amine Kamen   +4 more
wiley   +1 more source

Energy-Aware Finite-Horizon MPC Coordination of Adaptive VSG Inertia and BESS Control for Transient-Stability Enhancement in Renewable-Dominated Low-Inertia Hybrid Microgrids. [PDF]

Sensors (Basel)
Rodríguez Romero JD, Hernández-Mayoral E, Gamboa SA, Torres-García V, Madrigal-Martínez M, Trujillo-Caballero JC, Jaramillo OA.   +6 more
europepmc   +1 more source

Evidence for adaptive explanations of semelparity in animals

Biological Reviews, EarlyView.
ABSTRACT Semelparity, the reproductive strategy of reproducing once, is widespread but uncommon in animals. Classes of models to explain the evolution of semelparity are based either on age structure and mortality schedules – demographic models in which high post‐reproductive mortality risk favours high reproductive effort and semelparity results from ...
Diana O. Fisher, Roberto Salguero‐Gómez   +1 more
wiley   +1 more source

Electric fields unlock a transient vulnerability window for vancomycin-based treatment of staphylococcal biofilms. [PDF]

Sci Rep
Balato M, Roscetto E, Petrarca C, Vitelli M, Aversa M, Galdiero U, Catania MR, Costanzo L, Soto SM, Mariconda M, Balato G.   +10 more
europepmc   +1 more source

Food‐solicitation displays in nestling birds: still begging for answers

Biological Reviews, EarlyView.
ABSTRACT Nestling begging is a key model for understanding animal communication and parent–offspring conflict. Dynamic begging displays are often interpreted as costly, honest signals of need, with honesty maintained by viability costs, as proposed in Godfray's influential signalling model.
Daniel Parejo‐Pulido, Tomás Redondo
wiley   +1 more source

Crowdsourcing Framework for Security Testing and Verification of Industrial Cyber-Physical Systems. [PDF]

Sensors (Basel)
Li Z, Ding Y, Zhao R, Wang S, Li J.
europepmc   +1 more source

Resolving the biome debate: ecological and palaeo‐data concur that the extensive tree‐limited grassy biomes of central and north‐western Madagascar are largely anthropogenic

Biological Reviews, EarlyView.
ABSTRACT For millennia, human activities have transformed ecosystems globally. Determining which landscapes are predominantly anthropogenic is crucial to conservation and habitat restoration. Madagascar, a critically‐threatened biodiversity hotspot, is a prominent example.
Grant S. Joseph, Sean Hixon, Colleen L. Seymour, Laurie R. Godfrey, Miguel Pedrono, Karen E. Samonds, Andrinajoro R. Rakotoarivelo, Brooke E. Crowley   +7 more
wiley   +1 more source

Simulating Partial Conduction Delays in VEPs Via Asynchronous and Contrast-Modulated Stimulation. [PDF]

Transl Vis Sci Technol
Pfeiffer LA, Haldina J, Heinrich SP.
europepmc   +1 more source