Results 1 to 10 of about 2,310 (147)

Integrated Immune, Epithelial and Lipid Pathways in NSAID-Exacerbated Respiratory Disease. [PDF]

Clin Transl Allergy
ABSTRACT NSAID‐exacerbated respiratory disease (N‐ERD) is a chronic inflammatory disorder characterized by asthma, chronic rhinosinusitis with nasal polyps and respiratory reactions to cyclooxygenase‐1 inhibiting nonsteroidal anti‐inflammatory drugs (NSAID).
Szatkowski P, Mastalerz L.
europepmc   +2 more sources

Comorbid Chronic Rhinosinusitis and Asthma: Shared Risk Factors and Treatment Implications-An EAACI Task Force Report. [PDF]

Allergy
ABSTRACT Chronic rhinosinusitis (CRS) and asthma are prevalent conditions that often coexist. These diseases share common inflammatory mechanisms, such as T‐helper cell 2 (T2)‐high inflammation, driven by interleukin (IL)‐4, IL‐5, and IL‐13 cytokines.
Toppila-Salmi S, Reitsma S, Hox V, Gane S, Gevaert P, Maza-Solano J, Helevä A, Sulku I, Santala K, Kangasniemi I, Klimek L, Chaker A, Karavelia A, Rudenko M, Pfaar O, Van Gerven L, Ariana S, Schiappoli M, Lundberg M, Hagemann J, Eguíluz-Gracia I, Moreira A.   +21 more
europepmc   +2 more sources

An acute aortic dissection prognostic score for predicting early in-hospital mortality in acute thoracic aortic dissection [PDF]

American Heart Journal Plus
Study objective: Acute thoracic aortic dissection (ATAD) has a high mortality rate. Factors that contribute to its onset include the environment, genetic factors, and infectious diseases. Recently, the presence of monocytes/macrophages has been suggested
Satoshi Kimura, Hiroaki Sato, Shohei Shimajiri, Toshiyuki Nakayama   +3 more
doaj   +2 more sources

Dupilumab-Related Adverse Events and Intolerance in Aspirin-Exacerbated Respiratory Disease Patients. [PDF]

Int Forum Allergy Rhinol
International Forum of Allergy &Rhinology, Volume 16, Issue 4, Page 413-417, April 2026.
Herpin LP, Bach R, Bruneto R, Faltas KA, Kohanski MA, Palmer JN, Adappa ND, Douglas JE, Bosso JV.   +8 more
europepmc   +2 more sources

A Narrative Review of Recent Developments in Aspirin Therapy After Desensitization in NSAIDs-Exacerbated Respiratory Disease [PDF]

Journal of Inflammation Research
Preena Ketan Patel,1 Aagat Sharma Khatiwada,2 Peter J Andrews,2,3 Glenis K Scadding,4 Alfonso Luca Pendolino1,21Department of Otolaryngology, Imperial College Healthcare NHS Trust, London, UK; 2Ear Institute, University College London (UCL), London, UK ...
Patel PK, Sharma Khatiwada A, Andrews PJ, Scadding GK, Pendolino AL   +4 more
doaj   +2 more sources

Decoding the Self: Single-Trial Prediction of Self-Boundary Meditation States From Magnetoencephalography Recordings. [PDF]

Hum Brain Mapp
Meditation‐induced self‐boundary dissolution can be predicted from magnetoencephalography recordings using Lempel‐Ziv complexity and oscillatory power as neural markers. We demonstrate significantly above‐chance classification of altered self‐experience on a single‐trial basis and show that it is mediated by complex activation patterns across brain ...
Röhr H, Atad DA, Trautwein FM, Mediano PAM, Dor-Ziderman Y, Schweitzer Y, Berkovich-Ohana A, Schmidt S, van Vugt MK.   +8 more
europepmc   +2 more sources

Biologics Reduce Symptoms of Alcohol Intolerance Better than Aspirin Desensitization in Patients with N-ERD and Nasal Polyps [PDF]

Biomedicines
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) exacerbated respiratory disease (N-ERD) is associated with chronic rhinosinusitis with nasal polyps (CRSwNP), asthma, and NSAID hypersensitivity.
Ulrike Foerster-Ruhrmann, Miroslav Jurkov, Agnieszka J. Szczepek, Karl-Christian Bergmann, Joachim W. Fluhr, Heidi Olze   +5 more
doaj   +2 more sources

Efficacy of Aspirin Therapy After Desensitization on Chronic Rhinosinusitis With Nasal Polyps Patients With Asthma and Non-steroidal Anti-inflammatory Drug Exacerbated Respiratory Disease -A Randomized Clinical Trial. [PDF]

Allergy
This randomized double‐blind clinical trial investigated the impact of aspirin therapy after desensitization in patients with CRSwNP, asthma, and N‐ERD. Various clinical outcomes were assessed, including health‐related quality of life (with the SNOT‐22 questionnaire) and the severity of nasal polyposis (with the NPS).
Helevä A, Lyly A, Salmi V, Mäkelä M, Kauppi P, Laulajainen-Hongisto A, Hafrén L, Virkkula P, Nuutinen M, Toppila-Salmi S.   +9 more
europepmc   +2 more sources

Is endoscopic sinus surgery sufficient to modify the evolution of adult AERD? Aspirin desensitization as a maintenance factor: systematic review [PDF]

Frontiers in Allergy, 2023
IntroductionAspirin desensitization (AD) and aspirin therapy after desensitization (ATAD) are therapeutic interventions for patients with aspirin-exacerbated respiratory disease (AERD).
Diego M. Conti, Eduardo J. Correa, Glenis K. Scadding, Glenis K. Scadding   +3 more
doaj   +2 more sources

Understanding brain donation decisions: Predictors of indecision and change over time from the Cleveland Alzheimer's Disease Research Center. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Little is known about factors influencing indecision or changes in brain donation program (BDP) enrollment status among Alzheimer's disease and related dementias research participants. This study examined demographic features associated with these decisions in participants from the Cleveland Alzheimer's Disease Research Center ...
Powell L, Silva D, Kovacevich A, Pillai J, Lynn A, Song S, Appleby BS.   +6 more
europepmc   +2 more sources