Comorbid Chronic Rhinosinusitis and Asthma: Shared Risk Factors and Treatment Implications-An EAACI Task Force Report. [PDF]
ABSTRACT Chronic rhinosinusitis (CRS) and asthma are prevalent conditions that often coexist. These diseases share common inflammatory mechanisms, such as T‐helper cell 2 (T2)‐high inflammation, driven by interleukin (IL)‐4, IL‐5, and IL‐13 cytokines.
Toppila-Salmi S +21 more
europepmc +2 more sources
An acute aortic dissection prognostic score for predicting early in-hospital mortality in acute thoracic aortic dissection [PDF]
Study objective: Acute thoracic aortic dissection (ATAD) has a high mortality rate. Factors that contribute to its onset include the environment, genetic factors, and infectious diseases. Recently, the presence of monocytes/macrophages has been suggested
Satoshi Kimura +3 more
doaj +2 more sources
Dupilumab-Related Adverse Events and Intolerance in Aspirin-Exacerbated Respiratory Disease Patients. [PDF]
International Forum of Allergy &Rhinology, Volume 16, Issue 4, Page 413-417, April 2026.
Herpin LP +8 more
europepmc +2 more sources
Decoding the Self: Single-Trial Prediction of Self-Boundary Meditation States From Magnetoencephalography Recordings. [PDF]
Meditation‐induced self‐boundary dissolution can be predicted from magnetoencephalography recordings using Lempel‐Ziv complexity and oscillatory power as neural markers. We demonstrate significantly above‐chance classification of altered self‐experience on a single‐trial basis and show that it is mediated by complex activation patterns across brain ...
Röhr H +8 more
europepmc +2 more sources
Biologics Reduce Symptoms of Alcohol Intolerance Better than Aspirin Desensitization in Patients with N-ERD and Nasal Polyps [PDF]
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) exacerbated respiratory disease (N-ERD) is associated with chronic rhinosinusitis with nasal polyps (CRSwNP), asthma, and NSAID hypersensitivity.
Ulrike Foerster-Ruhrmann +5 more
doaj +2 more sources
Efficacy of Aspirin Therapy After Desensitization on Chronic Rhinosinusitis With Nasal Polyps Patients With Asthma and Non-steroidal Anti-inflammatory Drug Exacerbated Respiratory Disease -A Randomized Clinical Trial. [PDF]
This randomized double‐blind clinical trial investigated the impact of aspirin therapy after desensitization in patients with CRSwNP, asthma, and N‐ERD. Various clinical outcomes were assessed, including health‐related quality of life (with the SNOT‐22 questionnaire) and the severity of nasal polyposis (with the NPS).
Helevä A +9 more
europepmc +2 more sources
Is endoscopic sinus surgery sufficient to modify the evolution of adult AERD? Aspirin desensitization as a maintenance factor: systematic review [PDF]
IntroductionAspirin desensitization (AD) and aspirin therapy after desensitization (ATAD) are therapeutic interventions for patients with aspirin-exacerbated respiratory disease (AERD).
Diego M. Conti +3 more
doaj +2 more sources
Alzheimer's Disease in Ghanaian Medical Education: Investigating the Effect of Curriculum Changes on Student Perceptions and Attitudes [PDF]
Abstract Background Alzheimer's disease is a progressive neurodegenerative disorder with significant public health implications. In Ghana, limited awareness among healthcare professionals often delays diagnosis and care. Medical students are crucial to addressing this gap, yet their training on AD remains inadequate.
Abukuri D.
europepmc +2 more sources
Understanding brain donation decisions: Predictors of indecision and change over time from the Cleveland Alzheimer's Disease Research Center. [PDF]
Abstract INTRODUCTION Little is known about factors influencing indecision or changes in brain donation program (BDP) enrollment status among Alzheimer's disease and related dementias research participants. This study examined demographic features associated with these decisions in participants from the Cleveland Alzheimer's Disease Research Center ...
Powell L +6 more
europepmc +2 more sources
Study protocol for a randomized double-blinded placebo-controlled trial on ASA therapy for patients with chronic rhinosinusitis with nasal polyps, NSAID-exacerbated respiratory disease, and asthma [PDF]
BackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory condition affecting the nasal passages and paranasal sinuses. It is characterized by persistent inflammation and often leads to a considerable decline in health-related
Sanna Toppila-Salmi +23 more
doaj +2 more sources

