Results 121 to 130 of about 35,381 (234)
Ataxia-telangiectasia A guide for parents
SIGLEAvailable from British Library Document Supply Centre-DSC:f99/2755 / BLDSC - British Library Document Supply CentreGBUnited ...
Ataxia-Telangiectasia Society, Harpenden (United Kingdom)
core
Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu +3 more
wiley +1 more source
Betamethasone Treatment Of Ataxia-Telangiectasia
The response to corticosteroid therapy in a 3-year-old boy with ataxia-telangiectasia is reported from University of Siena ...
J Gordon Millichap
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Endometrial cancer (EC), a major gynecologic malignancy and a representative “cold tumor”, exhibits a tumor immune microenvironment (TIME) influenced by a broad range of cellular and molecular elements, immunosuppressive signals, and pathways of immune evasion.
Jingxuan Ye +4 more
wiley +1 more source
Peripheral Neuropathy in Ataxia-Telangiectasia
EMG examinations performed on 32 children aged three to 13 years with ataxia-telangiectasia are reported from the Neurological Department of the Child Health Centre, Warsaw ...
J Gordon Millichap
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Nerve Ultrasound Detects Peripheral Nerve Enlargement in Cerebrotendinous Xanthomatosis
ABSTRACT Introduction/Aims Cerebrotendinous xanthomatosis (CTX) is a rare autosomal recessive disorder caused by variants in the CYP27A1 gene, resulting in cholestanol accumulation in various tissues, including peripheral nerves. Polyneuropathy is common but often under‐recognized in CTX.
Antonio Edvan Camelo‐Filho +8 more
wiley +1 more source
Human Absorption, Metabolism, and Excretion (hAME) Mass Balance Studies in Patients With Cancer
ABSTRACT Radiolabeled mass balance human studies are a critical component of clinical pharmacology programs supporting the development of new investigational drugs. These studies provide information about absorption, metabolism, and excretion (AME) of the parent drug and metabolite(s) in the human body and are normally conducted in healthy volunteers ...
Begoña de las Heras +9 more
wiley +1 more source
ABSTRACT Primary refractory Diffuse Large B‐Cell Lymphoma is associated with poor outcomes and limited responsiveness to conventional salvage therapies. Although CAR T‐cell therapy represents the standard of care in this setting, a substantial proportion of patients cannot receive it despite meeting disease‐related criteria. In this review, “unsuitable”
Santino Caserta +12 more
wiley +1 more source
Recent reports from a number of laboratories have linked radiosensitivity in ataxia telangiectasia (A-T) to a large and prolonged block of some cells in G2 phase.
Lavin, Martin F., Bates Paul R.
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