Development and validation of a stability-indicating RP–HPLC method for estimation of atazanavir sulfate in bulk [PDF]
Journal of Pharmaceutical Analysis, 2017 A stability-indicating reverse phase–high performance liquid chromatography (RP–HPLC) method was developed and validated for the determination of atazanavir sulfate in tablet dosage forms using C18 column Phenomenix (250 mm×4.6 mm, 5 μm) with a mobile ...
P N Murthy
exaly +6 more sources
Trace Level Determination of Mesityl Oxide and Diacetone Alcohol in Atazanavir Sulfate Drug Substance by a Gas Chromatography Method [PDF]
Scientia Pharmaceutica, 2016 A capillary gas chromatography method with a short run time, using a flame ionization detector, has been developed for the quantitative determination of trace level analysis of mesityl oxide and diacetone alcohol in the atazanavir sulfate drug substance.
Hemant Kumar Sharma
exaly +5 more sources
Spectrophotometric method for determination of atazanavir sulfate in capsule dosage form
Quimica Nova, 2011 Two sensitive and simple spectrophotmetric methods were developed for determination of Atazanavir Sulfate in capsule dosage form. The first method was based on the oxidative coupling of ATV with 3-Methyl Benzothiazolin-2-one hydrazone (MBTH).
Anindita Behera
exaly +5 more sources
Development and validation of a UPLC-MS method for determination of atazanavir sulfate by the “analytical quality by design” approach [PDF]
Acta Pharmaceutica, 2020 A UPLC-MS method for the estimation of atazanavir sulfate was developed using the “analytical quality by design” approach. The critical chromatographic quality attributes identified were retention time, theoretical plates and peak tailing.
Saha Chandni +2 more
doaj +4 more sources
Mechanistic in vitro studies indicate that the clinical drug–drug interactions between protease inhibitors and rosuvastatin are driven by inhibition of intestinal BCRP and hepatic OATP1B1 with minimal contribution from OATP1B3, NTCP and OAT3 [PDF]
Pharmacology Research & Perspectives, 2023 Previous use of a mechanistic static model to accurately quantify the increased rosuvastatin exposure due to drug–drug interaction (DDI) with coadministered atazanavir underpredicted the magnitude of area under the plasma concentration–time curve ratio ...
Robert Elsby +5 more
doaj +2 more sources
Development, Validation and Statistical Correlation of RP–LC Methods for Determination of Atazanavir Sulfate in Capsule Dosage Form [PDF]
E-Journal of Chemistry, 2012 To study the effective therapeutic bioavailability of Atazanavir Sulfate (ATV), administered singly or in combination with Ritonavir, a cost effective and rapid method is required.
A. Behera +3 more
doaj +2 more sources
Kidney disease among adults on tenofovir-based second-line antiretroviral therapy in Dar es Salaam, Tanzania [PDF]
Southern African Journal of HIV MedicineBackground: Kidney disease is a growing non-AIDS-related comorbidity among people living with HIV (PLWH). Tenofovir disoproxil fumarate (TDF) can result in proximal tubulopathy and acute tubular injury, whereas atazanavir/ritonavir (ATV/r) can cause ...
Sabina F. Mugusi +6 more
doaj +2 more sources
Drug Development and Therapeutics, 2015 Background: Ritonavir (RTV) and atazanavir sulfate (ATV) are protease inhibitor and RTV mostly used as a booster for increasing the bioavailability of other protease inhibitors like ATV. Aims: Quality assessment of the new dosage form of RTV and ATV i.e., tablets is very essential and hence this work deals with to develop sensitive, simple and ...
DishaA Patel +2 more
exaly +2 more sources
Current Issues in Molecular Biology, 2022 Candida albicans is the chief etiological agent of candidiasis, a mycosis prevalent in individuals with acquired immunodeficiency syndrome (AIDS). In recent years, the introduction of human immunodeficiency virus (HIV) protease inhibitors (HIV-PI) has ...
Juliana de C. Fenley +5 more
doaj +1 more source