Results 91 to 100 of about 25,250 (249)

Evidence map and gap analysis of metabolic change in pediatric growth hormone deficiency treated with growth hormone

Pediatric Investigation, EarlyView.
This evidence map of 63 studies (n = 6158) showed growth hormone therapy in children with growth hormone deficiency has neutral glucose effects, mixed lipid outcomes, potential benefits for bone mineral density, bone mineral content, and parathyroid hormone, but generally no impact on thyroid function, body composition, or body mass index.
Wei Wu, Ningyi Song, Yue Zhao, Caiqi Du, Yuning Zhao, You Wu, Xiaoping Luo   +6 more
wiley   +1 more source

Atherogenic Index of Plasma [Log(Triglycerides/HDL-Cholesterol)]: Theoretical and Practical Implications [PDF]

Clinical Chemistry, 2004
In individuals with type 2 diabetes, metabolic syndrome, and the combined dyslipidemia, cardiovascular risk is increased by a clustering of risk factors such as abdominal obesity, impaired fasting glucose, increased blood pressure, low HDL-cholesterol (HDL-C), increased triglycerides (TGs), and an increase in small, dense LDL particles.
openaire   +2 more sources

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

Association of inflammation mediated blood heavy metals with plasma atherogenic index: NHANES analysis 2015–2020

Ecotoxicology and Environmental Safety
Metal pollutants are widespread in various environments, and numerous studies have indicated an association between metal exposure and the risk of atherosclerosis. However, the underlying mechanisms of this association remain unclear.
Xue Wang
doaj   +1 more source

Contradictory links between lipid levels and bone health: atherogenic index of plasma and bone microarchitecture

Journal of Orthopaedic Surgery and Research
Lipids increase osteoporosis and fracture risk, yet research on Atherogenic Index of Plasma (AIP), bone mineral density declines (BMD), and trabecular bone score (TBS) is limited.
Bo Xu, Guoliang Ma, Xin Chen, Bowen Yang, Dian Zhang, Xiao-Kuan Qin, Taiwei Lou, Weili Duan, Le Yu, Minshan Feng, He Yin, Xu Wei, Li-Guo Zhu   +12 more
semanticscholar   +1 more source

Prognostic value of atherogenic index of plasma in pulmonary hypertension

Frontiers in Medicine
BackgroundThe atherogenic index of plasma (AIP) is a brand-new lipid parameter that has been used to assess various cardiovascular events. This study aimed to investigate the prognostic value of AIP in patients with pulmonary hypertension (PH).MethodsThis retrospective study was conducted at Shanghai Jiao Tong University School of Medicine affiliated ...
Meng-Qi Chen, An Wang, Chuan-Xue Wan, Bin-Qian Ruan, Jun Tong, Jie-Yan Shen   +5 more
openaire   +2 more sources

Comparison of Biocompatibility and Efficacy of Regional Citrate Anticoagulation and Unfractionated Heparin During Expanded Hemodialysis With a Medium Cut‐Off Membrane—A Randomized Trial

Artificial Organs, EarlyView.
In a randomized cross‐over trial, regional citrate anticoagulation provided superior biocompatibility over full‐dose unfractionated heparin during expanded hemodialysis with significantly lower activation of complement, granulocytes, and platelets without affecting dialysis efficiency. ABSTRACT Background Regional citrate anticoagulation (RCA) improves
Marija Malgaj Vrečko, Jernej Pajek, Jakob Gubenšek, Samo Hudoklin, Joško Osredkar, Mojca Božič Mijovski, Aleš Jerin, Jadranka Buturović‐Ponikvar   +7 more
wiley   +1 more source

High Prevalence of Metabolic Dysfunction–Associated Steatohepatitis With Significant Fibrosis in Primary Care and Endocrinology Clinics

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Metabolic dysfunction‐associated steatohepatitis (MASH) is a leading cause of cirrhosis. NIS2+ is a recently approved serum‐based test combining two biomarkers (miR‐34a‐5p and YKL‐40) to identify at‐risk MASH (i.e., MASH and significant fibrosis). Objective To assess the prevalence of at‐risk MASH by NIS2+ in individuals from primary care
Srilaxmi Kalavalapalli, Eddison Godinez Leiva, Andrea Ortiz Rocha, Anu Sharma, Diana Barb, Nathaly Cuervo‐Pardo, Kelly Y. Chun, Toni R. Prezant, Margery A. Connelly, Jens T. Rosenberg, Joseph R. Grajo, Fernando Bril, Kenneth Cusi   +12 more
wiley   +1 more source

Association of myeloperoxidase and the atherogenic index of plasma in children with end-stage renal disease [PDF]

Journal of Medical Biochemistry, 2017
Background: The aim of this study was to explore oxidative stress status, especially the enzyme myeloperoxidase in children with end-stage renal disease.
Ristovski-Kornic Danijela, Stefanović Aleksandra, Kotur-Stevuljević Jelena, Zeljković Aleksandra, Spasojević-Kalimanovska Vesna, Vekić Jelena, Miljković Milica, Paripović Dušan, Peco-Antić Amira, Jelić-Ivanović Zorana   +9 more
doaj  

ADAM17 and its proteolytic targets in disease pathogenesis

The FEBS Journal, EarlyView.
ADAM17 as a multifunctional sheddase with contrasting roles across inflammatory, metabolic, cardiovascular, and neoplastic diseases. Through regulated activation by iRhom, iTAP/FRMD8, and tetraspanins, ADAM17 cleaves diverse membrane ligands and receptors, thereby promoting inflammation, fibrosis, obesity, insulin resistance, and tumor progression ...
Abdulbasit Amin, Marina Badenes
wiley   +1 more source