Results 61 to 70 of about 166,779,119 (261)

Integrative Omics Analysis Reveals a CD206+ Macrophage/Dendritic Cell–CD155–TIGIT+ Regulatory T Cell Axis as a Protective Immune Checkpoint Pathway in Atherosclerosis Progression

Barrier Immunity, EarlyView.
ABSTRACT RNA sequencing (RNA‐seq) analysis revealed transcriptional features indicative of sustained immunosuppression within regulatory T cells (Tregs) isolated from atherosclerotic tissues, highlighting the critical contribution of immune checkpoint (ICP) receptor–ligand interactions to atherosclerosis progression. To comprehensively characterize the
Ying Shao, Fatma Saaoud, Mohammed Ben Issa, Keman Xu, Yifan Lu, Shih‐Yu Hung, Juanjuan Liu, Bo Yuan, Juncheng Wei, Sheng Wu, Sadia Mohsin, Zhengjie Zhou, Beata Kosmider, Laisel Martinez, Roberto Vazquez‐Padron, Hong Wang, Xiaofeng Yang   +16 more
wiley   +1 more source

Association of the atherogenic index of plasma and bilirubin–lipid composite index with coronary stenosis in patients residing in high-altitude regions

Journal of International Medical Research
Background This study examined the relationship of patients’ sex, age, body mass index, history of hypertension, various lipid indices, atherogenic index of plasma, bilirubin–lipid composite index 1, and bilirubin–lipid composite index 2 with the degree ...
Yiwen Zhang, Rundong Xia, Youlu Shen, Ming Ren   +3 more
doaj   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

HUBUNGAN ANTARA GLYCATED ALBUMIN DENGAN ATHEROGENIC INDEX PLASMA PADA PASIEN DIABETES MELITUS TIPE 2 [PDF]

, 2015
Latar belakang: Atherosclerosis pada diabetes melitus tipe 2 melibatkan banyak faktor antara lain hiperglikemia dan hiperlipidemia. Kontrol glukosa darah pasien diabetes melitus akhir-akhir ini menggunakan glycated albumin karena ...
Simamora, Irwan
core  

LIPID SPECTRUM IN PATIENTS WITH ESSENTIAL ARTERIAL HYPERTENSION AND HEALTHY PEOPLE WITH DIFFERENT NOS2 GENE ALLELIC VARIATIONS

Transactions of the Karelian Research Centre of the Russian Academy of Sciences, 2020
The plasma lipid profile was analyzed in healthy people and patients with essential arterial hypertension (EAH) (stages I–II) with different allelic variations in the inducible nitric oxide synthase (NOS2) gene polymorphic markers (rs1800482 and ...
Ludmila Topchieva, Viktoria Korneva, Olga Balan, Irina Malysheva, Irina Kurbatova   +4 more
doaj   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Comparative Prognostic Value of CHA2DS2-VASc Score and Atherogenic Plasma Index for One-year Mortality Prediction in Ischemic Stroke Patients [PDF]

Objective: The CHA₂DS₂-VASc (congestive heart failure, hypertension, age ≥75 years, diabetes mellitus, stroke, vascular disease, age, female gender) score is significantly associated with poor outcomes after ischemic stroke.
Muzaffer Aslan, Yunus Emre Yavuz, Doğaç Okşen   +2 more
core   +1 more source

The correlation of plasma atherogenic index and obesity in patients with familial Mediterranean fever

, 2022
Background The plasma atherogenic index (PAI) is associated with cardiovascular diseases. This study evaluated the relationship between PAI and obesity in patients with familial Mediterranean fever (FMF) and its advantage over conventional lipid ...
Gogebakan, Hasan, Hasan Göğebakan, KAŞALİ, Kamber, Kamber Kaşali   +3 more
core   +1 more source

Associations of the atherogenic index of plasma with insulin resistance and inflammation

Revista da Associação Médica Brasileira
This study aimed to investigate the association between the atherogenic index of plasma and insulin resistance, while also evaluating atherogenic index of plasma's prognostic value in inflammation by examining its correlation with platelet/lymphocyte ratio and neutrophil/lymphocyte ratio.Data collection involved accessing records from January 2022 to ...
Yasin Altun, Halime Dilber Balcı, Nilay Çom Aybal   +2 more
openaire   +3 more sources

Nutritional, Functional, and Anti‐Hypercholesterolemic Properties of Sourdough Breads From Unripe Plantain, Tiger Nut, and Fenugreek Flours

Food Chemistry International, EarlyView.
Composite sourdough breads were developed from blends of unripe plantain, tiger nut, and fenugreek flours. Optimized formulations improved pasting stability and enhanced texture, producing softer more elastic crumbs. The enriched breads contained higher dietary fiber and bioactive compounds, and significantly reduced serum cholesterol markers ...
Mary T. Ademosun, Olufunmilayo S. Omoba, Ganiyu Oboh, Adedamola I. Akinyede, Rukayat O. Awolola   +4 more
wiley   +1 more source