Results 61 to 70 of about 25,250 (249)

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

Chronic Diseases and Translational Medicine, EarlyView.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves, Masatoki Teranishi, Rajendranandini Majumdar, Fazal Khan, Mohan Dodeja, Ana Claudia Teixeira de Castro Gonçalves Ortega, Marco Acerboni, Arosh S. Perera Molligoda Arachchige, Frank James   +8 more
wiley   +1 more source

The effect of eight weeks of high-intensity interval training on changes in atherogenic parameters and liver enzymes in patients with non-alcoholic fatty liver [PDF]

فصلنامه ابن سینا, 2021
Background and aims: Non-alcoholic fatty liver disease (NAFLD) is a chronic liver condition that is associated with the changes in transferase enzymes and atherogenic parameters.
Bahloul Ghorbanian, Yousef Saberi, Shahla Babaloyan   +2 more
doaj  

Association between atherogenic index of plasma control level and incident cardiovascular disease in middle-aged and elderly Chinese individuals with abnormal glucose metabolism

Cardiovascular Diabetology
The atherogenic index of plasma (AIP) and cardiovascular disease (CVD) in participants with abnormal glucose metabolism have been linked in previous studies.
Qianqian Min, Zhigang Wu, Jiangnan Yao, Siyi Wang, Lanzhi Duan, Sijia Liu, Mei Zhang, Yanhong Luo, Dongmei Ye, Yuxu Huang, Lan Chen, Ke Xu, Jianghua Zhou   +12 more
semanticscholar   +1 more source

Evaluation of atherogenic index of plasma levels at hypertensive patients

Archives of Clinical and Experimental Medicine, 2019
Aim: Hypertension is a major risk factor for cardiovascular system. Recent studies showed that atherogenic index of plasma (AIP) has a strong association with cardiovascular morbidity, all-cause mortality, atherosclerosis and severity of coronary artery disease. It also has a relationship with endothelial damage in hypertensive patients.
Özge TURGAY YILDIRIM, Ercan AKŞİT, Fatih AYDIN, Ayşe HÜSEYİNOĞLU AYDIN   +3 more
openaire   +4 more sources

Causal Effects of Hydrophilic Bile Acids on Carfilzomib‐Related Cardiovascular Events in Multiple Myeloma: A Mendelian Randomization Study

Clinical Pharmacology &Therapeutics, EarlyView.
Carfilzomib is highly effective in the treatment of multiple myeloma, but it has been associated with cardiovascular adverse events that impact patient outcomes. Our prior global metabolomic analyses indicated an association between hydrophilic bile acids and carfilzomib‐cardiotoxicity risk, although a causal relationship remained to be determined ...
Samia Shabnaz, Eric Farber‐Eger, Marwa Tantawy, Neyousha Shahisavandi, Timothy J. Garrett, Samuel M. Rubinstein, Michael G. Fradley, Mohammed E. Alomar, Danny DeAvila, Kenneth H Shain, R. Frank Cornell, Daniel Lenihan, Qing Lu, Quinn S Wells, Rachid C. Baz, Yan Gong   +15 more
wiley   +1 more source

The association of atherogenic index of plasma with cardiovascular outcomes in patients with coronary artery disease: A systematic review and meta-analysis

Cardiovascular Diabetology
Atherogenic index of plasma (AIP) represents a novel marker in the current era of cardiovascular diseases. In this meta-analysis, we aimed to evaluate the association of AIP with cardiovascular prognosis in patients with coronary artery disease (CAD ...
Mehrdad Rabiee Rad, Ghazal Ghasempour Dabaghi, Bahar Darouei, Reza Amani-Beni   +3 more
semanticscholar   +1 more source

Relationship between the cumulative exposure to atherogenic index of plasma and ischemic stroke: a retrospective cohort study

Cardiovascular Diabetology, 2023
Background Atherogenic index of plasma (AIP) has been demonstrated as a surrogate marker for ischemic stroke, but there is limited evidence for the effect of long-term elevation of AIP on ischemic stroke.
Huancong Zheng, Kuangyi Wu, Weiqiang Wu, Guanzhi Chen, Zekai Chen, Z. Cai, Zhiwei Cai, Yulong Lan, Shou-lin Wu, Youren Chen   +9 more
semanticscholar   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Associations of the triglyceride-glucose index and atherogenic index of plasma with the severity of new-onset coronary artery disease in different glucose metabolic states

Cardiovascular Diabetology
The triglyceride-glucose (TyG) index is considered a dependable biomarker for gauging insulin resistance. The atherogenic index of plasma (AIP) represents a marker reflecting atherosclerosis.
Xiaosheng Wu, Weiping Qiu, Huancheng Yang, Yan-Jun Chen, Jianling Liu, Guojun Zhao   +5 more
semanticscholar   +1 more source

Pioglitazone Reduces Atherogenic Index of Plasma in Patients with Type 2 Diabetes [PDF]

Clinical Chemistry, 2004
AbstractBackground: Insulin resistance is often associated with increased triglyceride (TG) and decreased HDL-cholesterol (HDL-C) concentrations and increased small LDL particles. The Atherogenic Index of Plasma (AIP), defined as log(TG/HDL-C), has recently been proposed as a marker of plasma atherogenicity because it is increased in people at higher ...
Meng H, Tan, Don, Johns, N Bradly, Glazer   +2 more
openaire   +2 more sources