Results 211 to 220 of about 751,086 (339)

Macrophage Derived Galectin‐3 Promotes Renal Fibrosis and Diabetic Kidney Disease by Enhancing TGFβ1 Signaling

open access: yesAdvanced Science, EarlyView.
Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen   +17 more
wiley   +1 more source

Neutrophil–Endothelium Interaction Mediated by S100A9 Promotes Pulmonary Vascular Remodeling During Pulmonary Hypertension

open access: yesAdvanced Science, EarlyView.
This study investigates the critical mechanisms underlying pulmonary hypertension progression, with a focus on the novel role of neutrophil‐derived S100A9 in endothelial dysfunction‐mediated pulmonary vascular remodeling. By integrating human lung samples, multi‐omics analyses, animal models, and mechanistic in vitro studies, it is revealed that how ...
Yu Guo   +13 more
wiley   +1 more source

A Longitudinal Study Reveals Metabolomic Markers for Individuals at Risk, Disease Severity, and Treatment Response in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
This study investigates plasma metabolomic biomarkers for rheumatoid arthritis (RA) development using longitudinal data from 209 RA patients and 56 individuals at risk. It also reveals metabolic signatures linked to severity, age, sex, and anti‐citrullinated protein autoantibody in RA.
Chenxi Zhu   +21 more
wiley   +1 more source

Clinicopathologic Correlations in Coronary Atherosclerosis [PDF]

open access: bronze, 1963
Robert Allison   +6 more
openalex   +1 more source

Unveiling Macrophage Content as a Predictive Biomarker for Intraoperative ICG Imaging Efficacy in Lung Cancer

open access: yesAdvanced Science, EarlyView.
Indocyanine Green (ICG)‐guided lung cancer surgery efficacy varies significantly among patients. This study identifies tumor macrophage content as a predictive biomarker. Macrophages are primary ICG reservoirs, storing seven‐fold more ICG than cancer cells.
Yue Yan   +13 more
wiley   +1 more source

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