Results 301 to 310 of about 782,334 (339)

CYP2C19 genotype testing for clopidogrel: A guideline developed by the UK Centre of Excellence for regulatory science and innovation in pharmacogenomics (CERSI‐PGx)

British Journal of Clinical Pharmacology, EarlyView.
Clopidogrel, an antiplatelet agent, is currently licensed in the United Kingdom for the prevention and treatment of atherothrombotic events in cerebrovascular disease, coronary artery disease and peripheral arterial disease. Clopidogrel requires metabolic activation by the cytochrome P450 enzyme CYP2C19 to be effective.
Cinzia Dello Russo, Iain Frater, Rebecca Kuruvilla, Stefanie Lip, Hannah O'Neill, Kerry Burke, Vicky Chaplin, Alexander S. F. Doney, Salim Elyas, Nicholas Greaves, Sophie Harding, David Hargroves, Judith Hayward, Dyfrig A. Hughes, Tom A. T. Hughes, Sree Kondapally, Patrick Mok, Aaron Peace, Imran Rafi, Simon Ray, Vicky Stinton, Luigi Venetucci, Munir Pirmohamed   +22 more
wiley   +1 more source

Low Liver Enzymes and Risk of Dementia: The Atherosclerosis Risk in Communities (ARIC) Study

Yunfei Lu, James Russell Pike, Elizabeth Selvin, Thomas H. Mosley, Priit Palta, A.R Sharrett, Alvin G. Thomas, Laura R. Loehr, A. Sidney Barritt, Ron C. Hoogeveen, Gerardo Heiss   +10 more
openalex   +1 more source

TNF superfamily molecules in atherosclerosis: mechanistic insights and therapeutic translation. [PDF]

Front Immunol
Luo J, Zhang J, Xie Y, Wu M, Wang Z, Ma D.   +5 more
europepmc   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Journal of Lipid and Atherosclerosis Update 2025

Ji Hye Heo, In‐Kyung Jeong
openalex   +1 more source

Pgk1 activation restores endothelial metabolic homeostasis to alleviate vascular aging and atherosclerosis. [PDF]

Cardiovasc Diabetol
Lu J, Wang J, Liu Y, Zhang C, Zhang G, Ge Y, Liu L.   +6 more
europepmc   +1 more source

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

BMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu, Chung Yin Matthew Cheung, Liling Liu, Hoi Pan Harry Cheung, Kam Yu Tam, Dai Fei Elmer Ker, Sarah H. Cartmell, Chuanbin Mao, Zhiyong Zhang, Dan Michelle Wang   +9 more
wiley   +1 more source

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Femoral artery plaque: A simple ultrasound clue for severe coronary stenosis. [PDF]

World J Cardiol
Gumanova NG, Vasilyev DK, Mols AAA, Drapkina OM, Kiselev AR.   +4 more
europepmc   +1 more source

Phenotype-specific associations of circulating adipokine levels with carotid atherosclerosis: a systematic review and meta-analysis. [PDF]

Int J Cardiol Cardiovasc Risk Prev
Yang S, Shen H, You Y, Fu Z, Guo S, Zhang Y, Liu Q, Yang Y, Li Y, Qin J, Liu P.   +10 more
europepmc   +1 more source