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Leukotrienes and Atherosclerosis

Current Drug Targets, 2010
Evidence from experimental and genetic studies suggest the existence of a potential link between the leukotrienes (LT) signalling cascade, and the pathogenesis/progression of atherosclerosis and its serious consequences such as acute myocardial infarction (AMI), stroke, aortic aneurysms, and intimal hyperplasia.
G. Riccioni, M. Bäck, V. Capra
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Atherosclerosis, biomarkers of atherosclerosis and Alzheimer's disease

International Journal of Neuroscience, 2013
Alzheimer's disease (AD) is the most prevalent type of dementia, involving progressive deterioration of neuronal networks. Although the pathophysiological mechanism of AD is not fully elucidated, apart from β-amyloid and tau protein, a diverse number of factors such as cardiovascular risk factors, inflammation, and lipids metabolism may play a ...
Aidonio, Fiolaki   +5 more
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THROMBOSIS AND ATHEROSCLEROSIS

British Medical Bulletin, 1978
From the clinical point of view the most important end results of atherosclerosis are stenosis and occlusion of the affected artery. A prerequisite for this is a degree of plaque growth sufficient to encroach significantly on the integrity of the vessel lumen.
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Platelets and atherosclerosis

Journal of Atherosclerosis Research, 1964
Summary The evidence which has been discussed shows the following. (1) There is a relationship between the sites at which thrombi occur in models of vessel configurations in extracorporeal shunts and the sites of early atherosclerosis. (2) Platelet-rich microthrombi occur on apparently normal endothelium in the distribution of the early ...
J F, MUSTARD   +3 more
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Atherosclerosis in alcoholics

Forensic Science International, 1995
A cohort of alcoholics who underwent a medico-legal autopsy during a 5-year period was compared with non-alcoholic controls who did not differ from the alcoholics in selection criteria. The degree of atherosclerosis in the coronary arteries and the aorta was examined.
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Arsenic and atherosclerosis

Atherosclerosis, 2000
Epidemiological studies have demonstrated a correlation between environmental or occupational arsenic exposure and a risk of vascular diseases related to atherosclerosis. Studies summarized in this review suggest that arsenic induces endothelial dysfunction, including inflammatory and coagulating activity as well as impairs nitric oxide (NO) balance ...
Petia P, Simeonova, Michael I, Luster
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Taurine and atherosclerosis

Amino Acids, 2012
Taurine is abundantly present in most mammalian tissues and plays a role in many important physiological functions. Atherosclerosis is the underlying mechanism of cardiovascular disease including myocardial infarctions, strokes and peripheral artery disease and remains a major cause of morbidity and mortality worldwide.
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Atherosclerosis and clinical atherosclerosis

2011
Atherosclerotic cardiovascular diseases are the major cause of mortality for both men and women in the industrial as well as the developing world, with the majority of deaths occurring in developing countries [1,2]. In addition, diseases due to atherosclerosis such as coronary artery disease (CAD) causing coronary heart disease (CHD), cerebrovascular ...
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The pathogenesis of atherosclerosis

International Journal of Cardiology, 1997
The hypothesis that atherosclerosis is a 'response to injury' is now generally accepted. This paper briefly reviews factors that can damage the vascular endothelium plus the formation of fatty streak lesions, thrombogenic surfaces, fibrous plaques and complex advanced lesions of atherosclerosis.
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