Results 261 to 270 of about 185,884 (310)
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Atherosclerotic Cardiovascular Disease in Diabetes Patients
Current Diabetes Reviews, 2023Background: Diabetes mellitus (DM) is a metabolic disorder characterized by abnormally elevated levels of blood glucose. The hyperglycemic condition is caused by abnormalities in either insulin secretion, insulin action, or both. Two-thirds of diabetes-related deaths are caused by atherosclerotic cardiovascular disease (ASCVD).
Rina Amelia +3 more
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Imaging of atherosclerotic cardiovascular disease
Nature, 2008Atherosclerosis is characterized by thickening of the walls of the arteries, a process that occurs slowly and 'silently' over decades. This prolonged course of disease provides a window of opportunity for diagnosis before symptoms occur. But, until recently, only advanced atherosclerotic disease could be observed.
Javier, Sanz, Zahi A, Fayad
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Update of HDL in atherosclerotic cardiovascular disease
Clínica e Investigación en Arteriosclerosis, 2023Epidemiologic evidence supported an inverse association between HDL (high-density lipoprotein) cholesterol (HDL-C) levels and atherosclerotic cardiovascular disease (ASCVD), identifying HDL-C as a major cardiovascular risk factor and postulating diverse HDL vascular- and cardioprotective functions beyond their ability to drive reverse cholesterol ...
Leonie, Schoch +6 more
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The Role of Colchicine in Atherosclerotic Cardiovascular Disease
Heart, Lung and Circulation, 2021Colchicine, an inexpensive immunomodulatory drug used traditionally to treat gout and familial Mediterranean fever, is rapidly accumulating basic and clinical evidence for a therapeutic role in atherosclerotic cardiovascular disease. Its athero-protective properties are thought to be mainly related to its effect on tubulin polymerisation, enabling a ...
Rahul Kurup +4 more
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Colchicine in atherosclerotic cardiovascular disease
HeartInflammation has a direct role in the development of atherosclerotic vascular disease, and oral colchicine displays broad anti-inflammatory properties. Several large, randomised controlled trials (RCTs) have evaluated colchicine’s impact on cardiovascular outcomes.
Bradley Tucker +3 more
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Lipid Peroxidation in Atherosclerotic Cardiovascular Diseases
Antioxidants & Redox Signaling, 2020Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries with lower economic development, and they constitute an ever-growing global burden that has a considerable socioeconomic impact on ...
Gianazza E. +6 more
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Autoimmune diseases and atherosclerotic cardiovascular disease
Nature Reviews CardiologyAutoimmune diseases are associated with a dramatically increased risk of atherosclerotic cardiovascular disease and its clinical manifestations. The increased risk is consistent with the notion that atherogenesis is modulated by both protective and disease-promoting immune mechanisms.
Florentina Porsch, Christoph J. Binder
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Ascorbic Acid and Atherosclerotic Cardiovascular Disease
1996In this chapter, we have briefly reviewed the current scientific knowledge of the role of vitamin C in the prevention of atherosclerosis and its associated clinical manifestations. There is good evidence from animal studies that vitamin C can slow the progression of experimental atherosclerosis.
S M, Lynch, J M, Gaziano, B, Frei
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PCSK9 Inhibition in Atherosclerotic Cardiovascular Disease
Current Pharmaceutical Design, 2023Abstract: Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) represent a novel class of hypolipidemic drugs, providing an additional therapeutic option over conventional hypolipidemic treatments. Given the constantly lowering recommended LDL-C goals, low goal achievement rate and low compliance with treatment, new hypolipidemic drug ...
Dimitrios, Delialis +8 more
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Sleep calibrates atherosclerotic cardiovascular disease
Nature Cardiovascular Research, 2022Sleep modulates cardiovascular health, and recent studies have begun to uncover underlying mechanistic links. An integrated translational approach that combines animal models and human trials will enrich scientific discovery, improve therapy, and help to alleviate the global burden of insufficient sleep and cardiovascular disease.
Oren Cohen +2 more
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