Results 211 to 220 of about 154,772 (354)
Long non-coding RNA lncAPAT promotes atherosclerotic plaque instability by targeting ribosomal protein L22. [PDF]
Li R +8 more
europepmc +1 more source
ABSTRACT This study investigated the effects of histone lactylation on ferroptosis in hypoxia‐induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2‐Deoxy‐D‐glucose (2‐DG, a glucose analogue), ferrostatin‐1 (Fer‐1, a selective ferroptosis inhibitor), lactate (LA), sh‐β‐catenin (shRNA of β‐catenin), or SKL2001 (an agonist ...
Xin‐Hua Zhu +6 more
wiley +1 more source
ABSTRACT Type 2 diabetes mellitus (T2DM) is associated with an increased risk of osteoporosis and fractures, and denosumab, a non‐kidney‐excreted antiresorptive medication, represents a viable alternative to bisphosphonates for osteoporosis treatment in patients with T2DM. This study aimed to investigate the association among denosumab adherence, renal
Yu‐Chuan Chang +7 more
wiley +1 more source
Dysregulated cellular metabolism drives atherosclerotic plaque progression: a multi-cellular perspective. [PDF]
Wang YH +5 more
europepmc +1 more source
ABSTRACT Acute coronary syndrome (ACS) is a clinical syndrome involving myocardial ischemia. This study aimed to elucidate the mechanism of TET3 in ACS‐induced CMEC damage, thereby identifying a new target for ACS treatment. The expression of TET3 in ACS patients and healthy subjects was analyzed.
Jun‐Cheng Liu +5 more
wiley +1 more source
Association between carotid atherosclerotic plaque characteristics and white matter hyperintensity in cerebral small vessel disease. [PDF]
Feng Q, Wang T, Zhu L.
europepmc +1 more source
ABSTRACT Radiotherapy effectively eradicates tumor cells but can also trigger pyroptotic damage in vascular endothelial cells. This study investigates the role of interferon regulatory factor 1 (IRF1) in radiation‐induced endothelial injury, aiming to provide mechanistic insights for optimizing radiotherapy.
Chen Li +4 more
wiley +1 more source
Carotid atherosclerotic plaques standardised uptake values: software challenges and reproducibility [PDF]
Nicola Giannotti +4 more
openalex +1 more source

