Relationship Between Perivascular Fat Inflammation and Coronary Atherosclerotic Plaque Composition. [PDF]
Engel LC +8 more
europepmc +1 more source
Current research reports that micro‐nanoplastics may increase the burden of cardiovascular disease with significant human and economic consequences. The detection of plastic particles in biological matrices is challenging and rigorous research is required to investigate the clinical and broader public health implications of microplastics.
Adrian Goldsworthy +4 more
wiley +1 more source
Spectral computed tomography characterization of coronary atherosclerotic plaque: principles, imaging biomarkers, and clinical significance. [PDF]
Liu Y, Peng Y, Wu H, Li Y.
europepmc +1 more source
Among 170,250 UK Biobank women (2006–2024), ever HRT use was associated with higher incident ASCVD risk (adjusted HR 1.13, 95% CI 1.08–1.18), largely driven by ischemic stroke. Associations were stronger in women ≤45 years and during perimenopause. Mediation via sex hormones, inflammatory markers, or lipids was minimal (<2%).
Mengchun Wang +6 more
wiley +1 more source
Multi-omics integration identifies ARID1B linking cuproptosis-immune crosstalk with atherosclerotic plaque progression. [PDF]
Hu X, Wei K, Pang P, Chang W, Huang L.
europepmc +1 more source
This study demonstrates that women with prior preeclampsia had significantly higher concentrations of PlGF when CT‐assessed coronary atherosclerosis was present years following the index pregnancy, whereas no difference was found for concentrations of sFlt‐1.
Signe Højstrup Bessing +11 more
wiley +1 more source
Nanotechnology for atherosclerotic plaque stabilisation: bridging innovation and clinical practice. [PDF]
Ren Y, Zhou Y, Xiang B, Li Q, Zhou X.
europepmc +1 more source
Neuropathology of a patient with Parkinson's disease and biallelic expansion in RFC1
This is the first report of neuropathology in biallelic RFC1 expansion‐associated Parkinson’s disease (PD). It shows a synucleinopathy of intraneuronal Lewy bodies consistent with the clinical PD diagnosis while neuropathological CANVAS (Cerebellar Ataxia with Neuropathy and bilateral Vestibular Areflexia) features were absent.
Jussi Sipilä +3 more
wiley +1 more source
Predicting Acute Myocardial Infarction in the Absence of Detectable Atherosclerotic Plaque With Perivascular Coronary Inflammation. [PDF]
Hinchman DA +3 more
europepmc +1 more source
Non‐canonical PKG1 regulation in cardiovascular health and disease
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source

