Results 201 to 210 of about 283,363 (298)

Relationship Between Perivascular Fat Inflammation and Coronary Atherosclerotic Plaque Composition. [PDF]

open access: yesJ Clin Med
Engel LC   +8 more
europepmc   +1 more source

Micro‐Nanoplastics Significantly Increase Adverse Events and Economic Burden Associated With Carotid Endarterectomy: A Health Economic Modelling Evaluation

open access: yesANZ Journal of Surgery, EarlyView.
Current research reports that micro‐nanoplastics may increase the burden of cardiovascular disease with significant human and economic consequences. The detection of plastic particles in biological matrices is challenging and rigorous research is required to investigate the clinical and broader public health implications of microplastics.
Adrian Goldsworthy   +4 more
wiley   +1 more source

Elevated cardiovascular risk associated with hormone replacement therapy: A comprehensive analysis of reproductive factors and atherosclerotic cardiovascular disease outcomes in the UK Biobank cohort

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Among 170,250 UK Biobank women (2006–2024), ever HRT use was associated with higher incident ASCVD risk (adjusted HR 1.13, 95% CI 1.08–1.18), largely driven by ischemic stroke. Associations were stronger in women ≤45 years and during perimenopause. Mediation via sex hormones, inflammatory markers, or lipids was minimal (<2%).
Mengchun Wang   +6 more
wiley   +1 more source

Angiogenic biomarker concentrations and their relation to coronary atherosclerosis in women with a history of preeclampsia: Findings from the CPH‐PRECIOUS study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
This study demonstrates that women with prior preeclampsia had significantly higher concentrations of PlGF when CT‐assessed coronary atherosclerosis was present years following the index pregnancy, whereas no difference was found for concentrations of sFlt‐1.
Signe Højstrup Bessing   +11 more
wiley   +1 more source

Neuropathology of a patient with Parkinson's disease and biallelic expansion in RFC1

open access: yesBrain Pathology, EarlyView.
This is the first report of neuropathology in biallelic RFC1 expansion‐associated Parkinson’s disease (PD). It shows a synucleinopathy of intraneuronal Lewy bodies consistent with the clinical PD diagnosis while neuropathological CANVAS (Cerebellar Ataxia with Neuropathy and bilateral Vestibular Areflexia) features were absent.
Jussi Sipilä   +3 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

open access: yesBritish Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

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