The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability
Mediators of Inflammation, 2020 Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability.
Tiewei Li +5 more
doaj +2 more sources
Localization of lipopolysaccharide from Escherichia Coli into human atherosclerotic plaque [PDF]
Scientific Reports, 2018 Experimental studies showed that gut-derived lipopolysaccharide (LPS) is pro-atherogenic, however, its relationship with human atherosclerosis is still to be defined.
Cammisotto, Vittoria +11 more
core +3 more sources
Regulation of atherosclerotic plaque inflammation [PDF]
Journal of Internal Medicine, 2015 AbstractThe immune reactions that regulate atherosclerotic plaque inflammation involve chemokines, lipid mediators and costimulatory molecules. Chemokines are a family of chemotactic cytokines that mediate immune cell recruitment and control cell homeostasis and activation of different immune cell types and subsets.
Back, M., Weber, C., Lutgens, E.
openaire +3 more sources
Chronic miR‐29 antagonism promotes favorable plaque remodeling in atherosclerotic mice
EMBO Molecular Medicine, 2016 Abnormal remodeling of atherosclerotic plaques can lead to rupture, acute myocardial infarction, and death. Enhancement of plaque extracellular matrix (ECM) may improve plaque morphology and stabilize lesions.
Victoria Ulrich +18 more
doaj +2 more sources
Effects of lipid-lowering therapy on coronary atherosclerotic plaque evaluated by intravascular imaging [PDF]
Jichu yixue yu linchuang, 2022 The progression of atherosclerotic plaque is one of the most important causes of cardiovascular events in patients with atherosclerotic cardiovascular diseases (ASCVD).
ZHANG Shuang, LI Zhi-fan, QIAN Jie, WU Na-qiong
doaj +1 more source
Inflammation during the life cycle of the atherosclerotic plaque.
Cardiovascular Research, 2021 Inflammation orchestrates each stage of the life cycle of atherosclerotic plaques. Indeed, inflammatory mediators likely link many traditional and emerging risk factors with atherogenesis.
P. Libby
semanticscholar +1 more source
Association of Lipoprotein(a) With Atherosclerotic Plaque Progression
Journal of the American College of Cardiology, 2022 Background Lipoprotein(a) [Lp(a)] is associated with increased risk of myocardial infarction, although the mechanism for this observation remains uncertain.
Y. Kaiser +16 more
semanticscholar +1 more source
Advances of nanoparticle-mediated diagnostic and theranostic strategies for atherosclerosis
Frontiers in Bioengineering and Biotechnology, 2023 Atherosclerotic plaque remains the primary cause of morbidity and mortality worldwide. Accurate assessment of the degree of atherosclerotic plaque is critical for predicting the risk of atherosclerotic plaque and monitoring the results after intervention.
Lin Lin +19 more
doaj +1 more source
Coronary Atherosclerotic Plaque Regression: JACC State-of-the-Art Review.
Journal of the American College of Cardiology, 2022 Over the last 3 decades there have been substantial improvements in treatments aimed at reducing cardiovascular (CV) events. As these treatments have been developed, there have been parallel improvements in coronary imaging modalities that can assess ...
Luke P. Dawson +4 more
semanticscholar +1 more source
Analysis of MicroRNAs Associated With Carotid Atherosclerotic Plaque Rupture With Thrombosis
Frontiers in Genetics, 2021 Atherosclerosis is a progressive vascular wall inflammatory disease, and the rupture of atherosclerotic vulnerable plaques is the leading cause of morbidity and mortality worldwide.
Peng Nie +4 more
doaj +1 more source