Results 11 to 20 of about 283,312 (250)

Carotid plaque stress analysis by fluid structure interaction based on in-vivo MRI: Implications to plaque vulnerability assessment [PDF]

, 2010
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University, 2010.Stroke is one of the leading causes of death in the world, resulting mostly from the sudden rupture of atherosclerotic plaques.
Gao, Hao
core   +7 more sources

A Hybrid Hierarchical Framework for Quantifying Mechanical Markers in Atherosclerotic Disease Progression: A New Approach for Diagnosis and Risk Assessment. [PDF]

Adv Sci (Weinh)
The mechanobiological basis of atherosclerotic progression and its contribution to spatial and temporal heterogeneity remain incompletely understood. Spatially resolved AFM measurements revealed that plaque formation and distinct regions (cap fibrosis, intimal fibrosis, and lipid‐rich core) exhibit heterogeneous elastic modulus and viscoelastic ...
Zhou Y, Chang Z, Wu X, Wang S, Zhang Y, Zhang H, Xu H, Peng R, Wang Z, Xu H, Liu Y, Xu G, Zhang N, Yang H.   +13 more
europepmc   +2 more sources

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72^hi Macrophages and Blocking CXCL12-CXCR4 Axis to Inhibit Endothelial Pyroptosis. [PDF]

Adv Sci (Weinh)
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
He X, Li S, Chen J, Lin L, Li X, Zhang X, Zhang Y, Chen X, Guo J, Yang Z, Lu L, Ni S.   +11 more
europepmc   +2 more sources

Serial Molecular-Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice. [PDF]

Adv Sci (Weinh)
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Li J, Tan JTM, Xiang L, Liu J, Hoogendoorn A, Nankivell VA, Sandeman L, Le R, Chen R, McLaughlin RA, Psaltis PJ, Verjans JW, Bursill CA.   +12 more
europepmc   +2 more sources

Carotid plaque vulnerability assessment by microscopic morphology analysis, ultrasound and 3D model reconstruction [PDF]

, 2012
This thesis was submitted for the degree of Docter of Philosophy and awarded by Brunel University.Research suggests that plaque morphology plays a crucial role in determining plaque vulnerability.
Choudhury, Ahsan
core   +7 more sources

Recent Trends in Artificial Intelligence-Assisted Coronary Atherosclerotic Plaque Characterization [PDF]

, 2021
Coronary artery disease is a major cause of morbidity and mortality worldwide. Its underlying histopathology is the atherosclerotic plaque, which comprises lipid, fibrous and—when chronic—calcium components.
Ashwal, A J, Nayak, Sneha, Barua, Prabal Datta, Raghavendra, U., Sneha Nayak, Jyothi Samanth, Anjan Gudigar, U Raghavendra, U. Rajendra Acharya, Ciaccio, Edward J., Edward J. Ciaccio, Hasan, Md Nazmul, Samanth, Jyothi, Prabal Datta Barua, Acharya, U. Rajendra, Md Nazmul Hasan, Ru-San Tan, Ashwal A J, Gudigar, Anjan, Tan, Ru-San   +19 more
core   +1 more source

The Role of Matrix Metalloproteinase-9 in Atherosclerotic Plaque Instability

Mediators of Inflammation, 2020
Matrix metalloproteinase-9 (MMP-9) belongs to the MMP family and has been widely investigated. Excessive MMP-9 expression can enhance extracellular matrix degradation and promote plaque instability.
Tiewei Li, Xiaojuan Li, Yichuan Feng, Geng Dong, Yuewu Wang, Junmei Yang   +5 more
doaj   +1 more source

Intermedin1-53 attenuates atherosclerotic plaque vulnerability by inhibiting CHOP-mediated apoptosis and inflammasome in macrophages

Cell Death and Disease, 2021
Atherosclerotic plaque vulnerability and rupture increase the risk of acute coronary syndromes. Advanced lesion macrophage apoptosis plays important role in the rupture of atherosclerotic plaque, and endoplasmic reticulum stress (ERS) has been proved to ...
Jin-Ling Ren, Yao Chen, Lin-Shuang Zhang, Ya-Rong Zhang, Shi-Meng Liu, Yan-Rong Yu, Mo-Zhi Jia, Chao-Shu Tang, Yong-Fen Qi, Wei-Wei Lu   +9 more
doaj   +1 more source

Increases of Corporal Temperature as a Risk Factor of Atherosclerotic Plaque Instability [PDF]

, 2008
This work explores for the first time the effects of temperature increments on the development of high shear stresses between plaque and arterial wall due to their different dilatational properties. Data from the literature report febrile reactions prior
Rojo Pérez, Francisco Javier, Elices, Margarita L., Gonzalez, Pablo, Ortega Pozzi, Aranzazu, Elices Calafat, Manuel, Torres Coronado, Monica, Guinea Tortuero, Gustavo V., Fantidis, Panayotis, Atienza Riera, José Miguel, Hayashi, Kozaburo   +9 more
core   +1 more source

Research Progress on the Risk Factors and Outcomes of Human Carotid Atherosclerotic Plaques

Chinese Medical Journal, 2017
Objective: Atherosclerosis is an inflammatory process that results in complex lesions or plaques that protrude into the arterial lumen. Carotid atherosclerotic plaque rupture, with distal atheromatous debris embolization, causes cerebrovascular events ...
Xiang-Dong Xiong, Wei-Dong Xiong, Shang-Shen Xiong, Gui-Hai Chen   +3 more
doaj   +1 more source