Results 11 to 20 of about 575,333 (346)

Atherosclerotic Carotid Plaque Composition and Incident Stroke and Coronary Events.

Journal of the American College of Cardiology, 2021
BACKGROUND Increasing evidence suggests that atherosclerotic plaque composition rather than plaque size is linked to ischemic cardiovascular events, yet largescale population-based data in asymptomatic individuals remain scarce.
D. Bos, B. Arshi, Quirijn J A van den Bouwhuijsen, M. Ikram, M. Selwaness, M. Vernooij, M. Kavousi, A. van der Lugt   +7 more
semanticscholar   +1 more source

The Effect of PCSK9 Inhibition on the Stabilization of Atherosclerotic Plaque Determined by Biochemical and Diagnostic Imaging Methods

Molecules, 2023
Atherosclerosis is a multifactorial, progressive, chronic inflammatory disease. Ultrasound and magnetic resonance imaging are the most accurate predictors of atherosclerotic plaque instability (MRI).
Marcin Basiak, Marcin Hachula, Michal Kosowski, Grzegorz Machnik, Mateusz Maliglowka, Maria Dziubinska-Basiak, Robert Krysiak, Boguslaw Okopien   +7 more
doaj   +1 more source

Potential circulating biomarkers of atherosclerotic plaque vulnerability in patients in the early recovery period of atherothrombotic stroke [PDF]

The Ukrainian Biochemical Journal, 2023
Despite the informative value of ultrasound examination of atherosclerotic vascular lesions, predicting­ the plaque vulnerabili­ty remains difficult. Circulating blood biomarkers could provide additional criteria that would allow better determination of ...
O. Ya. Mykhalojko, I. Ya. Mykhalojko
doaj   +1 more source

Association of Statin Treatment With Progression of Coronary Atherosclerotic Plaque Composition.

JAMA cardiology, 2021
Importance The density of atherosclerotic plaque forms the basis for categorizing calcified and noncalcified morphology of plaques. Objective To assess whether alterations in plaque across a range of density measurements provide a more detailed ...
A. V. van Rosendael, I. J. van den Hoogen, U. Gianni, Xiaoyue Ma, S. Tantawy, A. Bax, Yao Lu, D. Andreini, M. Al-Mallah, M. Budoff, Filippo Cademartiri, K. Chinnaiyan, J. Choi, E. Conte, H. Marques, P. de Araújo Gonçalves, I. Gottlieb, M. Hadamitzky, J. Leipsic, E. Maffei, G. Pontone, Sanghoon Shin, Yong‐Jin Kim, Byoung‐Kwon Lee, E. Chun, J. Sung, Sang-Eun Lee, R. Virmani, H. Samady, Y. Sato, P. Stone, D. Berman, J. Narula, R. Blankstein, J. Min, F. Lin, L. Shaw, Jeroen J. Bax, H. Chang   +38 more
semanticscholar   +1 more source

The Applications of Single-Cell RNA Sequencing in Atherosclerotic Disease

Frontiers in Cardiovascular Medicine, 2022
Atherosclerosis still is the primary cause of death worldwide. Our characterization of the atherosclerotic lesion is mainly rooted in definitions based on pathological descriptions.
Lotte Slenders, Daniëlle E. Tessels, Sander W. van der Laan, Gerard Pasterkamp, Michal Mokry, Michal Mokry   +5 more
doaj   +1 more source

Highly sensitive magnetic particle imaging of vulnerable atherosclerotic plaque with active myeloperoxidase-targeted nanoparticles

Theranostics, 2021
Inflammation is a pivotal driver of atherosclerotic plaque progression and rupture and is a target for identifying vulnerable plaques. However, challenges arise with the current in vivo imaging modalities for differentiating vulnerable atherosclerotic ...
Wei Tong, Hui Hui, W. Shang, Yingqian Zhang, F. Tian, Q. Ma, Xin Yang, Jie Tian, Yundai Chen   +8 more
semanticscholar   +1 more source

Plasma Testosterone Levels and Atherosclerotic Plaque Gene Expression in Men With Advanced Atherosclerosis

Frontiers in Cardiovascular Medicine, 2021
Aims: Low plasma testosterone levels have been shown to predict worse outcome in men with severe atherosclerotic disease. We hypothesized that a low plasma testosterone level affects disease risk through changes in gene expression in atherosclerotic ...
Floor Groepenhoff, Floor Groepenhoff, Ernest Diez Benavente, Arjan Boltjes, Nathalie Timmerman, Farahnaz Waissi, Robin J. G. Hartman, N. C. Onland-Moret, Gerard Pasterkamp, Hester Den Ruijter   +9 more
doaj   +1 more source

Macrophage death in atherosclerosis: potential role in calcification

Frontiers in Immunology, 2023
Cell death is an important aspect of atherosclerotic plaque development. Insufficient efferocytosis of death cells by phagocytic macrophages leads to the buildup of a necrotic core that impacts stability of the plaque.
Jaap G. Neels, Claire Gollentz, Giulia Chinetti   +2 more
doaj   +1 more source

Ginsenoside Rb1 Enhances Plaque Stability and Inhibits Adventitial Vasa Vasorum via the Modulation of miR-33 and PEDF

Frontiers in Cardiovascular Medicine, 2021
Background: Atherosclerosis is closely associated with proliferation of the adventitial vasa vasorum, leading to the atherosclerotic plaque progression and vulnerability.
Xiaoyan Yang, Xiaoyan Yang, Lei Wang, Zihao Zhang, Jiayi Hu, Xiaoling Liu, Hao Wen, Hao Wen, Minghao Liu, Minghao Liu, Xue Zhang, Xue Zhang, Hongyan Dai, Mei Ni, Rui Li, Rong Guo, Lei Zhang, Xiaorong Luan, Huili Lin, Mei Dong, Huixia Lu   +20 more
doaj   +1 more source

Percent atheroma volume: Optimal variable to report whole-heart atherosclerotic plaque burden with coronary CTA, the PARADIGM study. [PDF]

, 2020
BACKGROUND AND AIMS:Different methodologies to report whole-heart atherosclerotic plaque on coronary computed tomography angiography (CCTA) have been utilized.
Al Hussein, Omar, Al'Aref, Subhi J, Al-Mallah, Mouaz H, Andreini, Daniele, Bax, Jeroen J, Berman, Daniel S, Budoff, Matthew J, Cademartiri, Filippo, Chang, Hyuk-Jae, Chinnaiyan, Kavitha, Choi, Jung Hyun, Chun, Eun Ju, Conte, Edoardo, de Araújo Gonçalves, Pedro, Gianni, Umberto, Gottlieb, Ilan, Hadamitzky, Martin, Kim, Yong-Jin, Lee, Byoung Kwon, Lee, Sang-Eun, Leipsic, Jonathon A, Lin, Fay Y, Ma, Xiaoyue, Maffei, Erica, Marques, Hugo, Min, James K, Narula, Jagat, Peña, Jessica M, Pontone, Gianluca, Raff, Gilbert L, Samady, Habib, Shaw, Leslee J, Shin, Sanghoon, Stone, Peter H, Sung, Ji Min, van den Hoogen, Inge J, van Rosendael, Alexander R, Virmani, Renu   +37 more
core   +2 more sources