Results 31 to 40 of about 98,121 (309)

oxLDL downregulates the dendritic cell homing factors CCR7 and CCL21 [PDF]

, 2012
Dendritic cells (DCs) and oxLDL play an important role in the atherosclerotic process with DCs accumulating in the plaques during plaque progression.
Korbinian Lackermair, Kopp, Reinhard, Beiras-Fernandez, Andres, Kaczmarek, Ingo, Summo, Claudia, Andres Beiras-Fernandez, Weis, Michael, Robert David, Michael Weis, Marius Lambert, Thomas Nickel, Ingo Kaczmarek, Claudia Summo, Sicic, Zeljka, Georgios Meimarakis, Lackermair, Korbinian, Lambert, Marius, Nickel, Thomas, Susanne Pfeiler, Pfeiler, Susanne, Meimarakis, Georgios, Reinhard Kopp, Lackermair, Korbinian Johannes, Beiras Fernández, Andrés, Zeljka Sicic, David, Robert   +25 more
core   +1 more source

The biological effects of subacute inhalation of diesel exhaust following addition of cerium oxide nanoparticles in atherosclerosis-prone mice [PDF]

, 2012
Background: Ceriumoxide(CeO2) nano particles improve the burning efficiency of fuel,however,little is known about health impacts of altered emissions from the vehicles.Methods: Atherosclerosis-prone apolipoprotein Eknockout (ApoE/) mice were exposed by ...
Boere, A. John F., Cassee, Flemming R., Miller, Mark R., Mclean, Steven G., Campbell, Arezoo, Duffin, Rodger, Gosens, Ilse, Krystek, Petra   +7 more
core   +1 more source

Desipramine enhances the stability of atherosclerotic plaque in rabbits monitored with molecular imaging.

PLoS ONE, 2023
Acid sphingomyelinase (ASM) promotes atherogenesis and acute cardiovascular events. We previously demonstrated ASM inhibitor desipramine attenuated oxidized-LDL-induced macrophage apoptosis in vitro.
Min Zhao, Baiyang You, Xiaole Wang, Jin Huang, Ming Zhou, Ruizheng Shi, Guogang Zhang   +6 more
doaj   +2 more sources

Effect of calcification on the mechanical stability of plaque based on a three-dimensional carotid bifurcation model

BMC Cardiovascular Disorders, 2012
Background This study characterizes the distribution and components of plaque structure by presenting a three-dimensional blood-vessel modelling with the aim of determining mechanical properties due to the effect of lipid core and calcification within a ...
Wong Kelvin KL, Thavornpattanapong Pongpat, Cheung Sherman CP, Sun Zhonghua, Tu Jiyuan   +4 more
doaj   +1 more source

High-Resolution MRI of Intracranial Atherosclerotic Disease [PDF]

Neurointervention, 2014
Intracranial atherosclerotic disease (ICAD) causes up to 10% of all ischemic strokes, and the rate of recurrent vascular ischemic events is very high. Important predictors of vulnerability in atherosclerotic plaques include the degree of stenosis and the
Chang-Woo Ryu, Hyo-Sung Kwak, Geon-Ho Jahng, Han Na Lee   +3 more
doaj   +1 more source

Vulnerable Atherosclerotic Plaque [PDF]

Circulation, 2003
The recent proliferation of invasive and noninvasive techniques to locate vulnerable atherosclerotic plaques raises important questions. Will such techniques add useful prognostic information? If so, will the information prevent myocardial infarction, stroke, or death in at least some patients at risk? Will it lead to new research advances?
Ward, Casscells, Morteza, Naghavi, James T, Willerson   +2 more
openaire   +2 more sources

Increases of Corporal Temperature as a Risk Factor of Atherosclerotic Plaque Instability

, 2008
This work explores for the first time the effects of temperature increments on the development of high shear stresses between plaque and arterial wall due to their different dilatational properties. Data from the literature report febrile reactions prior
Rojo Pérez, Francisco Javier, Elices, Margarita L., Gonzalez, Pablo, Ortega Pozzi, Aranzazu, Elices Calafat, Manuel, Torres Coronado, Monica, Guinea Tortuero, Gustavo V., Fantidis, Panayotis, Atienza Riera, José Miguel, Hayashi, Kozaburo   +9 more
core   +1 more source

Comparison of cardiovascular biomarker expression in extracellular vesicles, plasma and carotid plaque for the prediction of MACE in CEA patients

Scientific Reports, 2023
Extracellular vesicles (EV) are a novel biomarker source for diagnosis and prognosis of cardiovascular disease. A protein comparison of plasma EVs in relation to blood plasma and atherosclerotic plaque has not been performed but would provide insight ...
Maarten C. Verwer, Joost Mekke, Nathalie Timmerman, Farahnaz Waissi, Arjan Boltjes, Gerard Pasterkamp, Gert J. de Borst, Dominique P. V. de Kleijn   +7 more
doaj   +1 more source

Myeloid cell-specific Irf5 deficiency stabilizes atherosclerotic plaques in Apoe–/– mice

Molecular Metabolism, 2021
Objective: Interferon regulatory factor (IRF) 5 is a transcription factor known for promoting M1 type macrophage polarization in vitro. Given the central role of inflammatory macrophages in promoting atherosclerotic plaque progression, we hypothesize ...
Julia Leipner, Tsai-Sang Dederichs, Alexander von Ehr, Simon Rauterberg, Carolin Ehlert, Julian Merz, Bianca Dufner, Natalie Hoppe, Katja Krebs, Timo Heidt, Constantin von zur Muehlen, Peter Stachon, Klaus Ley, Dennis Wolf, Andreas Zirlik, Christoph Bode, Ingo Hilgendorf, Carmen Härdtner   +17 more
doaj   +1 more source

A Novel Plaque Enriched Long Noncoding RNA in Atherosclerotic Macrophage Regulation (PELATON) [PDF]

, 2019
Objective:Long noncoding RNAs (lncRNAs) are an emergent class of molecules with diverse functional roles, widely expressed in human physiology and disease.
Andrew H. Baker, Connor, Katie, Newby, David E., Margaux A.C. Fontaine, Hung, John, Ballantyne, Margaret, Erik A.L. Biessen, Fontaine, Margaux A. C., Katie L. Connor, Amira D. Mahmoud, Biessen, Erik, Mahmoud, Amira D., Scanlon, Jessica, Jessica P. Scanlon, Biessen, Erik A. L., Rodor, Julie, Sluimer, Judith C.; id_orcid, Bhushan, Raghu, Connor, Katie L., Judith C. Sluimer, Lieve Temmerman, Scanlon, Jessica P., Fontaine, Margaux, Jakub Kaczynski, Julie Rodor, Kaczynski, Jakub, Sluimer, Judith, David E. Newby, Biessen, Erik A. L.; id_orcid, Margaret Ballantyne, Temmerman, Lieve, Raghu Bhushan, Sluimer, Judith C., Baker, Andrew H., John Hung, Mahmoud, Amira   +35 more
core   +1 more source