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Atherosclerotic plaque near the carotid sinus is a key risk factor for ischemic stroke. Although disturbed hemodynamic environments around atherosclerotic plaque had been investigated in many studies, the effect of their symmetrical features, especially ...
Xianghui Gong +5 more
doaj +1 more source
Atherosclerotic carotid plaque segmentation [PDF]
Atherosclerosis is the major cause of heart attack and stroke in the western world. In this paper we present a computerized method for segmenting the athrerosclerotic carotid plaque from ultrasound images. The method uses the blood flow image first to detect the initial contour of the plaque, and then despeckle filtering and snakes to deform the ...
Loizou, Christos P. +4 more
openaire +3 more sources
Npp1 promotes atherosclerosis in ApoE knockout mice. [PDF]
Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (NPP1) generates inorganic pyrophosphate (PP(i)), a physiologic inhibitor of hydroxyapatite deposition.
Nitschke, Yvonne +3 more
core +1 more source
Percutaneous Coronary Intervention for Vulnerable Coronary Atherosclerotic Plaque.
BACKGROUND Acute coronary syndromes most commonly arise from thrombosis of lipid-rich coronary atheromas that have large plaque burden despite angiographically appearing mild.
G. Stone +18 more
semanticscholar +1 more source
Imaging atherosclerotic plaque inflammation [PDF]
Inflammation within atherosclerotic plaques is one of the main drivers of atherosclerotic plaque rupture, which frequently leads to clinical events such as myocardial infarction and stroke. Current gold standard techniques such as X-ray angiography and ultrasound can rapidly report on luminal encroachment but give no readout on inflammatory state of ...
James H F, Rudd, Zahi A, Fayad
openaire +2 more sources
Calcification in Atherosclerotic Plaque Vulnerability: Friend or Foe?
Calcification is a clinical marker of atherosclerosis. This review focuses on recent findings on the association between calcification and plaque vulnerability.
Xuan-YAN Shi +6 more
semanticscholar +1 more source
Vulnerable Atherosclerotic Plaque [PDF]
The recent proliferation of invasive and noninvasive techniques to locate vulnerable atherosclerotic plaques raises important questions. Will such techniques add useful prognostic information? If so, will the information prevent myocardial infarction, stroke, or death in at least some patients at risk? Will it lead to new research advances?
Ward, Casscells +2 more
openaire +2 more sources
Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis [PDF]
Macrophages specialize in removing lipids and debris present in the atherosclerotic plaque. However, plaque progression renders macrophages unable to degrade exogenous atherogenic material and endogenous cargo including dysfunctional proteins and ...
Ali, Sahl +19 more
core +2 more sources
Atherosclerotic carotid plaque composition: a 3T and 7T MRI-histology correlation study [PDF]
Background and Purpose Carotid artery atherosclerotic plaque composition may influence plaque stability and risk of thromboembolic events, and non-invasive plaque imaging may therefore permit risk stratification for clinical management.
Condon, B. +7 more
core +1 more source
Invasive angiography has been widely accepted as the gold standard to diagnose cardiovascular pathologies. Despite its superior resolution of demonstrating atherosclerotic plaque in terms of degree of lumen stenosis, the morphological assessment for the ...
Zhonghua Sun
doaj +1 more source

