Results 181 to 190 of about 283,363 (298)

Early ApoA-I Treatment Prevents Postsurgical Atherosclerotic Plaque Destabilization. [PDF]

Circ Res
Boucher DM, Lorant V, Barney RP, Bhunu B, Gordon SM, Ouimet M.   +5 more
europepmc   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

Phytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia, Despoina Pantazi   +1 more
wiley   +1 more source

Exercise Improves Atherosclerotic Plaque Stability Through Macrophage Autophagy and the FGF21 Signaling Pathway. [PDF]

Int J Mol Sci
Li Q, Mao W, Lu Y, Lu T, Xu X, Pan Y, Lee SK, Wang L, Li T, Zhou J, Li W, Korivi M.   +11 more
europepmc   +1 more source

Protosappanin A Alleviates Atherosclerosis by Regulating the MDM2/GPX4 Axis‐Mediated Endothelial Ferroptosis

Phytotherapy Research, EarlyView.
PTA alleviates atherosclerosis by regulating the MDM2/GPX4 axis‐mediated endothelial ferroptosis. ABSTRACT Endothelial ferroptosis is a crucial pathogenic driver of atherosclerosis (AS) progression. Protosappanin A (PTA), a bioactive compound from Caesalpinia sappan L., protects cardiovascular vessels by regulating ferroptosis.
Jiamei Fu, Lin Zhu, Wenwei Yang, Mengnan Li, Zhixin Wu, Shude Sun, Yabin Zhou   +6 more
wiley   +1 more source

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

Gut microbiota-associated leucine elevation promotes cold-induced atherosclerotic plaque formation and instability. [PDF]

J Transl Med
Yan S, Fang N, Zhang Y, Zhang N, Liang Q, Duan Y, Li L, Li Y, Gong Y.   +8 more
europepmc   +1 more source

pKa engineering of a near‐infrared fluorescent probe for sensitive imaging of oxidative stress in atherosclerotic plaques

Smart Molecules, EarlyView.
A pKa‐engineered near‐infrared fluorescent probe (DCM‐2F‐B) enables sensitive imaging of oxidative stress in atherosclerotic plaques. Difluoro substitution lowers the phenolic hydroxyl pKa from 9.1 to 6.0, achieving near‐complete ionization at physiological pH.
Qianqian Yu, Jiahui Liang, Tijian Zhou, Qiaomeng Chen, Xuechun Yan, Zhikang Zheng, Huyou Wang, Jihong Liu, Yi Dong, Wei‐Hong Zhu, Qi Wang   +10 more
wiley   +1 more source

A Mathematical Model for Smooth Muscle Cell Phenotype Switching In Atherosclerotic Plaque. [PDF]

Bull Math Biol
Ndenda JP, Watson MG, Misra A, Myerscough MR.   +3 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

CD8⁺ effector memory and regulatory T cell dynamics predict subclinical atherosclerotic plaque formation in healthy aging. [PDF]

Immun Ageing
Weyh C, Größer V, Minuzzi LG, Frech T, Gebhardt K, Nolte S, Dombrowski TR, Böttrich T, Hoffmann MA, Sommer N, Ringseis R, Eder K, Sossalla S, Bauer P, Krüger K.   +14 more
europepmc   +1 more source