Results 301 to 310 of about 510,672 (398)

Atherosclerotic Plaques Composed of a Large Core of Foam Cells Covered with Thin Fibrous Caps in Twice-injured Carotid Arterial Specimens Obtained From High Cholesterol Diet-Fed Rabbits

, 2000
Takashi Yano, Hiroyuki Kawano, Hidenori Mochizuki, Osamu Doi, Takao Nakamura, Yasushi Saitō   +5 more
openalex   +1 more source

Cardiac troponin at the point of care in acute and chronic coronary syndromes

Diabetes, Obesity and Metabolism, EarlyView.
Abstract High‐sensitivity cardiac troponin (hs‐cTn) assays are integral to the assessment of patients with acute chest pain where prompt and accurate diagnosis of myocardial infarction enables timely delivery of potentially life‐saving treatment. In the Emergency Department, implementation of central laboratory hs‐cTn assays has reduced length of stay ...
Michael McDermott, Yong Yong Tew, Jamie G. Cooper, Deepak Harry, Nicholas L. Mills   +4 more
wiley   +1 more source

Dysregulated cholesterol uptake and efflux of bone marrow-derived α-SMA⁺ macrophages contribute to atherosclerotic plaque formation. [PDF]

Cell Mol Life Sci
Li M, Wu L, Wen Y, Wang A, Zhou X, Ren L, Lu Q, Li F, Zhu L, Tang C.   +9 more
europepmc   +1 more source

From liver to limb: Exploring the association between fatty liver disease and peripheral artery disease—A systematic review

European Journal of Clinical Investigation, EarlyView.
Abstract Introduction Fatty liver disease, encompassing nonalcoholic fatty liver disease (NAFLD), metabolic dysfunction‐associated fatty liver disease (MAFLD), and the recently redefined metabolic dysfunction‐associated steatotic liver disease (MASLD), is a growing global health concern with significant cardiovascular implications.
Vera Ciornolutchii, Abdulrahman Ismaiel, Jennifer Bogdan, Stefan‐Lucian Popa, Teodora Surdea‐Blaga, Dan L. Dumitrascu   +5 more
wiley   +1 more source

Association of systolic blood pressure time in target range with carotid atherosclerotic plaque and carotid intima-media thickness in hypertensive patients. [PDF]

Sci Rep
Li W, Liu Z, Zhao J, Wu S, Chen S, Huang W, Liu X, Gao Y.   +7 more
europepmc   +1 more source

PCSK9 and coronary atherosclerosis progression beyond LDL‐cholesterol in coronary artery disease patients

European Journal of Clinical Investigation, EarlyView.
In a population of patients with stable CAD, circulating levels of PCSK9 are independently associated with the progression of adverse coronary plaque phenotypes, as assessed by serial coronary computed tomography angiography. At RNA‐seq analysis of whole blood, PCSK9 was linked to the expression of genes involved in the innate‐immune response.
Rosetta Ragusa, Silvia Rocchiccioli, Serena Del Turco, Antonio Morlando, Giuseppina Basta, Arthur Scholte, Danilo Neglia, Chiara Caselli   +7 more
wiley   +1 more source

The metabolism of big endothelin-1 axis and lipids affects carotid atherosclerotic plaque stability - the possible opposite effects of treatment with statins and aspirin. [PDF]

Pharmacol Rep
Płoński A, Krupa A, Pawlak D, Sokołowska K, Sieklucka B, Gabriel M, Płoński AF, Głowiński J, Pawlak K.   +8 more
europepmc   +1 more source

Haemophilia Prophylaxis in the Age of Innovation: Exploring Opportunities for Personalized Treatment

Haemophilia, EarlyView.
ABSTRACT Introduction Recent advancements in haemophilia treatment have introduced a range of innovative therapies, including activated FVIII mimetics, ultra‐extended half‐life recombinant FVIII, rebalancing agents and gene therapy. These developments have transformed treatment options and expanded prophylaxis strategies.
Yesim Dargaud, Fabienne Volot, Stephanie Desage, Claire Pouplard, Valerie Chamouard, Anne Lienhart   +5 more
wiley   +1 more source

Endothelial KDM5B Regulated by Piezo1 Contributes to Disturbed Flow Induced Atherosclerotic Plaque Formation. [PDF]

J Cell Mol Med
Wu L, Jiang S, Zhou X, Li W, Ke J, Liu Z, Ren L, Lu Q, Li F, Tang C, Zhu L.   +10 more
europepmc   +1 more source

The Landscape of SPP1+ Macrophages Across Tissues and Diseases: A Comprehensive Review

Immunology, EarlyView.
SPP1+ macrophages represent a conserved, disease‐associated population present across cancerous and non‐cancerous conditions, involved in immunosuppression, fibrosis, lipid metabolism, phagocytosis, and other cellular processes. This review highlights their shared molecular programmes across tissues, their interactions with stromal and immune cells ...
Alessandro Palma
wiley   +1 more source