Results 341 to 350 of about 510,672 (398)
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Imaging of atherosclerotic plaque

The International Journal of Cardiovascular Imaging, 2004
The behavior and composition of coronary atherosclerotic plaques are ultimately responsible for the threat of acute ischemic events in patients with coronary artery disease. Different imaging modalities have been developed over the last several years in order to better characterize the atherosclerotic plaque and attempt to predict those in peril of ...
Dominick J. Angiolillo   +2 more
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Atherosclerotic plaque development

The International Journal of Biochemistry & Cell Biology, 2009
Atherosclerosis is now recognized as an inflammatory/immunomodulatory reaction to the presence of oxidized low-density lipoproteins within the arterial wall, often times in the setting of such risk factors as family history, hypercholesterolemia, high blood pressure, diabetes mellitus and smoking.
Quang T. Bui   +2 more
openaire   +3 more sources

Devouring atherosclerotic plaques

Nature Nanotechnology, 2020
Targeting of local macrophages by functionalized carbon nanotubes enables efferocytosis and clearance of atherosclerotic plaques.
openaire   +3 more sources

The Atherosclerotic Plaque

2009
Even though coronary, cerebral, and peripheral arterial disease represents the most common features of atherosclerosis, it progresses in the absence of any symptoms for most of its developmental course. Generally, the severity of a coronary stenosis is of poor predictive value for cardiac events such as sudden death, myocardial infarction, or unstable ...
Massimo Fioranelli   +2 more
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Taking AIM2 at atherosclerotic plaques

Nature Reviews Drug Discovery, 2021
Clonal haematopoiesis — an expansion of blood cell clones due to advantageous somatic mutations — is linked to myocardial infarction. A new study shows that activation of the AIM2 inflammasome in clonally expanded macrophages exacerbates atherosclerosis by driving both proliferation and pyroptosis.
openaire   +4 more sources

Development of atherosclerotic plaques

Acta Medica Scandinavica, 1985
ABSTRACT. Atherosclerosis is a multifactorial disease. A unified model for the lesion development reveals many connections between the response‐to‐injury hypothesis and the lipid hypothesis. Various cellular uptake mechanisms for native and modified lipoproteins are discussed with respect to foam cell formation and lesion development.
openaire   +3 more sources

Apoptosis in human atherosclerotic plaques

Apoptosis, 1999
Intimal cell death has been a recognized feature of advanced atherosclerotic disease. With the advent of DNA in situ end labelling and/or ultrastructural techniques, recent findings suggest that cells of an atheroma undergo programmed cell death or apoptosis. The pathophysiologic relevance of apoptosis in atherosclerotic disease is debatable. Apoptotic
Renu Virmani   +3 more
openaire   +3 more sources

Agents that stabilise atherosclerotic plaque

Expert Opinion on Investigational Drugs, 2003
The concept of plaque stabilisation was developed to explain how medications could decrease adverse coronary events without a substantial reduction in the regression of atherosclerosis. With this concept, a comprehensive view of atherosclerosis is now appreciated.
Jun R Chiong, Alan B Miller
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Rapid inhibition of atherosclerotic plaque progression by sonodynamic therapy

Cardiovascular Research, 2018
Aims Currently, efficient regimens to reverse atherosclerotic plaques are not available in the clinic. Herein, we present sonodynamic therapy (SDT) as a novel methodology to rapidly inhibit progression of atherosclerotic plaques. Methods and results In
Xin Sun   +29 more
semanticscholar   +1 more source

Atherosclerotic plaque

2015
Over the past decade, significant strides have been made in advanced non-invasive cardiac imaging. Technological advances in both hardware and software applications have made direct visualization of atherosclerotic plaque a reality. These advances have come at a crucial time, and help to fill a gap in contemporary diagnostic modalities, which have ...
P. Singh, A. Tawakol
openaire   +2 more sources

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