Results 121 to 130 of about 503,928 (378)
oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21
Mediators of Inflammation, 2012 Introduction. Dendritic cells (DCs) and oxLDL play an important role in the atherosclerotic process with DCs accumulating in the plaques during plaque progression.
Thomas Nickel +11 more
doaj +1 more source
Ursolic acid enhances macrophage autophagy and attenuates atherogenesis [PDF]
, 2016 Macrophage autophagy has been shown to be protective against atherosclerosis. We previously discovered that ursolic acid (UA) promoted cancer cell autophagy.
Fan, Daping +7 more
core +2 more sources
Nano letters (Print), 2014 The underlying cause of major cardiovascular events, such as myocardial infarctions and strokes, is atherosclerosis. For accurate diagnosis of this inflammatory disease, molecular imaging is required. Toward this goal, we sought to develop a nanoparticle-
M. Bruckman +6 more
semanticscholar +1 more source
Advanced Science, EarlyView.Sclerostin loop2‐ApoER2 interaction in macrophages is required by sclerostin to suppress NF‐κB nuclear translocation and phosphorylation, to promote macrophage conversion into anti‐inflammatory subtypes in atherosclerotic aortas, as well as to prevent atherosclerosis and aortic aneurysm development in ApoE−/− mice. Abstract Therapeutic antibody against
Luyao Wang +27 more
wiley +1 more source
Follicle-stimulating hormone receptor expression in advanced atherosclerotic plaques
Scientific ReportsExperimental evidence indicates that follicle-stimulating hormone (FSH), an essential hormone for reproduction, can act directly on endothelial cells inducing atherosclerosis activation and development.
Nicolae Ghinea +4 more
doaj +1 more source
CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target
Advanced Science, EarlyView.This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang +2 more
wiley +1 more source
The roles of endoglin gene in cerebrovascular diseases. [PDF]
, 2017 Endoglin (ENG, also known as CD105) is a transforming growth factor β (TGFβ) associated receptor and is required for both vasculogenesis and angiogenesis.
Ma, Li, Su, Hua, Zhang, Rui, Zhu, Wan
core +2 more sources
Advanced Science, EarlyView.This study demonstrates multifactorial lifestyle impacts on the pathogenesis and progression of cardiovascular diseases by a nanofluorescence sensor array for detecting four redox species and protein phosphorylation levels. Through cross‐scale fluorescence imaging of rats with different diets, we revealed that compared with single dietary interventions,
Jin Li +9 more
wiley +1 more source
Наука и инновации в медицине, 2017 Aim - to study the correlation between the thickness of the fibrous cap and collagen in the coronary and carotid plaques in patients with myocardial infarction. Materials and methods.
LN N Slatova +4 more
doaj +1 more source
Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]
, 2018 Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura +8 more
core +2 more sources