Results 321 to 330 of about 118,937 (337)

Evaluation of Coronary Atherosclerotic Plaques

Cardiology Clinics, 2009
In many patients, unheralded myocardial infarction associated with a mortality of approximately 20% is the first manifestation of coronary artery disease. Approximately 40% of the population is considered to have a moderate midterm risk of 10% to 20%. Any of the stratification schemes suffers from a lack of accuracy to correctly determine the risk, and
Christoph R. Becker, Tobias Saam
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Progression and regression of the atherosclerotic plaque

European Heart Journal, 1995
In animals in which atherosclerosis was induced experimentally (by a high cholesterol diet) regression of the atherosclerotic lesion was demonstrated after serum cholesterol was reduced by cholesterol- lowering drugs or a low-fat diet. Whether regression of advanced coronary arterly lesions also takes place in humans after a similar intervention ...
P. J. De Feyter, Jaap W. Deckers, Jeroen Vos   +2 more
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The vulnerable atherosclerotic plaque

Emerging Drugs, 1998
Several major clinical trials reported over the past three years have shown that lowering of plasma cholesterol with 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors, or statins, has led to a substantial reduction in clinical events such as heart attack, stroke or death. These striking and encouraging observations were not predicted
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Evolution of the Atherosclerotic Plaque

JAMA, 1964
The evolution of concepts about the arteriosclerotic plaque is brilliantly unfolded in a newly published symposium which ought to be read by all investigators in the field. The articles are of uniformly high standard; the discussions, however, sometimes appear undisciplined.
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Atherosclerotic Plaque

2018
Atherosclerosis is a chronic condition in which several pathophysiological mechanisms contribute to atheromatic plaque creation, which under certain circumstances may lead to life-threatening acute syndromes. Atherosclerotic process seems to be inflammatory initiated disorder that may proceed to an acute clinical event by the induction of plaque ...
Evangelos Oikonomou, Dimitris Tousoulis, Georgios Latsios, Georgia Vogiatzi   +3 more
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Morphology of atherosclerotic plaque

Lasers in Medical Science, 1991
In human pathology the formation, progression and significance of the atherosclerotic plaque are still matter of investigation. Nodular smooth muscle cells hyperplasia with elastic tissue proliferation and subsequent fibrotic transformation are the early intimal changes of the plaque formation.
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The vulnerable and unstable atherosclerotic plaque

Cardiovascular Pathology, 2010
The lesion responsible for the overwhelming majority of acute coronary events is plaque disruption or erosion with superimposed thrombosis. The term "vulnerable plaque" has been used to describe those atherosclerotic plaques that are particularly susceptible to disruption.
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Life and death in the atherosclerotic plaque

Current Opinion in Lipidology, 2010
Changes in cell mass in atherosclerosis represent changes in cell division, cell death and migration/emigration, all of which may be occurring simultaneously in different cell types at different times and in different regions of the plaque. This makes measurement of these individual processes and measurement of overall cell kinetics in atherosclerosis ...
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Development of the Atherosclerotic Plaque

Hospital Practice, 1973
After one has granted that hyperlipidemia and intimal deposition of lipid are primary factors in atherogenesis, the question remains of how to explain the progression to the fully developed, clinically important plaque. The evidence is reviewed that the medial smooth muscle cell, through its proliferation, migration, synthesis of collagen and other ...
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Targeting Atherosclerotic Plaques

2002
Clinical imaging of atherosclerotic plaques is based on anatomical demonstration of the narrowing of the involved artery (1). Angioscopy (2) and intravascular ultrasound (3) can demonstrate the precise location of the lesions, the extent of luminal narrowing and plaque thickening. However, both methods are invasive and cannot provide the composition or
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