Results 31 to 40 of about 503,928 (378)

Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]

, 2020
Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui, Huang, Jiansheng, Huang, Li-Hao, Wang, Dongdong   +3 more
core   +2 more sources

Gene deficiency in activating Fcγ receptors influences the macrophage phenotypic balance and reduces atherosclerosis in mice [PDF]

, 2013
Immunity contributes to arterial inflammation during atherosclerosis. Oxidized low-density lipoproteins induce an autoimmune response characterized by specific antibodies and immune complexes in atherosclerotic patients.
Egido, J., Gomez-Guerrero, C., Lazaro, I., Lopez-Franco, O., Lopez-Parra, V., Lutgens, E., Mallavia, B., Oguiza, A., Ortiz-Muñoz, G., Recio, C.   +9 more
core   +18 more sources

Vulnerable Atherosclerotic Plaque [PDF]

Circulation, 2003
The recent proliferation of invasive and noninvasive techniques to locate vulnerable atherosclerotic plaques raises important questions. Will such techniques add useful prognostic information? If so, will the information prevent myocardial infarction, stroke, or death in at least some patients at risk? Will it lead to new research advances?
Ward, Casscells, Morteza, Naghavi, James T, Willerson   +2 more
openaire   +2 more sources

Single-cell immune landscape of human atherosclerotic plaques

Nature Medicine, 2019
Atherosclerosis is driven by multifaceted contributions of the immune system within the circulation and at vascular focal sites. However, specific characteristics of dysregulated immune cells within atherosclerotic lesions that lead to clinical events ...
Dawn M. Fernandez, Adeeb H. Rahman, Nicolas F. Fernandez, A. Chudnovskiy, E. Amir, L. Amadori, N. Khan, Christine K. Wong, Roza Shamailova, C. Hill, Zichen Wang, R. Remark, Jennifer R. Li, Christian Pina, Christopher M. Faries, Ahmed J Awad, N. Moss, J. Bjorkegren, S. Kim-Schulze, S. Gnjatic, Avi Ma’ayan, J. Mocco, P. Faries, M. Merad, C. Giannarelli   +24 more
semanticscholar   +1 more source

Periopathogens in atherosclerotic plaques of patients with both cardiovascular disease and chronic periodontitis

ARYA Atherosclerosis, 2018
BACKGROUND: Atherosclerosis and periodontitis are both chronic inflammatory diseases. Although a strong relationship between the two has already been established, the underlying mechanism is unknown.
Fazele Atarbashi-Moghadam, Seyed Rohollah Havaei, Seyed Asghar Havaei, Nafiseh Sadat Hosseini, Gholamreza Behdadmehr, Saede Atarbashi-Moghadam   +5 more
doaj   +1 more source

Reduced Necrosis and Content of Apoptotic M1 Macrophages in Advanced Atherosclerotic Plaques of Mice With Macrophage-Specific Loss of Trpc3 [PDF]

, 2017
In previous work we reported that ApoeKO mice transplanted with bone marrow cells deficient in the Transient Receptor Potential Canonical 3 (TRPC3) channel have reduced necrosis and number of apoptotic macrophages in advanced atherosclerotic plaques ...
Birnbaumer, Lutz, Dube, Prabhatchandra R., Solanki, Sumeet, Vazquez, Guillermo   +3 more
core   +1 more source

Quantification of atherosclerotic plaque volume in coronary arteries by computed tomographic angiography in subjects with and without diabetes. [PDF]

, 2020
BackgroundDiabetes mellitus (DM) is considered a cardiovascular risk factor. The aim of this study was to analyze the prevalence and volume of coronary artery plaque in patients with diabetes mellitus (DM) vs. those without DM.MethodsThis study recruited
An, Yun-Qiang, Budoff, Matthew J, Gao, Yang, Hou, Zhi-Hui, Li, Zhen-Nan, Lu, Bin, Yin, Wei-Hua   +6 more
core   +1 more source

Association of some hemostasis and endothelial dysfunction factors with probability of presence of vulnerable atherosclerotic plaques in patients with coronary atherosclerosis

BMC Research Notes, 2019
Objective The study was dedicated to investigation of some hemostasis and endothelial dysfunction factors association with probability of presence of vulnerable atherosclerotic plaques in coronary arteries in men with atherosclerosis.
Yu. I. Ragino, E. V. Striukova, I. S. Murashov, Ya. V. Polonskaya, A. M. Volkov, A. V. Kurguzov, A. M. Chernjavskii, E. V. Kashtanova   +7 more
doaj   +1 more source

Protein S on the surface of plasma lipoproteins: a potential mechanism for protein S delivery to the atherosclerotic plaques?

Bleeding, Thrombosis and Vascular Biology, 2022
The anticoagulant protein S (PS) binds phospholipids with very high affinity, but PS interaction with lipoproteins and lipidrich atherosclerotic plaques remains still poorly defined.
Marcello Baroni, Paolo Ferraresi, Nicole Ziliotto, Daria Bortolotti, Pierfilippo Acciarri, Nicola Martinelli, Giovanna Marchetti, Matteo Coen, Francesco Bernardi   +8 more
doaj   +1 more source

Genetic susceptibility loci for cardiovascular disease and their impact on atherosclerotic plaques [PDF]

, 2018
Background: Atherosclerosis is a chronic inflammatory disease in part caused by lipid uptake in the vascular wall, but the exact underlying mechanisms leading to acute myocardial infarction and stroke remain poorly understood. Large consortia identified
Asselbergs, Folkert W, Björkegrenn, Johan L.M, de Bakker, Paul I.W, de Borst, Gert J., den Ruijter, Folkert W, Dichgans, Martin, Erdmann, Jeanette, Ford, Ian, Foroughi Asl, Hassan, Haitjema, Saskia, Hedin, Ulf, Malik, Rainer, Mokry, Michal, Pasterkamp, Gerard, Paulsson-Berne, Gabrielle, Perisic, Ljubica, Samani, Nilesh J, Sattar, Naveed, Schunkert, Heribert, Siemelink, Marten A., Stott, David J., van der Laan, Sander W., van Setten, Jessica, Worrall, Bradford B   +23 more
core   +2 more sources