Results 101 to 110 of about 657,034 (319)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim   +4 more
wiley   +1 more source

ATLAS events - 2016 p+Pb run [PDF]

open access: yes, 2016
ATLAS events selected in the analysis of proton Pb collisions at 8.16 TeV, November ...
ATLAS Collaboration
core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

ATLAS Event Display: Light Scattering Off Light [PDF]

open access: yes, 2019
ATLAS event display showing the clean signature of light-by-light ...
ATLAS Collaboration
core  

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

3-7 Yaş Arası Besin Alerjisi, Astım veya Saman Nezlesi Bulunan Çocuklarda Dil ve Konuşma Becerilerinin Değerlendirilmesi

open access: yesDil, Konuşma ve Yutma Araştırmaları Dergisi
Amaç: Bu çalışmanın amacı, 3-7 yaş arası randomize seçilen besin, astım ve saman nezlesi alerjilerinden herhangi birine sahip çocukların genel gelişimleri, alıcı ve ifade edici dil, sesletim ve motor konuşma becerilerini incelemektir.Yöntem: Araştırmaya ...
Ferhat Korkmaz   +3 more
doaj   +1 more source

ATLAS data-taking milestone: 1EB of data [PDF]

open access: yes
ATLAS enters the exascale! The ATLAS experiment has 1 EB (1 billion billion bytes) of real and simulated data worldwide, managed using ...
ATLAS Collaboration
core  

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

ATLAS Blog: The Ties That Bind [PDF]

open access: yes, 2014
Photos accompanying the ATLAS Blog "The Ties That Bind" by Steven Goldfarb, 14 Jan 2015.
ATLAS Collaboration
core  

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