Results 101 to 110 of about 1,855,991 (308)
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Dil, Konuşma ve Yutma Araştırmaları DergisiAmaç: Bu çalışmanın amacı, 3-7 yaş arası randomize seçilen besin, astım ve saman nezlesi alerjilerinden herhangi birine sahip çocukların genel gelişimleri, alıcı ve ifade edici dil, sesletim ve motor konuşma becerilerini incelemektir.Yöntem: Araştırmaya ...
Ferhat Korkmaz +3 more
doaj +1 more source
The Higgs discovery potential of ATLAS [PDF]
, 2007 Higgs boson production and decay at the LHC is described, together with related ATLAS search channels, in order to provide an overview of the ATLAS Higgs discovery potential.Comment: 6 ...
Collins-Tooth, Christopher
core +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Spectral atlases of the Sun from 3980 to 7100 {\AA} at the center and at the limb
, 2014 In this work, we present digital and graphical atlases of spectra of both the solar disk-center and of the limb near the Solar poles using data taken at the UTS-IAP & RIAAM (the University of Tabriz Siderostat, telescope and spectrograph jointly ...
Ajabshirizadeh, Ali +2 more
core +2 more sources
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Electron/Photon identification in ATLAS and CMS [PDF]
, 2006 Recent studies in ATLAS and CMS experiments for the reconstruction and identification of electrons and photons using full Monte Carlo and testbeam data are reportedComment: Talk given at the Hadron Collider Physic Symposium 2006 (HCP2006), Durham, NC ...
Charlot, C.
core +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source