Results 91 to 100 of about 892,504 (360)

Railway, postal & telegraph map of Queensland 1888 [cartographic material] /

, 1888
Map of Queensland showing railways, places with postal and telegraph services and average annual rainfall. Has index to towns.; Folded map from Vol. 2 of: Picturesque Atlas of Australasia. Sydney : Picturesque Atlas Publishing Company, Limited, 1886-1889.
Picturesque Atlas Publishing Company.
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Integrating gene expression and proteomics for breast cancer biomarker prediction through a deep learning framework with SHAP-based explainability

Discover Artificial Intelligence
This study presents a deep learning framework that integrates gene expression and proteomic-proxy features to predict breast cancer biomarkers ER, PR, and HER2.
Naim Ajlouni, Abdelrahman Almassri
doaj   +1 more source

A molecular cell atlas of the human lung from single cell RNA sequencing

Nature, 2019
Although single-cell RNA sequencing studies have begun to provide compendia of cell expression profiles1–9, it has been difficult to systematically identify and localize all molecular cell types in individual organs to create a full molecular cell atlas.
K. Travaglini, Ahmad N. Nabhan, L. Penland, Rahul Sinha, A. Gillich, R. Sit, Stephen Chang, Stephanie D. Conley, Y. Mori, J. Seita, G. Berry, J. Shrager, Ross J. Metzger, Christin S Kuo, N. Neff, I. Weissman, S. Quake, M. Krasnow   +17 more
semanticscholar   +1 more source

Railway postal and telegraph map of the North Island, New Zealand 1889 [cartographic material] /

, 1889
Map of the North Island of New Zealand showing railways, railway stations, post and telegraph offices and postal routes. Relief shown by hachures.; From Vol. 3 of: Picturesque atlas of Australasia.
Picturesque Atlas Publishing Company
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MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Determination of the Relationship Between Voice and Swallowing Characteristics in Individuals aged 65 and Over with Sarcopenia Risk

The Turkish Journal of Ear Nose and Throat
Objective: Sarcopenia, which increases with age, causes a decrease in muscle mass and strength, potentially leading to changes in the voice’s acoustic, perceptual, and aerodynamic parameters, as well as dysphagia. This study aimed to assess the voice and
Serkan Bengisu, Aynur İkra Demir
doaj   +1 more source

Railway, postal and telegraph map of the Middle Island, New Zealand [cartographic material] /

, 1889
Map of the South Island of New Zealand showing railways, railway stations, post and telegraph offices and postal routes. Relief shown by hachures.; From Vol. 3 of: Picturesque atlas of Australasia.
Picturesque Atlas Publishing Company.
core  

ATLAS Event Displays: Horizontal Muons

, 2023
Event displays (Run 449604, Event 228336, Beam 1) containing horizontal muons recorded by the ATLAS experiment during a special run for detector calibration on 18 April ...
ATLAS Collaboration
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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source