Results 221 to 230 of about 1,930,055 (355)

The FinnBrain multimodal neonatal template and atlas collection. [PDF]

open access: yesCommun Biol
Tuulari JJ   +18 more
europepmc   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

open access: yesAdvanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao   +14 more
wiley   +1 more source

A network correspondence toolbox for quantitative evaluation of novel neuroimaging results. [PDF]

open access: yesNat Commun
Kong R   +21 more
europepmc   +1 more source

Genomic atlas of the human plasma proteome

open access: yesNature, 2018
B. Sun   +32 more
semanticscholar   +1 more source

The Allen Mouse Brain Common Coordinate Framework: A 3D Reference Atlas

open access: yesCell, 2020
Quanxin Wang   +5 more
semanticscholar   +1 more source

Malignant Hepatoblast‐Like Cells Sustain Stemness via IGF2‐Dependent Cholesterol Accumulation in Hepatoblastoma

open access: yesAdvanced Science, EarlyView.
Hepatoblastoma, an aggressive childhood liver tumor, origins from malignant hepatoblast‐like cells. Single‐cell analysis reveals IGF2‐driven pathways promoting malignancy. Targeting these pathways offers promising treatments, with serum IGF2 as a potential diagnostic biomarker.
Miao Ding   +12 more
wiley   +1 more source

GRP78 Nanobody‐Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy

open access: yesAdvanced Science, EarlyView.
A GRP78 nanobody‐directed immunotoxin suppresses cancer progression and metastasis by enhancing antitumor immunity via STING pathway activation, offering a pan‐cancer‐targeted approach and immunotherapy combination strategy. Abstract The lack of targetable antigens poses a significant challenge in developing effective cancer‐targeted therapies.
Huifang Wang   +16 more
wiley   +1 more source

IDF Diabetes Atlas: Global estimates for the prevalence of diabetes for 2015 and 2040.

open access: yesDiabetes Research and Clinical Practice, 2011
K. Ogurtsova   +10 more
semanticscholar   +1 more source

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