Results 241 to 250 of about 1,930,055 (355)

The Awakening Brain is Characterized by a Widespread and Spatiotemporally Heterogeneous Increase in High Frequencies

open access: yesAdvanced Science, EarlyView.
This work explores the process of morning awakening of the human brain using polysomnography paired with simultaneous stereo‐electroencephalography, a method that provides high spatial and temporal resolution for examining brain activity. Awakening is characterized by an increase in high‐frequency spectral power and connectivity.
Tamir Avigdor   +5 more
wiley   +1 more source

Inhibition of RACK1‐Mediated NLRP3 Oligomerization (Active Conformation) Ameliorates Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Schematic diagram showing the potential mechanism of bigelovin on the activation of NLRP3 inflammasome Bigelovin may inhibit activated protein C kinase 1 (RACK1) by directly binding with cys168 of RACK1. Bigelovin thus prevents oligomerization of NLRP3 (NLRP3 active conformation) and subsequent assembly of NLRP3 inflammasome, blocking the activation of
Jian Cui   +17 more
wiley   +1 more source

A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing

open access: yesCell, 2007
P. Landgraf   +50 more
semanticscholar   +1 more source

A single-cell transcriptomic atlas characterizes ageing tissues in the mouse

open access: yesNature, 2020
Nicole Jane Ankit S. Isaac Ishita Ben A. Philip A. Daniel Almanzar Antony Baghel Bakerman Bansal Barres Beac   +134 more
semanticscholar   +1 more source

Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

open access: yesAdvanced Science, EarlyView.
VPS72 overexpression activates mTORC1 signaling, subsequently promoting lipid synthesis and driving HCC progression. VPS72 modulates the epigenetic landscape of ATF3 promoter, such as H2A.Z acetylation reduction and DNA methylation increase, which results in ATF3 repression and subsequent activation of mTORC1.
Qinglin Zhang   +4 more
wiley   +1 more source

Espacio peridural en paciente obesa gestante [PDF]

open access: yesRevista Chilena de Anestesia
Pablo Santillán Roldán   +5 more
doaj   +1 more source

Identification of leukemia-enriched signature through the development of a comprehensive pediatric single-cell atlas. [PDF]

open access: yesNat Commun
Mumme HL   +12 more
europepmc   +1 more source

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