Results 21 to 30 of about 756,779 (220)

Vinorelbine- Autophagy Agent Combinations Induce Synergistic Cytotoxicity in SH-SY5Y Neuroblastoma Cells

open access: yesRecent Trends in Pharmacology
Objective: To investigate whether pharmacological agents associated with autophagy induction or inhibition modulate vinorelbine-induced cytotoxic responses in SH-SY5Y neuroblastoma cells.
Berna Yıldırım   +5 more
doaj   +1 more source

Short bowel syndrome after near total enterectomy in an elderly patient: case report and review of the literature [PDF]

open access: yesExploration of Digestive Diseases
Acute mesenteric ischemia (AMI) is a rare but highly lethal vascular emergency resulting from the abrupt interruption of intestinal blood flow. In advanced stages, extensive bowel necrosis may require near total enterectomy, leading to short bowel ...
Emine Yildirim   +7 more
doaj   +1 more source

Low discontinuation rate of tirzepatide treatment in Japanese patients with diabetes mellitus; importance of traditional Japanese diet

open access: yesJournal of Health, Population and Nutrition
Tirzepatide, a novel dual GIP and GLP-1 receptor agonist, has demonstrated robust efficacy in clinical trials; however, discontinuation rates due to gastrointestinal adverse events have been reported at 6–10% in Western populations. In contrast, our real-
Takahiro Hiraide   +4 more
doaj   +1 more source

Impact of Parkinson's Disease-Related Dysphagia Severity on Quality of Life: Comparison Between Self-Reports and Videofluoroscopic Swallowing Study Results

open access: yesThe Turkish Journal of Ear Nose and Throat
Objective: The aim of this study was to evaluate the impact of dysphagia due to Parkinson's disease (PD) on quality of life and to compare the results of the objective assessment with those of patient self-reports.Materials and Methods: The study ...
Serkan Bengisu   +5 more
doaj   +1 more source

Pattern Atlas [PDF]

open access: yes, 2021
Pattern languages are well-established in the software architecture community. Many different aspects of creating a software architecture are addressed by such languages. Thus, several pattern languages have to be considered when building a particular architecture. But these pattern languages are isolated, i.e.
Frank Leymann, Johanna Barzen
openaire   +3 more sources

Corrección de mielomeningocele intrautero: Reporte del primer caso en Ecuador [PDF]

open access: yesRevista Chilena de Anestesia, 2021
Pablo Santillán Roldán   +5 more
doaj   +1 more source

Validación de la posición de Vallejo por ultrasonografía para acceso neuroaxial difícil en pacientes obstétricas [PDF]

open access: yesRevista Chilena de Anestesia, 2022
Pablo Santillán Roldan   +5 more
doaj   +1 more source

Clinical and Biological Significances of a Methyltransferase-Related Signature in Diffuse Glioma

open access: yesFrontiers in Oncology, 2020
Methylation of DNA, RNA or protein is a reversible modification. The proteins and genes that regulate this modification can be a candidate target for tumor therapy. However, the characteristics of methyltransferase related genes in glioma remain obscure.
Ying Zhang   +11 more
doaj   +1 more source

Global estimation of anti-malarial drug effectiveness for the treatment of uncomplicated Plasmodium falciparum malaria 1991–2019

open access: yesMalaria Journal, 2020
Background Anti-malarial drugs play a critical role in reducing malaria morbidity and mortality, but their role is mediated by their effectiveness.
Giulia Rathmes   +24 more
doaj   +1 more source

PTPRZ1-MET FUsion GENe (ZM-FUGEN) trial: study protocol for a multicentric, randomized, open-label phase II/III trial

open access: yesChinese Neurosurgical Journal, 2023
Background PTPRZ1-MET fusion was reported to associate with glioma progression from low-grade to high-grade glioma, which was a target by a MET inhibitor vebreltinib.
Zhaoshi Bao   +7 more
doaj   +1 more source

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