Results 41 to 50 of about 422,726 (219)

A malaria seasonality dataset for sub-Saharan Africa

open access: yesScientific Data
Malaria imposes a significant global health burden and remains a major cause of child mortality in sub-Saharan Africa. In many countries, malaria transmission varies seasonally.
Francesca Sanna   +23 more
doaj   +1 more source

Mapping malaria seasonality in Madagascar using health facility data

open access: yesBMC Medicine, 2020
Background Many malaria-endemic areas experience seasonal fluctuations in case incidence as Anopheles mosquito and Plasmodium parasite life cycles respond to changing environmental conditions.
Michele Nguyen   +19 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Quality and reliability of YouTube videos on breast engorgement

open access: yesInternational Breastfeeding Journal
Background Breast engorgement is a common and painful condition that can lead to the early cessation of breastfeeding. Many mothers turn to online platforms like YouTube for information and support, but the quality of this content is often unverified ...
Şehma Şen   +2 more
doaj   +1 more source

Identifying mental health status using deep neural network trained by visual metrics

open access: yesTranslational Psychiatry, 2020
Mental health is an integral part of the quality of life of cancer patients. It has been found that mental health issues, such as depression and anxiety, are more common in cancer patients. They may result in catastrophic consequences, including suicide.
Somayeh B. Shafiei   +4 more
doaj   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Heavy-Ions collide in the ATLAS Experiment

open access: yes, 2023
First ATLAS heavy-ion-collision event displays of ...
ATLAS Collaboration
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Northern Territory of South Australia [cartographic material]

open access: yes, 1886
Map of the Northern Territory showing places named after British Prime Ministers and parliamentarians. Relief shown by hachures.; Prime meridian: Greenwich.; From: Picturesque atlas of Australasia.
Picturesque Atlas Publishing Company.
core  

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