Results 51 to 60 of about 892,504 (360)
The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).Grazyna Debska‐Vielhaber, Niki Karavasili, Matthias Kunz, Zemfira Gizatullina, Timur Gainutdinov, Stefan Vielhaber, Wolfram S. Kunz, Frank N. Gellerich +7 morewiley +1 more sourceClinical and Biological Significances of a Methyltransferase-Related Signature in Diffuse Glioma
Frontiers in Oncology, 2020 Methylation of DNA, RNA or protein is a reversible modification. The proteins and genes that regulate this modification can be a candidate target for tumor therapy. However, the characteristics of methyltransferase related genes in glioma remain obscure. Ying Zhang, Ying Zhang, Yuqing Liu, Yuqing Liu, Hanjie Liu, Hanjie Liu, Zheng Zhao, Zheng Zhao, Fan Wu, Fan Wu, Fan Zeng, Fan Zeng +11 moredoaj +1 more sourceSubtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan +6 morewiley +1 more sourceGlobal estimation of anti-malarial drug effectiveness for the treatment of uncomplicated Plasmodium falciparum malaria 1991–2019
Malaria Journal, 2020 Background Anti-malarial drugs play a critical role in reducing malaria morbidity and mortality, but their role is mediated by their effectiveness.Giulia Rathmes, Susan F. Rumisha, Tim C. D. Lucas, Katherine A. Twohig, Andre Python, Michele Nguyen, Anita K. Nandi, Suzanne H. Keddie, Emma L. Collins, Jennifer A. Rozier, Harry S. Gibson, Elisabeth G. Chestnutt, Katherine E. Battle, Georgina S. Humphreys, Punam Amratia, Rohan Arambepola, Amelia Bertozzi-Villa, Penelope Hancock, Justin J. Millar, Tasmin L. Symons, Samir Bhatt, Ewan Cameron, Philippe J. Guerin, Peter W. Gething, Daniel J. Weiss +24 moredoaj +1 more sourcePTPRZ1-MET FUsion GENe (ZM-FUGEN) trial: study protocol for a multicentric, randomized, open-label phase II/III trial
Chinese Neurosurgical Journal, 2023 Background PTPRZ1-MET fusion was reported to associate with glioma progression from low-grade to high-grade glioma, which was a target by a MET inhibitor vebreltinib.Zhaoshi Bao, Shouwei Li, Liang Wang, Bisi Zhang, Peilong Zhang, Hepeng Shi, Xiaoguang Qiu, Tao Jiang +7 moredoaj +1 more sourceThe ATLAS Collaboration
Nuclear Physics A, 2009 Contains fulltext : 119348.pdf (Publisher’s version ) (Open Access)G. Aad, T. Abajyan, B. Abbott, J. Abdallah, S. Abdel Khalek, A.A. Abdelalim, O. Abdinov, R. Aben, B. Abi, O.S. AbouZeid, H. Abramowicz, H. Abreu, B.S. Acharya, L. Adamczyk, D.L. Adams, T.N. Addy, J. Adelman, S. Adomeit, T. Adye, S. Aefsky, J.A. Aguilar-Saavedra, M. Agustoni, M. Aharrouche, S.P. Ahlen, A. Ahmad, M. Ahsan, G. Aielli, T. Akdogan, T.P.A. Åkesson, G. Akimoto, A.V. Akimov, M.S. Alam, M.A. Alam, J. Albert, S. Albrand, M. Aleksa, I.N. Aleksandrov, C. Alexa, G. Alexander, G. Alexandre, T. Alexopoulos, M. Alhroob, M. Aliev, G. Alimonti, J. Alison, B.M.M. Allbrooke, P.P. Allport, S.E. Allwood-Spiers, J. Almond, A. Aloisio, R. Alon, A. Alonso, F. Alonso, A. Altheimer, B. Alvarez Gonzalez, M.G. Alviggi, C. Amelung, S.P. Amor Dos Santos, A. Amorim, N. Amram, C. Anastopoulos, L.S. Ancu, N. Andari, T. Andeen, C.F. Anders, G. Anders, K.J. Anderson, A. Andreazza, V. Andrei, X.S. Anduaga, S. Angelidakis, P. Anger, A. Angerami, F. Anghinolfi, A. Anisenkov, N. Anjos, A. Annovi, A. Antonaki, M. Antonelli, A. Antonov, J. Antos, F. Anulli, M. Aoki, S. Aoun, L. Aperio Bella, R. Apolle, G. Arabidze, I. Aracena, Y. Arai, A.T.H. Arce, S. Arfaoui, J-F. Arguin, S. Argyropoulos, M. Arik, A.J. Armbruster, O. Arnaez, V. Arnal, C. Arnault, A. Artamonov, G. Artoni, D. Arutinov, S. Asai, S. Ask, B. Åsman, L. Asquith, K. Assamagan, M. Atkinson, K. Augsten, M. Aurousseau, G. Avolio, R. Avramidou, G. Azuelos, Y. Azuma, M.A. Baak, A.M. Bach, H. Bachacou, K. Bachas, M. Backes, M. Backhaus, J. Backus Mayes, E. Badescu, P. Bagnaia, S. Bahinipati, Y. Bai, T. Bain, J.T. Baines, O.K. Baker, S. Baker, P. Balek, E. Banas, P. Banerjee, Sw. Banerjee, D. Banfi, A. Bangert, V. Bansal, H.S. Bansil, L. Barak, A. Barbaro Galtieri, T. Barber, E.L. Barberio, D. Barberis, M. Barbero, T. Barillari, M. Barisonzi, T. Barklow, N. Barlow, B.M. Barnett, R.M. Barnett, A. Baroncelli, G. Barone, A.J. Barr, F. Barreiro, J. Barreiro Guimarães da Costa, P. Barrillon, R. Bartoldus, A.E. Barton, V. Bartsch, A. Basye, R.L. Bates, L. Batkova, J.R. Batley, A. Battaglia, M. Battistin, F. Bauer, H.S. Bawa, S. Beale, T. Beau, P.H. Beauchemin, R. Beccherle, P. Bechtle, H.P. Beck, A.K. Becker, S. Becker, M. Beckingham, A.J. Beddall, A. Beddall, S. Bedikian, V.A. Bednyakov, C.P. Bee, L.J. Beemster, M. Begel, S. Behar Harpaz, M. Beimforde, C. Belanger-Champagne, P.J. Bell, W.H. Bell, G. Bella, L. Bellagamba, M. Bellomo, A. Belloni, O. Beloborodova, K. Belotskiy, O. Beltramello, O. Benary, D. Benchekroun, K. Bendtz, N. Benekos, Y. Benhammou, E. Benhar Noccioli, J.A. Benitez Garcia, M. Benoit, R.M. Bianchi, P.A. Bruckman de Renstrom, J. Buchanan, D. Caforio, O. Cakir, P. Calafiura, F. Canelli, M. Capua, J. Carvalho, D. Casadei, N.F. Castro, A.S. Cerqueira, S. Cheatham, G. Chiodini, A.K. Ciftci, M. Cobal, A. Coccaro, P. Conde Muiño, G. Darbo, S. De Cecco, M. Della Pietra, D. della Volpe, B. Demirkoz, B. Di Girolamo, A. Di Mattia, R. Di Nardo, M.A.B. do Vale, Z. Dolezal, A. Doria, M. Dwuznik, E. Etzion, L. Fabbri, P. Federic, J. Ferrando, M.C.N. Fiolhais, L. Fiorini, I. Fleck, P. Francavilla, E. Fullana Torregrosa, J. Fuster, M. Garcia-Sciveres, B. Giacobbe, S. Giagu, S.M. Gibson, M.P. Giordani, R. Giordano, A. Gomes, S. Gonzalez-Sevilla, E. Gorini, E. Gornicki, M. Gouighri, V. Grassi, T. Greenshaw, C.B. Gwilliam, S. Hassani, M.C. Hodgkinson, Z. Hubacek, D. Iliadis, S. Istin, J.M. Izen, V. Izzo, R.W.L. Jones, A.N. Karyukhin, K. Kawagoe, M. Keil, E.B. Klinkby, P. Kodys, R. Konoplich, N. Konstantinidis, J. Kretzschmar, L. La Rotonda, C. Lacasta, T. Lagouri, E. Lancon, J.S.H. Lee, F. Legger, R. Leitner, Z. Liang, M. Losada, A. Maio, F. Malek, J. Mamuzic, J. Maneira, F. Marroquim, S. Martin-Haugh, R. Mazini, E. Meoni, P. Mermod, A. Messina, S. Migas, M. Miñano Moya, V.A. Mitsou, R.W. Moore, D. Moreno, P. Morettini, E. Musto, G. Navarro, S. Oda, A. Olszewski, J. Olszowska, D. Orestano, I. Orlov, B. Osculati, A. Pacheco Pages, C. Padilla Aranda, G. Pásztor, M.I. Pedraza Morales, S.V. Peleganchuk, L. Perini, F. Petrucci, J. Pina, J. Poveda, R. Pravahan, D. Price, F. Prokoshin, S. Psoroulas, F. Quinonez, P. Reznicek, L. Rinaldi, A. Romaniouk, L. Roos, I. Sadeh, G. Salamanna, A. Salamon, A. Salzburger, J.G. Saraiva, C. Schiavi, G. Siragusa, O. Smirnova, S. Spagnolo, F. Spanò, T. Sykora, G.F. Tartarelli, P. Teixeira-Dias, K. Tokushuku, I.M. Trigger, A. Trzupek, B. Vachon, J.A. Valls Ferrer, S. Veneziano, A. Ventura, V. Vercesi, I. Vivarelli, M. Volpi, M. Vos, J.H. Vossebeld, M.W. Wolter, H. Wolters, B. Wrona, A. Zhemchugov +350 moreopenaire +9 more sourcesMolecularly defined and spatially resolved cell atlas of the whole mouse brain
Nature, 2023 A comprehensive cell atlas of the whole mouse brain with high molecular and spatial resolution is generated. In mammalian brains, millions to billions of cells form complex interaction networks to enable a wide range of functions.Meng Zhang, Xingjie Pan, Won Jung, Aaron R Halpern, Stephen W. Eichhorn, Zhiyun Lei, Limor Cohen, Kimberly A. Smith, Bosiljka Tasic, Z. Yao, Hongkui Zeng, X. Zhuang +11 moresemanticscholar +1 more source