Automated cervix biometry, volumetry and normative models for 3D motion-corrected T2-weighted 0.55-3T fetal MRI during 2nd and 3rd trimesters. [PDF]
Uus A +8 more
europepmc +1 more source
Atlas of Human Anatomy, 5th ed., Vols 1 & 2, Petra Köpf-Maier : book review
Damon Bizos
openalex +1 more source
Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li +18 more
wiley +1 more source
Diffuse Idiopathic Skeletal Hyperostosis of Upper Cervical Vertebrae: A Case Report of a Rare Anatomical Presentation During Bone Retrieval. [PDF]
Thirumaran B, Dsouza Dias M.
europepmc +1 more source
This study elucidates how DCAF12 facilitates non‐degradative ubiquitination to stabilize TRiC/CCT, thereby enhancing the folding capacity of chaperonins. This mechanism promotes the maturation of cytoskeletal proteins and activates key oncogenic drivers, including YAP, STAT3, and mTOR, ultimately driving metastatic progression in lung cancer.
Zhenyi Wang +13 more
wiley +1 more source
Identification, structural features, and potential functional significance of the myodural Bridge in African clawed frog, the Xenopus laevis. [PDF]
Yang H +16 more
europepmc +1 more source
LZU‐WZLYCS01 is a novel FGFR3‐targeting ADC for bladder cancer with 7‐ethyl‐9‐fluorocamptothecin (A2) as its cytotoxic payload. LZU‐WZLYCS01 intracellularly releases A2, which targets MAD2L1 to activate the cGAS‐STING pathway and induce tumor cell apoptosis.
Shu Cui +16 more
wiley +1 more source
Solving the where problem and quantifying geometric variation in neuroanatomy using generative diffeomorphic mapping. [PDF]
Tward DJ +9 more
europepmc +1 more source
Geometrically Encoded Positioning of Introns, Intergenic Segments, and Exons in the Human Genome
This study introduces a new hypothesis: exons, introns, and intergenic segments are non‐random projections of the functional layers of 3D structure of chromatin packing domains. Evidence is presented that this “geometric code” may encode volumetric structure, reconciling epigenetic patterns, correlates with oncogenic mutations, acting as a potential ...
Luay M. Almassalha +11 more
wiley +1 more source

