Results 251 to 260 of about 596,401 (334)

Structural Connectivity Differences Reflect Microstructural Heterogeneity of the Human Insular Cortex. [PDF]

Hum Brain Mapp
Quabs J, Bittner N, Caspers S.
europepmc   +1 more source

SNORA74A Drives Self‐Renewal of Liver Cancer Stem Cells and Hepatocarcinogenesis Through Activation of Notch3 Signaling

Advanced Science, EarlyView.
Abstract Liver cancer stem cells (CSCs) account for tumor initiation, heterogeneity and therapy resistance. However, the role of small nucleolar RNAs (snoRNAs) in the regulation of liver CSCs remains largely unclear. Here, this work identifies a conserved H/ACA box snoRNA SNORA74A which is highly expressed in liver CSCs.
Ziheng Zhou, Yang Gu, Zhibin Yi, Jianyi Wang, Zhen Xiong, Hui Guo, Ying Du, Xiaoxiao Zhu, Lei He, Weizheng Ren, Yong Tian, Yanying Wang, Zusen Fan   +12 more
wiley   +1 more source

Zebrafishology, study design guidelines for rigorous and reproducible data using zebrafish. [PDF]

Commun Biol
Bedell VM, Dubey P, Lee HB, Bailey DS, Anderson JL, Jamieson-Lucy A, Xiao R, Leonard EV, Falk MJ, Pack MA, Mullins M, Farber SA, Eckenhoff RG, Ekker SC.   +13 more
europepmc   +1 more source

Pancreatic Cancer‐Derived Extracellular Vesicles Enriched with miR‐223‐5p Promote Skeletal Muscle Wasting Associated with Cachexia

Advanced Science, EarlyView.
EVs and EV‐microRNAs (miRNAs) mediate PDAC‐skeletal muscle communication. miR‐223‐5p reduces METTL14 transcription by targeting MAFA, which subsequently decreases m6A methylation in skeletal muscles, ultimately leading to muscle wasting. This study highlights the absorption of miRNA in PDAC‐derived EVs by skeletal muscles and reveals a previously ...
Kangjing Xu, Rongxi Shen, Li Zhang, Xuejin Gao, Xinbo Wang, Changhua Zhang, Xi Chen, Xinying Wang   +7 more
wiley   +1 more source

Automated cell annotation in multi-cell images using an improved CRF_ID algorithm. [PDF]

Elife
Lee HJ, Liang J, Chaudhary S, Moon S, Yu Z, Wu T, Liu H, Choi MK, Zhang Y, Lu H.   +9 more
europepmc   +1 more source

Advancing Soil Organic Carbon Prediction: A Comprehensive Review of Technologies, AI, Process‐Based and Hybrid Modelling Approaches

Advanced Science, EarlyView.
This review highlights advances in soil organic carbon (SOC) quantification using remote sensing, proximal soil sensing, AI (ML and DL), and biogeochemical modelling. Integrating diverse data sources and models improves SOC prediction accuracy. Key priorities include enhancing data availability, refining models, incorporating microbial processes, and ...
Zijuan Ding, Ke Liu, Sabine Grunwald, Pete Smith, Philippe Ciais, Bin Wang, Alexandre M.J.‐C. Wadoux, Carla Ferreira, Senani Karunaratne, Narasinha Shurpali, Xiaogang Yin, Dale Roberts, Oli Madgett, Sam Duncan, Meixue Zhou, Zhangyong Liu, Matthew Tom Harrison   +16 more
wiley   +1 more source

Sœmmerring's error: the root of the story. The C8 nerve is a misconception. A historical review and anatomical perspectives. [PDF]

Front Neuroanat
Chaynes P, Carfagna L, Poinsignon M, De Barros A.   +3 more
europepmc   +1 more source

Neutrophil‐Mimicking Nanomedicine Eliminates Tumor Intracellular Bacteria and Enhances Chemotherapy on Liver Metastasis of Colorectal Cancer

Advanced Science, EarlyView.
Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu, Xu Zhao, Yong Li, Xiaoya Ma, Weifeng Yang, Jie Ma, Wanglin Li, Wei Yuan   +7 more
wiley   +1 more source

Locating eloquent sites identified during brain tumor intraoperative mapping on reference MRI atlas. [PDF]

Commun Med (Lond)
Elia A, Roux A, Debacker C, Charron S, Simboli G, Moiraghi A, Trancart B, Dezamis E, Muto J, Chretien F, Zanello M, Oppenheim C, Pallud J.   +12 more
europepmc   +1 more source

An Annotated Multi-Site and Multi-Contrast Magnetic Resonance Imaging Dataset for the study of the Human Tongue Musculature. [PDF]

Sci Data
Ribeiro FL, Zhu X, Ye X, Tu S, Ngo ST, Henderson RD, Steyn FJ, Kiernan MC, Barth M, Bollmann S, Shaw TB.   +10 more
europepmc   +1 more source