Results 71 to 80 of about 596,401 (334)

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

El Atlas Anatómico de la Facultad de Medicina de la Universidad de Zaragoza. La recuperación de una pieza importante del patrimonio histórico universitario. [PDF]

Pecia Complutense, 2012
La Universidad de Zaragoza puede honrarse de poseer dos piezas excepcionales, fruto del genio de los dos aragoneses más universales: un ejemplar de la primera edición de los Caprichos de Goya con comentarios manuscritos y el Atlas de Anatomía de Cajal ...
Moralejo Álvarez, María Remedios
doaj  

EFFECT ON ACADEMIC PERFORMANCE BY LEARNING ONLINE THROUGH 3D ANATOMY ATLAS VERSUS 2D PRESENTATIONS

Pakistan Armed Forces Medical Journal, 2021
Objective: To assess the effect of using a 3-D atlas on academic performance and compare it with the use of power point presentations during online lectures for gross anatomy of the head. Study Design: Comparative prospective study.
Ayesha Haque, Ruqqia Shafi, Tayyaba Faisal, Sajida Naseem, Salma Ambreen, Aisha Rafi   +5 more
doaj  

An atlas of white matter anatomy, its variability, and reproducibility based on constrained spherical deconvolution of diffusion MRI

NeuroImage, 2021
A. Radwan, S. Sunaert, K. Schilling, M. Descoteaux, B. Landman, M. Vandenbulcke, T. Theys, P. Dupont, L. Emsell   +8 more
semanticscholar   +1 more source

A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang, Da Lin, Dongyuan Liu, Dongxu Zhang, Hao Wang   +4 more
wiley   +1 more source

Craniovertebral junction 360°: A combined microscopic and endoscopic anatomical study

Journal of Craniovertebral Junction and Spine, 2016
Objectives: Craniovertebral junction (CVJ) can be approached from various corridors depending on the location and extent of disease. A three dimensional understanding of anatomy of CVJ is paramount for safe surgery in this region.
Sukhdeep Singh Jhawar, Maximiliano Nunez, Paolo Pacca, Daniel Seclen Voscoboinik, Huy Truong   +4 more
doaj   +1 more source

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden, Charles Carron, Donatienne Van Weehaeghe, Joke De Vocht, Fouke Ombelet, Pegah Masrori, Caro De Weerdt, Rebecca E. James, Lauren T. Evans, Frederick A. Schroeder, Jacob M. Hooker, Michel Koole, Janice E. Kranz, Tonya M. Gilbert, Philip Van Damme, Koen Van Laere   +15 more
wiley   +1 more source

A comparison of Freesurfer and multi-atlas MUSE for brain anatomy segmentation: Findings about size and age bias, and inter-scanner stability in multi-site aging studies

NeuroImage, 2020
Automatic segmentation of brain anatomy has been a key processing step in quantitative neuroimaging analyses. An extensive body of literature has relied on Freesurfer segmentations.
Dhivya Srinivasan, Guray Erus, Jimit Doshi, David A. Wolk, Haochang Shou, Mohamad Habes, Christos Davatzikos   +6 more
doaj  

Glycosylation Gene Signatures as Prognostic Biomarkers in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioblastoma (GBM) is an aggressive brain tumor characterized by significant heterogeneity. This study investigates the role of glycosylation‐related genes in GBM subtyping, prognosis, and response to therapy. Methods We analyzed mRNA expression data and clinical information from The Cancer Genome Atlas (TCGA) and Gene Expression ...
Tong Zhao, Hongliang Ge, Chenchao Lin, Xiyue Wu, Jianwu Chen   +4 more
wiley   +1 more source