Results 91 to 100 of about 957,277 (312)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Las intervenciones del psicoterapeuta: Estudio comparativo en un grupo psicoterapéutico psicoanalítico de niños y en un grupo de orientación a sus respectivos padres o adultos responsables Psychotherapist's interventions: comparative study on a psychotherapy psychoanalytic group of child and on an orientation group for their parents or responsible adults

Anuario de Investigaciones, 2010
Se presentan resultados parciales de un proyecto de investigación en el que se realiza un análisis cuantitativo y cualitativo de las "intervenciones del psicoterapeuta" en un grupo psicoterapéutico de niños entre 6 y 8 años y en el grupo de orientación a
Tatiana Carusi, Sara Slapak
doaj  

A multiomic atlas identifies a treatment-resistant, bone marrow progenitor-like cell population in T cell acute lymphoblastic leukemia

Nature Cancer
Refractoriness to initial chemotherapy and relapse after remission are the main obstacles to curing T cell acute lymphoblastic leukemia (T-ALL). While tumor heterogeneity has been implicated in treatment failure, the cellular and genetic factors ...
Jason Xu, Changya Chen, Jonathan H. Sussman, S. Yoshimura, T. Vincent, P. Pölönen, Jianzhong Hu, S. Bandyopadhyay, Omar Elghawy, Wenbao Yu, Joseph S. Tumulty, Chia-hui Chen, Elizabeth Y Li, C. Diorio, R. Shraim, H. Newman, Lahari Uppuluri, A. Li, Gregory M Chen, David W Wu, Yang-yang Ding, Jessica Xu, Damjan Karanfilovski, Tristan Lim, Miles Hsu, Anusha Thadi, Kyung Jin Ahn, Chi-Yun Wu, Jacqueline Peng, Yusha Sun, Alice Wang, Rushabh Mehta, David Frank, Lauren Meyer, M. Loh, E. Raetz, Zhiguo Chen, Brent L Wood, M. Devidas, K. Dunsmore, S. Winter, Ti-Cheng Chang, Gang Wu, S. Pounds, Nancy R. Zhang, William L. Carroll, S P Hunger, K. Bernt, Jun J. Yang, C. Mullighan, Kai Tan, D. Teachey   +51 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Summary of the XXVIIth Rencontres de Blois: Particle Physics and Cosmology

, 2015
This writeup summarises some of the highlights from the 2015 Rencontres de Blois, with a compression ratio of about 100:1 relative to the original presentations.Comment: 22 pages, 24 figures, presented at XXVIIth Rencontres de Blois, France, 31 May - 5
Salam, Gavin P.
core  

Bump-hunting in LHC ttbar events

, 2016
We demonstrate that a purposefully normalised NNLO top pair invariant mass differential spectrum can have very small theoretical uncertainty and, in particular, a small sensitivity to the top quark mass.
Czakon, Michal, Heymes, David, Mitov, Alexander   +2 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Las escuelas de educación artística un espacio para la convivencia, la creatividad y la seguridad

Entretextos
El objetivo del trabajo es conocer a través de las experiencias de los estudiantes y egresados cómo las escuelas de arte son un espacio de convivencia, creatividad y seguridad.
María Navarrete Radilla
doaj   +1 more source

La noción de cuerpo desde la clase de educación física. Manifestaciones sociales.

AiBi Revista de Investigación, Administración e Ingeniería, 2018
Valorar la noción del cuerpo desde la perspectiva de la clase de educación física, para la generación de una aproximación teórica centrada en el disfrute y la satisfacción del ser humano.
Yorley Beatriz Sánchez-Miranda, Arelys Florez-Villamizar   +1 more
doaj   +1 more source

$\psi(2S)$ and $\Upsilon(3S)$ hadroproduction in the parton Reggeization approach: Yield, polarization, and the role of fragmentation

, 2016
The hadroproduction of the radially excited heavy-quarkonium states $\psi(2S)$ and $\Upsilon(3S)$ at high energies is studied in the parton reggeization approach and the factorization formalism of nonrelativistic QCD at lowest order in the strong ...
Kniehl, B. A., Nefedov, M. A., Saleev, V. A.   +2 more
core   +1 more source