Results 131 to 140 of about 1,040,330 (310)

FDG‐PET Associations With Disease Severity and Outcomes in NMDA‐Receptor IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Patients with N‐methyl‐D‐aspartate (NMDA) receptor‐immunoglobulin G (IgG) autoimmune encephalitis (NMDAR‐IgG AE) demonstrate occipital lobe hypometabolism on baseline brain fluorodeoxyglucose‐positron emission tomography (bFDG‐PET).
Jonathan K. Lee, Jeffrey Lambe, Scott Johnson, Akua Abrah, Jennifer Bullen, Jeffrey A. Cohen, Tatchaporn Ongphichetmetha, Amy Kunchok   +7 more
wiley   +1 more source

Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth, Mert Sisman, Jinwei Zhang, Hyeong‐geol Shin, Xu Li, Bela Turk, Ali Fatemi, Thanh Nguyen, Eric Mallack   +8 more
wiley   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Measurement of $\Delta\Gamma_{s}$ and the CP-violating weak phase $\phi_s$ in the decay $B_s \ra J/\psi\phi$ by ATLAS

, 2012
A measurement of $B_s \ra J/\psi\phi$ decay parameters, including the CP-violating weak phase $\phi_s$ and the decay width difference $\Delta\Gamma_{s}$ is reported, using 4.9 $fb^{-1}$ of integrated luminosity collected in 2011 by the ATLAS detector ...
Smizanska, Maria
core  

ATLAS/ti: ein Werkzeug für die Textinterpretation

, 1994
Der Beitrag stellt das System ATLAS/ti für die computerunterstützte Textinterpretation vor. Ausgangspunkt für die Entwicklung der Software war die Erfahrung von Sozialwissenschaftlern, in der für qualitativ orientierte Untersuchungen typischen Datenfülle regelrecht zu ertrinken ("Zettels (Alb-) Traum").
openaire   +1 more source

Additional file 3: of Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

, 2018
Figure S6. Distribution of TIS scores within two MSI status categories and three cancer types. Points show individual samplesâ TIS scores. (PDF 31 kb)
Danaher, Patrick, Warren, Sarah, Lu, Rongze, Samayoa, Josue, Sullivan, Amy, Pekker, Irena, Wallden, Brett, Marincola, Francesco, Cesano, Alessandra   +8 more
openaire   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Additional file 7: of Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

, 2018
Figures. S8â S39. Checkpoints versus TIS score in all tumor types. (PDF 701 kb)
Danaher, Patrick, Warren, Sarah, Lu, Rongze, Samayoa, Josue, Sullivan, Amy, Pekker, Irena, Wallden, Brett, Marincola, Francesco, Cesano, Alessandra   +8 more
openaire   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Additional file 1: of Pan-cancer adaptive immune resistance as defined by the Tumor Inflammation Signature (TIS): results from The Cancer Genome Atlas (TCGA)

, 2018
Figure S7. Distribution of TIS scores in stage IV disease. TIS scores are shown for all TCGA patients with stage 4 disease. Cancer types are ordered by median TIS score in all patients, identical to Fig. 1. (PDF 30 kb)
Danaher, Patrick, Warren, Sarah, Lu, Rongze, Samayoa, Josue, Sullivan, Amy, Pekker, Irena, Wallden, Brett, Marincola, Francesco, Cesano, Alessandra   +8 more
openaire   +1 more source