Results 171 to 180 of about 957,277 (312)

A data-driven model of macrophage polarization states reveals an IFN macrophage signature in active Crohn's disease. [PDF]

Front Immunol
Lowe SC, Leitman M, Yan N, Hoffmann A.
europepmc   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

Advanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun, Yihang Yuan, Qian Qiu, Kexuan Tan, Xutong Li, Haotian Li, Luyang Kang, Yuting Gu, Ziheng Zhang, Jiayu He, Jiali Li, Junjie Lin, Zihan Xie, Kexing Han, Jiabin Li, Yang Zhang, Ting Wu, Yufeng Gao   +17 more
wiley   +1 more source

Fe-Modified TiO₂ Photocatalyst for Effective Indoor Bacterial Inactivation Using LED Light: Toward Safer Disinfection Technologies. [PDF]

ACS Omega
Angulo R, Mercado DF, Acelas N, Mejia MI, Velasco-Castaño JJ, Ávila-Torres YP, Pulgarin C, Jiménez JN, Torres-Palma RA, Porras J.   +9 more
europepmc   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

Generative artificial intelligence as an aid in interpreting thyroid FNA cytopathological images: Are we there yet? [PDF]

Cancer Cytopathol
Saieg M, Lago PP, Pusztaszeri MP.
europepmc   +1 more source

Multi‐Site Transfer Classification of Major Depressive Disorder: An fMRI Study in 3335 Subjects

Advanced Science, EarlyView.
The study proposes graph convolution network with sparse pooling to learn the hierarchical features of brain graph for MDD classification. Experiment is done on multi‐site fMRI samples (3335 subjects, the largest functional dataset of MDD to date) and transfer learning is applied, achieving an average accuracy of 70.14%.
Jianpo Su, Jian Qin, Hui Shen, Ling‐Li Zeng, Baojuan Li, Jin Liu, Xuemei Song, Li Liu, Weidan Pu, Tongjian Bai, Huaning Wang, Hong Yin, Kai Wang, Lingjiang Li, Dewen Hu   +14 more
wiley   +1 more source

Virtual brain twins for stimulation in epilepsy. [PDF]

Nat Comput Sci
Wang HE, Dollomaja B, Triebkorn P, Duma GM, Williamson A, Makhalova J, Lemarechal JD, Bartolomei F, Jirsa V.   +8 more
europepmc   +1 more source

RENEWING SOCIOLOGICAL ANALYSIS TOOLS IN THE AGE OF ARTIFICIAL INTELLIGENCE: A CRITICAL ASSESSMENT OF THE EXPERIENCES WITH MONKEYLEARN, NVIVO AI, AND ATLAS. TI

Metafizika Journal
This study aims to evaluate the effectiveness of artificial intelligence applications in renewing sociological analysis tools among postgraduate students, particularly those who are delayed in completing their scientific research. The study focuses on three primary applications: MonkeyLearn, NVivo AI, and Atlas.
openaire   +1 more source

Substantially Altered Local and Systemic Immunity in Ischemia‐Free Versus Conventional Liver Transplantation

Advanced Science, EarlyView.
This study investigates how ischemia‐free liver transplantation (IFLT) shapes both local and systemic immune responses compared with conventional liver transplantation (CLT). Our findings demonstrate that IFLT confers significant immunological protection by attenuating the STAT3‐HIF‐1α axis and enhancing the Heme‐HMOX1 pathway, two regulatory networks ...
Tao Luo, Shuai He, Shirui Chen, Dongmei Ye, Shibo Zhang, Di Liu, Dawei Zou, Linhe Wang, Huadi Chen, Jinghong Xu, Huanjie Liu, Ruiting Liu, Xi Tan, Yitong Wang, Jiayi Zeng, Runbing Mo, Yuexin Li, Yuyi Zhang, Tanyiyang Ruan, Tielong Wang, Zehua Jia, Yu Jia, Tongdi Fang, Yimou Lin, Xiaorui Liu, Yunhua Tang, Maogen Chen, Qiang Zhao, Anbin Hu, Weiqiang Ju, Yi Ma, Dongping Wang, Xiaofeng Zhu, Schlegel Andrea, Yuan Zhai, Kwan Man, Tullius G. Stefan, Yifang Gao, Jinxin Bei, Xiaoshun He, Zhiyong Guo   +40 more
wiley   +1 more source

Unveiling Novel Genetic Mutations and Prognostic Indicators in Breast Carcinoma: An Analysis of The Cancer Genome Atlas (TCGA) Data. [PDF]

Cureus
Butta R, Butta S.
europepmc   +1 more source