Results 191 to 200 of about 808,349 (313)
openaire +1 more source
First oxygen-oxygen collisions recorded by the ATLAS Experiment
Collision events recorded by the ATLAS experiment on 5 July 2025, when stable beams of oxygen, colliding at a centre-of-mass energy per nucleon pair of 5.36 TeV, were delivered to ATLAS by the ...
ATLAS Collaboration
core
Turkish teams meet at the national ATLAS workshop at Bogazici University 2014
Turkish teams meet at the national ATLAS workshop at Bogazici University, Turkey 2014 Image supporting ATLAS Blog - 26 May ...
ATLAS Collaboration
core
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan +29 more
wiley +1 more source
Differential neuronal survival defines a novel axis of sexual dimorphism in the Drosophila brain. [PDF]
Allen AM +4 more
europepmc +1 more source
Penfluridol Triggers GSDME‐Mediated Immunogenic Pyroptosis to Potentiate Antitumor Immunotherapy
A high‐throughput screen of FDA‐approved antipsychotics identifies penfluridol as a potent pyroptosis inducer acting via direct TTI1 inhibition. This triggers TNFA‐NFKB signaling and caspase‐8/‐3‐dependent GSDME cleavage. The compound stimulates antitumor immunity alone and synergizes with anti‐PD‐1 therapy, while low TTI1 expression emerges as a ...
Linfeng Li +11 more
wiley +1 more source
The Tumor-suppressive role of CNTNAP2 in glioma: Dual regulation of the NDN-ERK axis and M2 macrophage polarization. [PDF]
Wu Y +8 more
europepmc +1 more source
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao +11 more
wiley +1 more source
Targeted Genomic Region Masking Supports Accurate Variant Calling While Suppressing Low-Complexity Sequencing Artifacts. [PDF]
Kaligerou C +4 more
europepmc +1 more source
In non‐tumorous lung tissues, FOXN3 promotes the transcriptional activation of p53 by facilitating its recruitment to target promoters, thereby suppressing lung tumorigenesis through activation of the p53 signaling pathway. Conversely, in lung adenocarcinoma tissues, hyperphosphorylated FOXN3 dissociates from the promoters of p53‐responsive genes and ...
Jinjin Yu +16 more
wiley +1 more source

