Results 261 to 270 of about 808,349 (313)

A high-resolution atlas of the brain predicts lineage and birth order underlying neuronal identity. [PDF]

Cell Genom
Allen AM, Neville MC, Nojima T, Alejevski F, Agarwal D, Sims D, Goodwin SF.   +6 more
europepmc   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

Generative artificial intelligence as an aid in interpreting thyroid FNA cytopathological images: Are we there yet? [PDF]

Cancer Cytopathol
Saieg M, Lago PP, Pusztaszeri MP.
europepmc   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

Mechanical properties of white matter tracts in aging assessed via anisotropic MR elastography. [PDF]

Imaging Neurosci (Camb)
Caban-Rivera DA, Williams LT, McGarry MDJ, Smith DR, Van Houten EEW, Paulsen KD, Bayly PV, Johnson CL.   +7 more
europepmc   +1 more source

The role of discharge planning services in continuity of care for patients with diabetes: a scoping review. [PDF]

Front Public Health
Han X, An R, Zheng S, Zhou L, Luo Y, Lan X, Chen M.   +6 more
europepmc   +1 more source

Artificial Intelligence for Predicting Microsatellite Instability From Haematoxylin and Eosin-Stained Histopathology in Colorectal Cancer: An Updated Systematic Review and Meta-Analysis. [PDF]

Cureus
Kanani DA, Salot PH, Nagda J.
europepmc   +1 more source

A Data-Driven Normalization Framework for Subject-Specific Cerebrovascular Reactivity Assessment in Cerebrovascular Disease. [PDF]

J Magn Reson Imaging
Zhu Y, Dogra S, Wang X, Polimeni JR, Dehkharghani S.   +4 more
europepmc   +1 more source

Unveiling Novel Genetic Mutations and Prognostic Indicators in Breast Carcinoma: An Analysis of The Cancer Genome Atlas (TCGA) Data. [PDF]

Cureus
Butta R, Butta S.
europepmc   +1 more source