Results 71 to 80 of about 957,277 (312)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

UNA APROXIMACIÓN A LOS PATRONES DE COMUNICACIÓN ENTRE EL PROFESOR MENTOR Y EL PROFESOR-ESTUDIANTE EN EL CONTEXTO DE LA PRÁCTICA PEDAGÓGICA

open access: yesEducación XX1, 2012
Puesto que la Formación Inicial Docente (FID) ha sido, en este último tiempo, parte de la agenda nacional del Ministerio de Educación de Chile, este estudio tiene como objetivo comprender los patrones de comunicación establecidos entre un grupo ...
Claudio Díaz Larenas   +1 more
doaj   +1 more source

The midpoint between dipole and parton showers

open access: yes, 2015
We present a new parton-shower algorithm. Borrowing from the basic ideas of dipole cascades, the evolution variable is judiciously chosen as the transverse momentum in the soft limit. This leads to a very simple analytic structure of the evolution.
Höche, Stefan, Prestel, Stefan
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Visual representations of literacy in the press : report to the Leverhulme Trust February 2001. [PDF]

open access: yes, 2001
This project investigated the ways in which literacy practices are represented in visual images in a range of British newspapers. The aims of the research were: a) to contribute to theoretical understandings of literacy as socio-cultural practice and ...
Hamilton, Mary, Shaw, Ian
core  

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Expectativas que poseen docentes universitarios de carreras de pedagogía en relación al uso de las TIC

open access: yesPixel-Bit, 2015
El trabajo que se presenta a continuación se trata de un estudio cualitativo aplicado en la Facultad de  Educación de la Universidad Católica del Maule, en Chile, en relación a las expectativas de los académicos en torno a la integración de las ...
Marcelo Humberto Rioseco Pais   +1 more
doaj   +1 more source

Ti/4H-SiC Schottky diode breakdown voltage with different thickness of 4H-SiC epitaxial layer

open access: yesJournal of Physics: Conference Series, 2018
Breakdown voltage for Ti/4H-SiC type Schottky diode with six guard rings have been calculated theoretically and by mean of numerical simulations. It is shown that the breakdown voltage can be increase at the minimum on 100 V in case when thickness of the
S. Sedykh   +5 more
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

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